TWAS
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Genes
Traits
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Traits
:
Impedance of arm (right)
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chr1:220,359,347-221,753,645
Best TWAS P=5.89e-14 · Best GWAS P=5.73e-16 conditioned to 1.14e-05
220.4M
220.6M
220.8M
221M
221.2M
221.4M
221.6M
221.8M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
HLX
0.06
0
enet
9
0
0.53
-3.7
-7.5
5.9e-14
-0.62
0.03
0.6
TRUE