Best TWAS P=6.91e-10 · Best GWAS P=3.22e-06 conditioned to 0.839
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | FBLN7 | 0.50 | 0.19 | lasso | 8 | 0.31 | 1.5e-24 | 4.7 | -6.2 | 6.9e-10 | -0.78 | 0.00 | 0.98 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FBLN7 | 0.09 | 0.04 | blup | 62 | 0.05 | 4.1e-06 | -3.5 | -6.2 | 7.2e-10 | -0.54 | 0.04 | 0.19 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | FBLN7 | 0.04 | 0.00 | blup | 61 | 0.01 | 2.4e-02 | -3.5 | -5.9 | 4.7e-09 | -0.49 | 0.00 | 0.11 | FALSE |