TWAS
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Models
Genes
Traits
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Traits
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Impedance of arm (right)
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chr2:112,213,244-113,641,631
Best TWAS P=6.91e-10 · Best GWAS P=3.22e-06 conditioned to 0.839
112.2M
112.4M
112.6M
112.8M
113M
113.2M
113.4M
113.6M
0
1
2
3
4
5
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Thyroid
FBLN7
0.50
0.19
lasso
8
0.31
1.5e-24
4.7
-6.2
6.9e-10
-0.78
0.00
0.98
TRUE
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
FBLN7
0.09
0.04
blup
62
0.05
4.1e-06
-3.5
-6.2
7.2e-10
-0.54
0.04
0.19
FALSE
3
The Cancer Genome Atlas
Thyroid Carcinoma
FBLN7
0.04
0.00
blup
61
0.01
2.4e-02
-3.5
-5.9
4.7e-09
-0.49
0.00
0.11
FALSE