Best TWAS P=2.21e-09 · Best GWAS P=1.23e-09 conditioned to 0.000356
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LIME1 | 0.04 | 0.00 | bslmm | 439 | 0.01 | 3.3e-02 | 3.5 | -5.9 | 2.9e-09 | 0.43 | 0.03 | 0.90 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | SLC2A4RG | 0.12 | 0.01 | enet | 15 | 0.03 | 7.2e-04 | -4.2 | -5.2 | 2.1e-07 | 0.31 | 0.09 | 0.35 | FALSE |
| 3 | YFS | Blood | SLC2A4RG | 0.03 | 0.02 | lasso | 11 | 0.02 | 4.2e-08 | -5.8 | -5.3 | 1.2e-07 | 0.49 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LIME1 | 0.04 | 0.03 | lasso | 3 | 0.02 | 7.2e-04 | -5.8 | -6.0 | 2.2e-09 | 0.50 | 0.00 | 0.96 | TRUE |