[Hub]/) : Traits : Impedance of arm (right) :

chr20:20,407,782-21,919,054

Best TWAS P=2.23e-11 · Best GWAS P=3.17e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PLK1S1 0.08 0.01 lasso 3 0.04 1.1e-05 -5.5 -5.6 2.8e-08 0.80 0.03 0.97 FALSE
2 GTEx Artery Tibial PLK1S1 0.07 0.08 enet 10 0.08 4.0e-07 -6.5 -6.7 2.2e-11 0.97 0.03 0.97 TRUE
3 GTEx Esophagus Mucosa PLK1S1 0.11 0.11 lasso 5 0.09 7.8e-07 -5.8 -5.7 1.1e-08 0.88 0.07 0.93 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic PLK1S1 0.21 0.09 lasso 6 0.12 5.3e-07 -6.5 -5.8 5.5e-09 0.96 0.07 0.93 FALSE
5 GTEx Skin Sun Exposed Lower leg PLK1S1 0.15 0.13 enet 10 0.15 3.9e-12 -6.0 -5.6 2.8e-08 0.87 0.67 0.33 FALSE
6 GTEx Testis PLK1S1 0.64 0.34 enet 33 0.39 1.0e-18 -6.0 -6.3 3.0e-10 0.81 0.69 0.31 FALSE
7 GTEx Whole Blood PLK1S1 0.08 0.04 enet 9 0.02 4.0e-03 -6.0 -6.5 8.3e-11 0.92 0.05 0.95 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma PLK1S1 0.05 0.07 enet 9 0.07 5.5e-15 -5.7 -6.0 2.7e-09 0.93 0.12 0.88 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma PLK1S1 0.04 0.03 blup 64 0.04 4.0e-05 -6.0 -6.5 7.8e-11 0.93 0.07 0.92 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma PLK1S1 0.09 0.02 blup 64 0.05 3.1e-03 -5.5 -6.6 4.2e-11 0.80 0.02 0.61 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma PLK1S1 0.19 0.12 enet 14 0.13 4.3e-13 -5.9 -5.8 5.0e-09 0.82 0.65 0.35 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma PLK1S1 0.06 0.04 lasso 3 0.04 1.5e-04 -5.9 -6.0 2.4e-09 0.90 0.11 0.70 FALSE