Hub : Genes

FBLN7

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2090 0.0410 0.0e+00 0.092 0.149 0.201 0.177 0.205 2.5e-11 9.1e-18 5.3e-24 4.5e-21 2.2e-24
2 GTEx Adipose Subcutaneous 0.1240 0.0500 5.1e-03 0.032 NA 0.037 NA 0.014 1.2e-03 NA 5.3e-04 NA 2.2e-02
3 GTEx Artery Aorta 0.2840 0.0670 2.4e-06 0.151 NA 0.115 NA 0.052 1.1e-08 NA 7.2e-07 NA 7.3e-04
4 GTEx Artery Tibial 0.4828 0.0573 0.0e+00 0.367 NA 0.379 NA 0.370 5.0e-30 NA 3.3e-31 NA 2.3e-30
5 GTEx Brain Cerebellum 0.1440 0.0680 5.8e-03 0.137 NA 0.125 NA 0.000 7.4e-05 NA 1.6e-04 NA 3.3e-01
6 GTEx Brain Cortex 0.2470 0.1050 4.8e-03 0.002 NA 0.001 NA 0.003 2.7e-01 NA 3.0e-01 NA 2.6e-01
7 GTEx Cells Transformed fibroblasts 0.2200 0.0570 2.3e-06 0.129 NA 0.131 NA 0.132 7.2e-10 NA 5.2e-10 NA 4.5e-10
8 GTEx Esophagus Muscularis 0.1360 0.0510 4.5e-04 0.092 NA 0.072 NA 0.074 3.3e-06 NA 3.9e-05 NA 3.0e-05
9 GTEx Lung 0.1507 0.0527 2.3e-04 0.008 NA 0.056 NA 0.018 7.2e-02 NA 4.4e-05 NA 1.5e-02
10 GTEx Pancreas 0.1350 0.0660 3.4e-03 0.027 NA 0.025 NA 0.022 2.5e-02 NA 3.2e-02 NA 3.9e-02
11 GTEx Skin Sun Exposed Lower leg 0.1090 0.0480 2.0e-03 0.039 NA 0.043 NA 0.069 3.1e-04 NA 1.6e-04 NA 2.4e-06
12 GTEx Thyroid 0.4980 0.0570 0.0e+00 0.187 NA 0.294 NA 0.314 2.7e-14 NA 8.4e-23 NA 1.5e-24
13 GTEx Vagina 0.3930 0.1020 5.1e-04 0.051 NA 0.017 NA 0.070 2.6e-02 NA 1.3e-01 NA 1.1e-02
14 METSIM Adipose 0.1372 0.0356 2.4e-10 0.030 0.071 0.081 0.076 0.070 2.0e-05 9.5e-11 4.1e-12 1.8e-11 1.3e-10
15 ROSMAP Brain Pre-frontal Cortex 0.3152 0.0511 0.0e+00 0.091 0.235 0.255 0.205 0.248 1.0e-11 9.4e-30 1.3e-32 8.1e-26 1.4e-31
16 YFS Blood 0.0332 0.0131 4.0e-06 0.003 0.017 0.016 0.017 0.011 3.1e-02 1.9e-06 4.1e-06 1.9e-06 1.3e-04
17 TCGA Colon Adenocarcinoma 0.1900 0.0780 9.5e-04 0.006 0.022 0.010 NA 0.005 1.4e-01 2.0e-02 7.7e-02 NA 1.5e-01
18 TCGA Lung Squamous Cell Carcinoma 0.0490 0.0294 7.9e-03 0.007 0.014 0.020 NA 0.017 4.5e-02 9.1e-03 2.4e-03 NA 4.2e-03
19 TCGA Ovarian Serous Cystadenocarcinoma 0.0390 0.0220 7.3e-03 0.010 0.003 -0.004 NA 0.001 6.1e-02 1.9e-01 7.7e-01 NA 2.9e-01
20 TCGA Prostate Adenocarcinoma 0.0922 0.0342 1.4e-05 0.044 0.051 0.038 NA 0.037 2.1e-05 4.1e-06 7.7e-05 NA 9.3e-05
21 TCGA Thyroid Carcinoma 0.0380 0.0230 9.8e-03 0.003 0.012 0.002 NA 0.005 1.5e-01 2.4e-02 1.9e-01 NA 9.4e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bipolar Disorder (2018) 0.7 1.2 4.2 -0.9 0.8 1.1 1.4 -1.0 -1.5 -1.2 -1.1 -0.5 -0.0 -0.7 0.9 -0.5 1.1 -0.8 -0.1 2.0 0.2 1.4 1.7 1.1
Bipolar Disorder or Schizophrenia 0.4 0.9 3.4 -0.0 0.7 0.6 1.1 -0.1 -1.7 -0.4 -1.2 -0.9 -1.8 -0.2 -0.2 -1.0 0.6 0.6 -0.5 1.8 1.2 0.4 0.8 -0.0
Depressed Affect (Nagel 2018) 0.7 1.4 5.3 1.9 -0.2 0.2 -0.2 0.5 1.4 0.1 0.0 -0.0 -1.9 0.2 -1.5 -1.3 -1.0 2.3 -0.2 0.4 2.3 -1.1 -1.1 -1.4
Depression (Nagel 2018) 1.4 2.1 5.4 2.3 -1.4 -0.5 -1.0 0.7 1.4 -1.1 -0.6 -1.1 -1.9 -0.6 -1.8 -1.5 -1.3 2.2 -0.3 0.8 2.1 -1.0 -2.0 -1.6
Intelligence (Savage-Jansen 2018) 0.1 0.4 1.6 -0.7 0.1 -0.3 0.6 -0.9 0.1 -0.3 0.3 0.4 0.1 0.0 0.3 0.6 0.7 -1.0 1.3 -0.1 -0.5 0.5 1.2 0.5
Neuroticism (Nagel 2018) 0.8 1.9 12.1 1.8 -0.3 0.1 -0.4 0.8 1.2 -0.8 -0.9 -0.9 -3.5 0.5 -1.5 -0.8 -0.7 2.3 -0.4 0.1 1.9 -1.2 -1.7 -1.5
Schizophrenia (2018) 0.4 0.8 5.4 0.7 0.3 -0.0 0.2 0.7 -0.9 0.5 -0.7 -0.7 -2.3 0.3 -1.0 -0.9 -0.1 1.4 -0.5 0.8 1.4 -0.7 -0.3 -0.9
Schizophrenia vs Biploar Disorder 1.7 2.3 6.7 2.2 -0.9 -1.6 -2.1 1.6 1.3 1.0 0.7 0.2 -0.6 0.4 -2.6 -1.0 -1.8 1.9 0.7 -0.9 1.6 -1.7 -2.0 -1.8
Worry (Nagel 2018) 0.4 0.7 7.0 -0.0 -0.4 0.8 0.2 0.4 -0.5 -1.5 -1.4 -0.5 -2.6 0.8 0.2 0.7 0.1 0.3 -0.4 0.2 -0.4 -0.1 -1.1 -0.2
Alzheimer’s Disease (in mother) 0.3 0.3 1.3 -0.9 0.6 0.1 0.6 0.0 -0.5 0.2 0.0 0.6 0.4 1.1 1.2 0.6 -0.2 -0.0 -0.3 0.6 0.3 0.2 0.7 0.7
Alzheimer’s Disease (in father) 0.3 0.3 1.1 0.1 0.0 0.8 0.1 -0.6 -0.9 -0.9 -0.3 -0.4 1.1 -0.7 -0.1 -0.1 0.2 -0.4 -0.8 -0.6 -0.7 0.2 -0.6 -0.3
Alzheimer’s Disease (including proxy) 0.2 0.3 1.4 -0.6 -0.1 -0.2 -0.6 0.3 -0.7 0.4 0.7 0.7 0.9 0.4 0.7 0.5 -1.2 0.1 0.3 0.2 0.2 -0.4 -0.0 0.1
Crohns Disease (2017) 1.3 2.9 12.0 -1.2 -1.3 0.0 1.2 -1.8 -1.3 -3.5 -3.4 -2.9 -0.3 -1.8 0.4 -1.9 0.4 -1.7 -1.4 -0.0 -1.8 1.4 -0.9 0.4
Irritable Bowel Disease (IBD) 1.0 2.3 9.7 -0.4 -1.2 -0.3 0.8 -1.7 -0.7 -2.9 -3.1 -3.1 -0.5 -2.3 -0.7 -2.2 -0.4 -0.6 -1.1 -0.5 -0.8 1.2 -0.9 -0.1
Ulcerative Colitis (UC) 0.6 1.1 4.6 0.4 -1.0 -0.5 0.1 -0.8 -0.0 -1.4 -1.8 -2.1 -0.4 -1.9 -1.2 -1.9 -0.8 0.3 -0.2 -0.1 0.4 0.7 -0.5 -0.3
Major Depression (MDD) 0.3 0.4 3.1 0.3 -0.9 0.4 -0.1 0.0 0.1 -0.9 -0.1 -0.9 -1.8 -0.5 -0.5 -0.9 0.0 0.2 -0.7 0.2 0.6 0.0 -0.2 -0.4
Reaction Time 2.0 3.9 13.6 -2.7 -1.4 -1.0 0.3 0.3 -2.4 -0.9 0.4 2.1 1.7 0.8 2.9 2.4 0.8 -3.7 2.7 1.2 -3.1 1.3 1.4 2.3
Verbal and Numeric Reasoning (VNR) 0.2 0.5 2.3 0.2 -1.0 -1.0 -0.1 -0.7 1.1 -1.0 -0.4 -0.4 0.2 -1.5 -0.5 -0.7 -0.3 -0.7 -0.1 -0.5 0.1 0.7 -0.1 -0.2
Breast Cancer 0.3 0.7 3.3 1.2 0.5 -0.2 -0.0 0.2 1.8 0.7 0.6 -0.1 1.8 -0.6 -1.1 -0.5 -0.3 1.3 -0.7 -0.7 1.0 -0.6 -0.2 -0.5
Ovarian Cancer 0.9 1.2 4.1 0.8 0.4 -0.2 -0.7 1.3 0.8 0.8 1.1 -0.0 -1.6 0.9 -0.7 0.8 -0.1 1.1 -0.6 -2.0 0.9 -2.0 -1.4 -1.8
Prostate Cancer 0.3 0.5 2.3 -0.0 1.0 -0.0 1.2 -0.7 -0.0 -0.3 -0.4 0.4 -0.3 -0.2 -0.4 -0.3 0.3 -0.5 1.5 0.8 0.3 0.7 0.9 1.0
Age at First Birth 2.3 3.4 10.5 -1.4 2.2 1.1 2.1 -1.4 -1.1 1.2 0.8 2.5 3.2 1.3 1.9 1.4 2.6 -1.3 1.3 1.1 -0.3 2.1 3.1 2.1
Bipolar Disorder (2011) 0.4 0.4 1.6 -0.4 0.2 0.6 0.9 -0.3 -0.7 0.2 0.1 0.2 -0.5 -0.3 0.9 0.4 0.9 0.1 -0.3 1.3 0.5 0.7 0.9 0.3
Body Mass Index (BMI) (2010) 0.3 0.4 2.8 -0.1 -0.1 0.0 -0.0 -0.3 0.8 -0.5 -0.3 -1.0 -0.1 -1.7 -0.6 -0.7 -0.6 0.0 -0.8 -0.6 -0.1 0.1 0.4 -0.2
Coronary Artery Disease (CAD) 0.8 0.9 6.0 0.4 -2.4 -0.5 -0.7 0.5 0.2 -1.2 -1.2 -1.4 -1.0 -1.4 0.0 -0.6 -1.2 -0.2 0.3 0.3 -0.4 -0.3 -1.4 -0.6
Crohns Disease (2012) 0.7 1.1 4.9 -0.0 -1.1 -0.4 0.2 -0.6 -0.4 -2.0 -1.9 -2.2 0.2 -0.4 -0.5 -1.6 0.3 -0.3 -1.1 -1.0 -1.1 0.3 -1.1 -0.5
Mean Putamen Volume 0.4 0.4 5.2 -0.1 0.6 -0.1 -0.0 0.9 0.1 -0.1 -0.2 0.3 -2.3 -0.6 -0.1 0.8 0.1 -0.5 -0.2 -0.1 -0.5 -0.9 -0.2 -0.4
Fasting Glucose 1.5 1.8 5.0 -1.1 1.1 2.0 1.9 -2.2 -0.2 -0.7 -0.6 -0.8 1.3 0.3 1.5 0.1 0.7 -0.9 -1.2 2.1 -0.0 2.1 1.3 1.7
HbA1C 0.6 0.7 6.0 0.8 -0.2 -1.3 -0.9 1.2 0.4 0.5 0.4 0.7 -0.2 1.0 -0.1 0.5 -0.2 0.6 2.4 0.6 0.3 -0.7 0.4 -0.2
HDL Cholesterol 0.2 0.3 1.7 0.4 -0.9 0.3 -0.6 0.6 0.5 0.7 0.3 -0.2 0.2 -0.3 -0.4 0.0 -0.5 -0.2 -1.3 -0.4 0.0 -0.2 -0.2 -0.6
LDL Cholesterol 0.9 1.5 4.8 -0.6 0.9 1.5 1.2 -1.1 -1.6 -0.1 -0.0 1.6 2.2 0.1 1.4 0.5 1.0 -0.6 -0.6 1.4 0.5 2.0 2.0 1.1
Lupus 0.8 1.3 6.1 0.6 -1.4 -1.7 -1.6 2.5 -0.1 -0.3 0.1 -0.2 -1.7 -0.1 -0.7 -0.3 -1.0 0.4 0.7 -0.8 -0.0 -1.6 -1.2 -1.7
Neuroticism (2016) 0.8 1.1 4.0 1.1 -1.3 -1.0 -1.5 1.3 1.0 -0.8 -0.5 -0.9 -1.3 0.5 -0.9 -0.8 -1.0 0.3 -0.4 0.9 0.1 -1.6 -2.0 -0.6
Primary Biliary Cirrhosis 1.2 1.7 4.2 0.5 -1.5 -1.3 -1.3 0.6 -0.9 -1.6 -1.7 -1.6 -1.6 -1.7 -1.4 -2.0 -1.9 -0.1 -1.5 -0.5 0.2 0.3 -1.3 -1.4
Rheumatoid Arthritis 0.7 1.0 3.1 0.2 -1.5 -0.9 -0.9 0.5 0.3 0.2 -0.3 -1.8 -1.8 -0.3 -1.3 -1.0 -1.1 -0.3 0.8 -1.5 -0.9 -0.7 -1.1 -0.7
Schizophrenia (2014) 1.1 2.4 7.1 2.1 -0.7 -0.9 -0.9 1.4 -0.1 0.2 -0.7 -1.4 -2.7 -0.7 -2.5 -2.1 -1.4 2.1 0.4 0.9 2.5 -1.4 -1.4 -1.8
Triglycerides 0.2 0.3 1.4 0.1 0.5 0.0 0.1 0.1 -0.7 -0.0 -0.7 -0.5 -0.8 1.2 -0.6 -1.0 -0.1 0.8 -0.0 -0.1 0.1 0.0 -0.1 0.0
Type 2 Diabetes (T2D) (2012) 0.3 0.4 1.3 -0.2 -0.5 -0.6 -0.3 0.2 -1.0 -1.2 -0.8 -0.5 -1.1 -0.0 -0.3 0.1 0.2 0.1 -0.2 -0.8 -0.7 -0.0 -0.9 -0.3
Ulcerative Colitis 0.7 1.0 3.1 0.5 -1.4 -1.1 -0.6 0.2 -0.2 -1.5 -1.7 -1.8 -0.4 -1.6 -1.2 -1.2 -1.1 0.2 0.3 -0.1 0.6 0.0 -1.1 -1.0
Blood Eosinophil Count 0.1 0.7 2.2 -0.3 1.3 1.4 1.5 -1.1 -0.1 -1.1 0.1 0.5 0.0 0.5 0.5 0.2 1.4 -0.8 0.6 0.7 -0.3 0.9 0.2 0.9
Blood Platelet Count 0.5 5.6 13.1 3.0 -2.5 -2.8 -2.3 2.4 3.6 1.8 2.5 -0.0 -0.6 -2.3 -3.0 -2.2 -2.6 3.0 1.7 -1.8 1.9 -2.4 -1.7 -2.7
Blood Red Count 0.9 8.8 29.0 -2.4 0.0 2.3 3.2 -4.8 -2.3 -2.9 -5.3 -3.9 0.6 -1.0 1.0 -1.8 1.7 -2.9 -5.4 1.3 -1.3 5.0 1.3 2.9
Blood White Count 4.2 31.3 91.2 -5.4 3.9 7.2 7.7 -8.5 -3.6 -6.8 -6.2 -2.6 2.9 -0.7 5.5 0.5 6.0 -5.3 -4.7 5.2 -2.2 9.6 5.1 7.1
Heel T-Score 2.8 22.2 39.8 6.3 -4.2 -5.1 -5.9 4.6 6.1 3.6 4.0 -1.1 -1.8 -4.3 -5.8 -5.9 -6.2 5.9 4.0 -0.3 4.9 -5.0 -2.5 -4.9
BMI 0.5 2.8 13.3 0.6 -1.1 1.5 0.7 -1.5 0.5 -1.9 -1.7 -2.9 -2.5 -2.9 -0.8 -2.7 -0.2 -0.1 -3.6 0.3 -0.1 0.3 -1.5 -0.3
Height 0.2 3.7 16.4 1.2 -0.2 -1.2 -2.3 2.9 0.6 0.4 3.0 1.5 0.1 1.6 -0.8 2.6 0.5 0.9 0.9 -2.3 -0.4 -4.0 -2.8 -2.7
Waist Hip Ratio (WHR) 0.4 2.0 10.2 -0.7 0.7 0.8 0.4 -1.1 -1.6 -3.2 -2.0 -1.3 -1.5 -1.9 0.4 -0.9 2.0 -1.3 -0.1 2.6 0.3 1.0 0.5 0.6
Systolic Blood Pressure 2.2 11.1 24.1 -3.6 2.7 4.8 4.8 -4.9 -2.8 -3.9 -4.8 -2.9 -0.7 0.3 3.0 1.2 3.2 -2.8 -3.7 1.8 -1.8 4.5 2.1 3.5
Smoking Status 0.4 0.9 3.3 0.5 0.3 0.9 -0.2 0.0 -1.8 -0.7 -1.0 -0.7 -1.3 -0.6 -1.0 -1.0 -0.1 0.2 -1.8 -0.6 0.5 -0.5 -1.5 -1.1
Allergy or Eczema 0.3 0.9 2.8 0.6 0.6 -0.4 0.4 1.0 -1.0 1.7 -0.1 1.4 -1.4 1.0 0.1 0.8 -1.2 1.0 1.3 -0.5 1.6 -0.2 0.5 -0.6
Cardiovascular Disease 2.2 7.3 25.9 -1.9 2.7 5.1 3.9 -4.0 -2.1 -3.0 -3.7 -2.8 -1.6 -0.6 1.5 -0.4 2.9 -1.3 -4.1 2.0 0.1 3.0 1.3 1.9
Hypothyroidism (self reported) 1.0 2.2 12.3 -0.2 0.4 1.8 1.6 -1.9 -0.0 -2.5 -2.2 -1.6 -1.1 -1.3 -0.2 -1.0 0.8 0.1 -3.5 0.7 0.6 2.3 -0.1 0.2
Respiratory disease 0.4 0.9 2.9 -0.8 0.9 0.4 1.5 -0.1 -0.7 0.7 0.2 0.9 -0.6 1.2 1.7 1.6 1.0 -0.6 1.2 0.5 -0.4 0.5 1.1 1.1
Type 2 Diabetes (T2D) (2018) 2.4 4.6 11.8 -2.5 1.9 2.4 2.6 -3.4 -2.1 -2.4 -2.5 -2.6 0.3 -0.6 1.6 -0.7 2.2 -2.0 -2.3 1.9 -1.6 2.7 1.7 2.0
Lung FEV1/FVC ratio 1.2 6.3 20.3 3.0 -3.5 -2.8 -3.5 1.7 4.5 0.1 2.0 -1.7 2.4 -2.6 -2.6 -2.4 -2.1 2.2 1.5 -2.5 0.3 -2.1 -2.5 -2.8
Lung FVC 1.1 5.7 16.8 2.0 -3.2 -3.4 -4.1 3.5 1.2 0.7 1.3 -0.3 -0.0 0.2 -2.3 -0.3 -3.4 1.8 3.2 -1.2 0.1 -2.8 -3.5 -2.7
Neuroticism 0.3 0.8 5.2 1.1 -0.4 -0.1 -0.3 0.6 0.8 -0.9 -1.1 -0.9 -2.3 0.6 -1.0 -0.7 -0.5 1.2 -0.0 0.6 0.9 -0.6 -1.2 -0.6
Chronotype (morning person) 1.6 3.7 14.6 -1.4 0.5 0.4 2.0 -2.9 -0.9 -3.7 -3.8 -1.8 1.1 -1.0 0.6 -1.0 0.9 -2.3 -2.7 -0.0 -0.4 3.4 0.1 1.2
Hair Pigment 0.0 1.4 4.6 -1.2 1.2 1.0 1.1 -0.2 -2.1 0.8 -0.1 1.3 -1.1 0.7 1.3 0.5 1.0 -1.3 0.4 2.1 0.4 0.5 1.9 1.4
Tanning 0.0 0.4 1.7 0.9 0.7 1.0 -0.6 0.3 -0.2 0.6 0.8 0.8 0.4 0.8 -0.6 0.1 0.2 1.3 -0.5 -0.4 0.5 -0.4 -0.6 -0.6
Hand grip strength (left) 1.6 4.3 9.7 -3.0 2.4 1.2 2.4 -1.7 -3.0 -0.6 -0.5 0.9 -0.1 2.4 2.5 1.7 2.2 -2.6 1.2 2.3 -1.3 2.0 2.4 3.1
Number of treatments/medications taken 0.7 1.2 7.6 -0.2 0.7 2.8 1.6 -0.9 -1.5 -1.3 -1.0 -0.7 -1.6 -0.1 0.5 0.1 1.6 0.2 -1.6 -0.1 0.0 0.2 0.5 0.1
Average weekly spirits intake 0.6 0.8 4.4 1.4 -0.6 0.2 -0.8 0.5 0.9 0.7 0.2 0.1 0.9 0.1 -0.8 -0.6 -0.9 1.7 -0.4 0.5 2.1 -0.5 -0.7 -0.8
Sensitivity / hurt feelings 2.0 3.4 7.1 2.6 -1.7 -2.5 -2.0 2.2 2.1 -0.7 -1.0 -1.0 -2.2 -1.0 -2.1 -1.4 -2.0 2.1 0.7 -0.6 1.7 -1.6 -2.7 -2.2
Frequency of depressed mood in last 2 weeks 1.4 2.0 7.6 2.4 -0.9 -0.6 -0.7 0.8 1.6 -0.1 -0.3 -0.3 -1.7 -0.3 -1.8 -1.6 -1.1 2.8 -0.4 0.9 2.8 -1.0 -1.5 -1.6
Hearing difficulty/problems: Yes 0.9 1.3 4.2 1.1 1.8 1.3 1.3 -1.1 1.2 0.6 -1.4 -0.4 -0.7 -0.1 -1.5 -0.4 0.2 1.9 -2.0 -0.8 1.7 0.3 -0.3 -0.3
Relative age of first facial hair 0.6 1.2 5.5 -0.1 -0.1 -1.0 -0.5 1.2 0.3 2.3 1.7 1.5 1.3 1.1 0.6 1.8 -0.0 0.6 0.1 -1.8 -0.2 -0.3 0.8 -0.7
Other serious medical condition/disability diagnosed by doctor 1.4 1.8 5.6 0.6 1.3 1.8 1.5 -1.3 -0.6 -2.1 -2.0 -1.0 -2.4 -0.2 -0.9 -1.1 1.6 0.9 -1.6 0.8 1.7 1.0 -0.4 0.2
Ever used hormone-replacement therapy (HRT) 0.5 0.6 2.7 0.4 -1.6 -1.1 -1.0 1.2 0.2 0.6 0.1 -0.6 0.3 -0.9 -0.3 -0.3 -1.0 0.8 -0.2 -0.4 -0.1 -0.8 -0.7 -0.9
Ever had hysterectomy (womb removed) 0.9 1.0 3.8 0.4 0.0 0.6 0.4 -0.3 0.7 -1.7 -1.3 -1.5 -1.6 -0.6 -0.6 -0.9 1.2 0.9 0.5 2.0 1.4 0.7 -0.1 0.4
Systolic blood pressure, automated reading 2.0 5.7 11.7 -3.1 1.3 3.2 3.0 -3.4 -1.9 -3.1 -3.4 -2.5 -1.2 -0.7 2.3 1.3 1.9 -2.7 -2.6 1.0 -2.5 2.8 1.0 2.3
Eye problems/disorders: Diabetes related eye disease 1.4 1.6 9.2 -1.6 -0.2 -0.0 0.5 -0.9 -1.4 -0.9 -1.0 -1.6 -0.5 0.4 1.0 -0.9 0.6 -1.5 1.1 3.0 -0.8 1.4 1.5 1.9
Angina 0.8 1.1 5.4 -0.6 0.6 1.3 0.6 0.1 -0.7 -0.7 0.3 1.6 2.3 1.1 1.8 2.0 1.1 -0.3 -0.2 0.3 -0.2 0.5 0.1 0.4
Medication for hormone replacement therapy 0.3 0.4 2.4 -0.0 -0.6 -0.5 -0.1 0.2 -0.2 -0.6 -1.3 -0.7 -1.1 -0.3 -0.3 -0.2 -0.1 0.1 -1.5 -0.4 -0.1 -0.1 -0.9 -0.4
Vitamin and mineral supplements 0.6 0.9 4.2 0.9 0.4 1.0 0.3 -0.6 0.3 -0.2 -0.5 -0.5 -0.1 -1.1 -1.2 -1.3 0.3 1.5 -2.0 0.2 1.7 0.4 -0.2 -0.8
Supplements: Zinc 0.5 0.5 2.3 0.2 0.3 -0.5 0.2 -0.4 0.4 -0.8 -1.5 -0.8 -1.5 -0.7 -1.0 -0.9 0.2 -0.5 -0.5 0.5 0.5 0.4 -0.5 0.4
Medication: Co-codamol 0.7 0.8 6.6 -0.1 0.2 0.8 -0.5 1.3 -1.2 0.5 1.1 0.2 -2.6 1.3 0.1 0.6 0.4 0.3 0.6 -0.2 -0.5 -1.6 -0.2 -0.5
Medication: Metformin 1.7 2.4 6.8 -1.3 0.9 1.1 2.1 -2.6 -0.5 -1.5 -1.8 -2.0 1.1 0.4 0.7 -1.5 1.6 -1.1 -0.7 2.0 -0.6 2.2 1.5 2.2
Diabetes (father) 1.3 1.7 4.8 1.0 0.2 0.0 -0.3 -0.2 1.0 -1.7 -1.8 -2.1 -0.7 0.8 -1.7 -1.2 -0.1 1.4 -1.7 -1.8 1.0 -0.5 -2.2 -1.5
Diabetes (mother) 0.5 0.6 2.0 -0.2 0.6 0.5 0.9 -0.5 0.6 -0.5 -0.8 -1.3 -0.7 0.5 -0.1 -1.3 1.4 -0.3 0.1 1.1 0.6 0.5 0.7 0.9
Severe depression (siblings) 2.4 2.7 6.0 2.2 -0.6 -1.0 -1.6 0.3 2.0 -0.2 -0.3 -1.2 -1.4 -1.7 -2.1 -2.0 -2.2 2.5 -1.5 -0.7 2.1 -1.0 -2.3 -2.1
Pack years adult smoking proportion 2.5 3.9 18.7 -2.5 2.3 2.1 1.9 -1.3 -4.3 -0.8 -1.2 1.4 -0.4 2.0 2.9 1.6 1.6 -2.3 -1.1 2.4 -0.8 1.2 1.2 2.0
Impedance of leg (right) 0.8 3.7 16.3 0.1 0.9 1.0 1.4 -2.0 -0.6 -4.0 -4.0 -3.1 -1.3 0.5 -2.5 -1.9 1.9 0.2 -1.6 0.1 1.5 2.2 -1.0 0.0
Leg fat-free mass (left) 0.2 0.8 3.2 0.5 -0.5 -0.1 -0.7 0.7 0.2 0.2 1.0 -0.3 -0.5 -0.7 0.6 0.3 -0.9 -0.1 -1.7 -1.2 -1.0 -1.6 -1.8 -1.1
Trunk fat percentage 2.3 9.3 24.9 2.5 -2.9 -0.7 -1.3 -0.2 2.2 -4.2 -3.3 -4.9 -3.1 -4.2 -3.3 -3.7 -2.1 1.2 -4.4 -2.5 0.9 -0.7 -5.0 -3.5
Hand grip strength (right) 1.7 4.6 10.1 -2.7 3.2 1.7 2.4 -1.6 -2.5 0.8 0.9 1.8 0.1 3.0 2.7 2.1 2.3 -1.9 1.4 2.0 -0.9 1.5 3.0 3.1
Townsend deprivation index at recruitment 0.7 1.0 13.0 0.5 -0.4 0.5 -0.1 0.5 0.5 -0.1 0.4 -1.3 -3.6 -0.3 -0.9 -1.4 0.1 0.1 -0.4 0.4 -0.1 -1.3 -0.3 -0.2
Current tobacco smoking 0.2 0.3 1.4 0.5 0.7 0.2 -0.0 0.5 -0.7 0.7 -0.1 0.6 -0.7 -0.4 -0.2 -0.1 -0.3 0.6 -1.2 -0.1 0.8 -0.6 -0.1 -0.8
Average weekly fortified wine intake 0.5 0.5 3.5 -0.5 0.5 -0.0 0.1 0.9 -1.9 0.1 0.4 0.8 0.1 1.0 1.1 0.3 0.4 -0.5 0.8 1.1 -0.1 -0.7 0.5 0.1
Maternal smoking around birth 1.4 2.0 5.9 -0.5 1.2 2.3 2.2 -2.4 -0.5 -1.3 -1.8 -1.7 -0.5 0.2 -0.2 -1.3 1.2 0.0 -2.2 1.5 0.8 1.6 0.6 1.1
Fed-up feelings 0.3 0.5 1.7 0.6 0.2 0.7 0.6 -0.0 0.3 -1.3 -1.1 -0.1 -1.0 1.1 -0.5 -0.5 0.5 0.9 -0.7 0.6 1.3 0.1 -0.9 -0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 7.5 1.6 0.7 1.0 0.7 -0.3 1.2 -1.0 -1.5 -0.4 -1.0 0.2 -0.9 -0.4 0.3 2.0 -1.3 1.6 2.7 0.3 -0.8 -0.5
Relative age voice broke 0.1 0.2 0.9 -0.2 -0.5 -1.0 -0.5 0.6 -0.3 -0.2 0.2 0.6 0.4 -0.3 0.6 0.3 -0.6 0.3 0.2 -0.1 0.0 0.5 0.3 -0.3
Taking other prescription medications 0.7 1.1 5.3 0.0 1.5 2.3 1.5 -0.7 -0.5 -0.4 -0.5 -0.8 -1.8 1.3 -0.2 0.1 1.8 0.8 -0.8 -0.1 0.6 -0.0 0.8 0.2
Age when periods started (menarche) 0.6 1.5 8.7 -0.3 0.7 0.1 -0.1 0.9 -1.4 1.4 2.2 3.0 0.9 2.1 0.6 1.6 1.4 0.1 0.8 -0.3 -0.1 -0.4 1.0 0.2
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 7.4 0.5 1.0 1.2 0.4 -0.1 0.6 0.3 -0.2 -0.6 -0.7 -0.2 -0.3 0.0 0.6 1.4 -2.7 0.0 1.1 -0.1 -0.2 -0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.8 9.9 1.4 -1.2 -0.4 -1.0 -0.0 1.6 -0.8 -0.0 -2.0 -1.4 -1.9 -1.5 -3.1 -1.6 0.7 0.6 1.3 1.4 -0.1 -0.3 -0.6
Tinnitus: Yes, but not now, but have in the past 1.2 1.3 5.2 0.3 0.5 -0.5 -0.6 2.3 -0.1 1.9 1.4 1.4 -1.2 0.6 -0.0 1.1 -0.5 1.1 0.4 -1.8 -0.2 -1.8 0.1 -1.2
Qualifications: CSEs or equivalent 0.1 0.2 0.7 0.5 0.3 -0.7 -0.0 0.5 0.1 0.5 -0.5 0.2 0.5 0.5 0.5 -0.5 0.0 0.5 -0.5 0.6 0.9 0.1 -0.1 -0.2
Serious illness, injury or assault to yourself 1.6 1.9 7.3 -0.7 0.9 1.3 2.0 -2.0 -0.3 -2.7 -2.3 -1.3 -0.7 -0.4 0.9 -0.6 1.7 -0.8 -1.3 1.2 0.1 2.0 0.3 1.3
High blood pressure 1.2 3.3 10.7 -0.9 1.1 3.1 2.2 -2.1 -1.6 -2.8 -3.3 -2.5 -1.9 -1.1 0.6 -0.7 1.8 -1.0 -2.4 1.5 0.2 1.3 0.5 0.7
Hayfever, allergic rhinitis or eczema 0.3 0.6 2.1 0.4 0.5 -0.4 0.6 0.3 -1.0 1.3 -0.6 1.0 -0.2 0.3 0.6 0.2 -1.5 0.5 1.0 0.4 1.3 0.5 1.0 0.1
Multivitamins +/- minerals 0.8 1.0 6.0 -0.2 -1.0 -1.6 -1.3 1.3 -0.2 0.0 0.5 0.3 0.4 1.5 0.4 0.9 -0.8 -0.9 2.4 -0.8 -1.0 -0.9 -0.7 -0.2
Stomach or abdominal pain in last month 1.9 2.3 9.6 -0.1 -0.1 -1.2 -1.2 3.1 -1.0 1.8 1.9 2.9 -0.4 1.8 1.2 2.6 -0.1 0.3 1.9 -0.7 -0.6 -1.9 0.1 -0.7
Supplements: Glucosamine 1.1 1.5 10.4 1.2 -0.2 0.9 -1.1 0.6 0.8 1.8 3.2 1.8 1.0 0.2 -0.6 0.5 -0.1 1.1 0.8 -1.6 -0.2 -1.4 -0.6 -0.9
Diverticular disease/diverticulitis (self-reported) 1.5 1.8 3.8 -1.7 -0.1 0.1 0.2 -0.4 -1.1 0.7 1.3 1.7 1.9 0.4 1.9 1.1 0.3 -1.7 1.9 1.6 -1.8 0.9 1.9 1.8
Medication: Atenolol 0.6 0.8 2.8 -0.3 1.3 1.7 1.2 -0.8 -0.3 -0.4 -0.1 -0.1 1.1 -0.4 1.0 -0.0 0.1 -0.5 -0.1 1.6 0.1 0.6 1.6 0.8
Medication: Levothyroxine sodium 0.9 1.6 14.9 0.5 0.4 1.5 1.2 -1.2 0.3 -1.3 -1.6 -0.7 -0.7 -0.4 -0.7 -0.5 1.4 0.5 -3.9 -0.9 1.2 1.5 -0.2 -0.6
Sitting height 0.3 2.2 11.6 -0.4 -0.1 0.5 0.3 -1.1 -0.2 -1.8 -1.9 -3.0 -0.5 0.1 -0.1 0.3 -0.4 -0.9 -3.4 -2.4 -1.8 -0.2 -2.6 -0.8
Chronic bronchitis/emphysema (father) 1.7 2.0 4.9 -0.6 1.5 2.2 2.2 -1.9 -0.9 -2.1 -1.9 -1.7 -0.4 0.3 0.4 -0.9 2.0 0.1 -0.3 2.1 1.1 1.4 0.6 1.2
High blood pressure (mother) 0.8 1.2 3.5 1.1 -1.7 -1.0 -0.8 -0.1 0.9 -1.9 -1.6 -1.8 -0.6 -1.0 -0.8 -1.8 -1.1 0.0 -0.3 -0.1 0.3 0.0 -1.4 -0.6
Body mass index (BMI) 0.6 2.6 11.2 0.7 -1.7 0.8 0.5 -1.1 0.9 -2.1 -1.6 -2.7 -2.1 -3.4 -0.4 -2.3 -1.1 -0.0 -2.7 0.1 -0.1 0.4 -1.6 -0.7
Impedance of leg (left) 0.6 3.1 15.1 -0.0 0.9 0.6 1.2 -1.8 -0.5 -3.6 -3.9 -2.8 -1.2 0.5 -2.2 -2.0 1.7 0.2 -1.5 0.3 1.6 2.3 -0.7 0.1
Leg predicted mass (left) 0.2 0.8 3.0 0.5 -0.5 0.0 -0.7 0.7 0.2 0.4 1.1 -0.2 -0.5 -0.7 0.6 0.4 -0.9 -0.1 -1.7 -1.2 -1.0 -1.6 -1.7 -1.1
Trunk fat mass 1.5 6.5 19.7 1.8 -2.1 -0.1 -0.7 -0.5 1.5 -3.7 -2.8 -4.2 -2.6 -3.5 -2.4 -3.0 -1.5 0.7 -4.4 -2.1 0.4 -0.6 -4.3 -2.8
Waist circumference 0.6 2.3 10.3 0.8 -1.5 0.6 -0.0 -0.7 0.6 -2.6 -1.4 -2.3 -1.7 -3.2 -0.2 -2.0 -0.5 -0.4 -2.5 0.3 0.0 -0.3 -1.9 -1.0
Number of incorrect matches in round 0.9 1.6 5.8 -1.4 0.2 0.4 1.0 -1.1 -1.3 -0.2 -0.2 1.1 0.4 -0.5 1.6 1.1 0.4 -1.5 2.4 1.5 -1.1 1.5 2.0 1.8
Past tobacco smoking 1.0 1.9 5.6 -0.2 -0.6 -1.8 -0.7 1.4 1.7 2.4 2.2 1.7 2.1 -0.7 1.2 1.0 -1.0 0.2 2.0 0.8 -0.3 -0.2 1.8 0.5
Alcohol usually taken with meals 0.9 1.4 7.9 -1.8 0.4 -0.4 0.5 -1.1 -1.2 0.2 0.1 0.4 2.8 1.6 1.5 1.0 0.7 -1.0 0.9 -0.4 -1.8 0.9 1.2 1.4
Nervous feelings 0.4 0.8 4.2 0.5 -1.1 -1.0 -0.7 0.8 0.4 -1.6 -1.3 -0.3 -2.1 -0.5 -0.7 0.3 -0.9 0.5 0.2 0.2 0.1 -0.1 -1.5 -0.8
Frequency of tenseness / restlessness in last 2 weeks 0.9 1.3 4.8 1.4 -0.1 -1.0 -0.8 1.2 0.8 0.1 -0.6 -0.5 -1.4 1.4 -1.4 -0.8 -1.0 2.1 0.5 1.1 2.2 -1.0 -1.4 -0.9
Hearing difficulty/problems with background noise 1.2 1.9 10.6 2.3 1.0 0.3 -0.1 0.4 1.4 1.6 0.5 1.0 0.3 0.6 -2.0 -0.4 0.0 3.2 0.3 -0.8 2.7 -1.2 -0.5 -1.3
Hair/balding pattern: Pattern 2 0.6 0.7 3.2 -0.4 -1.2 -0.5 -0.1 0.4 -1.1 0.6 0.4 1.8 0.9 0.1 1.2 0.9 -0.5 -0.9 1.6 0.2 -0.3 0.5 0.7 0.7
Had menopause 0.2 0.2 1.3 -0.5 -0.5 0.4 0.2 -0.1 -0.4 -0.3 0.5 0.5 -0.2 -0.1 0.1 0.8 0.5 -0.1 0.4 -0.8 -1.1 -0.1 -0.6 -0.0
Had other major operations 1.6 2.0 4.8 -1.3 2.0 1.7 2.2 -1.6 -1.5 -0.6 -1.2 0.3 0.1 0.6 1.3 0.2 1.9 -0.7 -0.6 2.0 0.6 1.8 2.1 1.7
Forced vital capacity (FVC) 1.0 3.9 12.6 2.0 -1.1 -2.1 -3.1 3.3 -0.5 0.7 0.7 -0.0 -0.2 1.8 -2.4 0.0 -1.8 1.6 0.7 -1.6 1.2 -3.0 -3.5 -3.0
Heel bone mineral density (BMD) T-score, automated (right) 1.8 4.0 14.7 2.3 -2.4 -2.0 -2.3 0.9 2.2 -0.4 0.0 -2.2 -1.6 -3.0 -2.6 -3.8 -3.1 1.4 0.9 0.3 1.3 -1.4 -1.5 -1.7
Ever unenthusiastic/disinterested for a whole week 0.5 0.7 2.8 0.4 -0.8 -0.9 -1.4 1.0 0.2 -0.0 0.6 1.1 0.1 0.1 -0.2 0.8 -0.8 -0.4 1.0 -0.5 -0.4 -1.2 -1.7 -0.7
Qualifications: None of the above 0.3 0.6 2.7 -0.8 -0.4 1.6 0.8 -0.3 -0.7 -0.2 -0.6 -0.7 -0.9 -0.9 0.9 0.1 0.5 -0.1 -1.6 1.0 -0.6 0.4 0.9 0.3
Financial difficulties in last 2 years 1.2 1.6 4.6 1.7 0.1 -0.1 -0.1 -0.3 2.1 -1.6 -1.4 -1.5 -0.3 -1.2 -1.7 -1.4 -0.9 1.7 -1.7 -0.5 1.6 -0.4 -1.6 -1.4
Mouth/teeth dental problems 0.8 1.2 4.4 -1.2 0.8 -0.1 0.7 -1.1 -0.7 -1.2 -0.8 -0.3 2.1 -1.1 1.0 -0.5 0.5 -1.8 0.6 1.7 -0.6 1.2 1.2 1.4
Heart attack 3.8 4.8 13.3 -2.3 2.3 3.2 3.0 -2.6 -2.1 -1.9 -1.4 -0.4 0.8 1.1 2.5 1.7 3.6 -2.3 -2.0 0.6 -2.0 2.3 2.0 2.5
Allergy 0.3 0.6 2.0 -0.5 -0.6 0.4 -0.8 -0.3 0.3 -1.3 0.1 -1.4 0.2 -0.4 -0.9 -0.4 1.0 -0.8 -0.9 -1.1 -1.3 -0.3 -1.0 -0.5
Pain all over the body in last month 0.5 0.5 5.4 0.7 -0.2 0.2 -0.4 0.8 0.3 0.0 0.3 -0.2 -2.3 -0.7 -0.7 -0.4 0.1 0.5 0.8 0.6 0.6 -1.1 -0.3 -0.5
Diabetes (self-reported) 2.4 3.8 10.7 -2.4 2.0 2.4 3.0 -3.3 -1.2 -1.6 -1.4 -1.3 0.9 0.4 1.9 0.4 2.8 -1.6 -1.2 1.2 -1.7 2.5 1.9 2.3
Hayfever/allergic rhinitis (self-reported) 0.8 1.0 4.2 -0.8 0.7 0.5 1.2 -0.2 -1.0 0.2 -0.8 1.5 1.0 1.7 1.4 2.1 0.7 -0.4 0.8 -1.1 -0.3 1.2 0.8 0.6
Medication: Ramipril 2.8 3.5 17.1 -1.9 1.4 4.1 2.6 -2.1 -2.1 -1.8 -0.5 0.4 -0.5 0.8 2.4 1.6 3.0 -1.0 -1.1 0.6 -1.1 2.0 1.8 1.8
Medication: Simvastatin 1.0 1.5 6.0 -1.5 1.4 1.8 0.8 -0.1 -2.5 0.1 1.0 1.3 -0.8 0.7 1.9 1.7 1.5 -0.5 1.1 0.8 -1.1 -0.5 1.3 0.7
Fluid intelligence score 0.4 0.9 4.5 0.9 -0.2 -1.2 -1.1 0.5 1.3 0.9 1.2 0.5 -0.3 0.1 -1.3 -0.1 -1.2 0.7 -0.1 -2.1 0.6 -0.9 -0.7 -1.3
Illnesses of siblings 0.4 0.5 2.6 0.0 -0.8 -1.4 -0.9 0.9 0.6 1.6 0.7 -0.0 0.4 -0.2 -0.4 -0.6 -0.8 -0.1 0.2 0.1 -0.3 -0.8 0.9 -0.1
Neuroticism score 0.6 1.2 5.2 1.4 -0.2 -0.5 -0.5 0.8 0.9 -1.1 -1.3 -0.4 -2.3 0.6 -1.0 -0.4 -0.7 1.7 -1.0 -0.1 1.4 -0.5 -1.8 -1.2
Weight 0.4 2.2 10.8 0.9 -1.1 0.7 0.0 -0.5 0.6 -1.8 -1.1 -2.5 -2.0 -2.2 -0.6 -1.5 -0.7 0.1 -3.3 -1.1 -0.3 -0.6 -2.5 -1.4
Impedance of arm (right) 3.3 15.2 38.1 4.9 -3.1 -3.9 -4.3 2.7 4.1 -2.5 -2.1 -3.9 -1.8 -2.5 -6.2 -3.7 -3.5 4.4 -1.5 -3.7 3.5 -3.0 -6.2 -5.9
Arm fat percentage (right) 2.6 10.3 25.7 3.0 -3.2 -0.9 -1.4 -0.0 3.1 -3.9 -3.2 -5.1 -2.9 -4.9 -3.4 -4.1 -2.7 2.0 -4.0 -2.1 1.6 -1.1 -5.0 -3.7
Trunk fat-free mass 0.4 2.2 7.1 -1.5 1.8 1.7 1.2 -0.4 -1.6 1.2 1.7 1.8 0.6 1.6 2.7 2.6 1.4 -1.3 -0.7 -0.2 -1.7 -0.3 0.8 1.1
Hip circumference 0.6 2.4 9.7 1.3 -1.5 0.4 -0.4 -0.2 1.1 -1.4 -0.8 -2.2 -1.4 -2.5 -0.8 -1.6 -1.5 0.5 -3.1 -1.4 -0.0 -1.0 -2.7 -1.8
Time employed in main current job 0.2 0.3 1.3 -0.0 -0.0 -0.4 -0.4 0.8 -1.0 -0.3 0.0 0.5 0.6 -0.1 0.2 0.2 0.1 -0.5 0.1 -1.1 -0.4 -0.5 -0.7 -0.3
Alcohol intake versus 10 years previously 0.4 0.6 2.6 0.8 -1.6 -1.1 -1.1 0.8 0.8 -0.2 0.7 0.1 0.5 -0.3 -0.5 -0.2 -0.1 -0.9 1.4 0.2 -0.5 -1.1 -0.9 -0.2
Father’s age at death 2.1 2.9 8.6 1.1 -0.9 -2.0 -2.4 2.0 0.4 2.3 2.9 2.1 0.2 0.2 -0.7 1.2 -2.2 0.3 1.7 -2.0 -0.8 -2.7 -1.3 -1.6
Worrier / anxious feelings 0.5 0.9 3.2 -0.4 -0.7 1.0 0.8 -0.6 -0.5 -1.7 -1.7 -0.5 -1.8 -1.1 0.8 0.4 0.3 -0.8 -1.3 0.4 -1.2 1.0 -0.2 0.5
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 5.4 1.1 0.1 -0.4 0.4 0.5 0.6 0.3 -1.1 0.3 -0.4 0.4 -0.1 -0.8 -0.7 1.5 -0.2 2.3 1.5 0.3 0.2 0.3
Falls in the last year 1.3 1.8 5.2 1.9 -1.0 -0.2 -1.4 1.7 1.7 0.8 1.5 0.2 -0.6 0.2 -1.7 -1.0 -0.5 1.6 -0.6 -1.2 1.3 -2.3 -1.8 -1.8
Hair/balding pattern: Pattern 3 3.6 5.4 19.7 3.0 -2.7 -1.7 -2.3 1.0 3.8 0.5 0.6 -2.8 0.3 -2.7 -3.0 -4.4 -2.5 2.5 -0.8 -0.2 1.6 -2.0 -2.0 -2.2
Number of live births 0.5 0.7 3.6 -0.0 0.5 0.3 0.4 0.2 0.0 -0.1 -0.9 -1.3 -1.4 0.6 -0.5 -1.0 0.0 1.1 -1.9 -0.2 1.3 0.6 -0.4 -0.6
Forced expiratory volume in 1-second (FEV1) 1.6 5.3 14.4 2.7 -2.0 -2.8 -3.8 3.6 0.8 0.6 1.1 -0.5 -0.1 0.8 -2.8 -0.6 -2.6 2.0 1.3 -1.7 1.3 -3.2 -3.8 -3.4
Pulse rate 0.4 0.6 2.9 -0.2 -0.2 0.4 0.6 -0.7 1.3 0.4 0.8 -0.6 -0.2 -1.7 0.4 -0.5 0.7 -0.3 0.1 1.5 -0.8 0.1 1.4 1.1
Happiness 1.6 1.9 6.3 1.1 -2.2 -1.9 -2.4 1.4 1.3 -0.5 -0.0 -1.3 0.6 -0.4 -1.6 -0.9 -1.8 0.0 -0.0 -1.6 -0.5 -1.1 -2.5 -1.5
Noisy workplace 2.0 2.4 6.6 -2.0 2.1 1.8 1.9 -0.9 -2.6 -1.4 -2.2 0.6 -1.3 1.5 1.9 2.1 1.4 -1.1 -1.1 0.9 -0.3 1.4 0.5 1.2
Qualifications: A levels/AS levels or equivalent 0.2 0.4 1.8 -0.6 0.0 -0.1 -0.1 -0.4 0.2 -0.0 0.1 0.0 1.2 -0.3 -0.0 -0.6 0.3 -1.4 0.4 0.8 -1.1 0.3 0.2 1.0
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 1.4 0.7 0.0 0.3 0.3 -0.2 0.1 -1.2 -1.0 -0.9 0.8 -0.5 -0.3 -1.0 0.1 0.7 0.2 0.6 0.6 0.4 -0.2 -0.0
Mouth/teeth dental problems: Dentures 0.6 1.1 5.0 -0.7 0.5 1.0 0.3 0.7 -0.9 0.9 1.3 0.7 -1.2 2.2 0.5 2.1 1.1 -0.3 0.5 -1.2 -0.9 -1.0 0.1 -0.2
Asthma 0.5 1.0 3.0 -0.3 1.1 0.5 1.2 0.2 0.2 1.7 1.3 1.2 -0.6 0.9 1.0 1.4 1.3 0.3 1.7 0.4 0.3 -0.4 1.1 0.8
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 3.3 1.2 0.3 0.0 -0.1 -0.8 1.8 -0.4 -0.3 -0.3 -0.0 -0.5 -0.9 -0.9 -0.9 1.3 -1.0 -0.5 1.2 -0.0 -1.1 -0.4
Medication: Cholesterol lowering 1.6 2.5 10.5 -1.1 2.2 2.2 1.7 -1.0 -1.1 1.6 1.2 1.6 1.6 1.1 2.0 1.0 1.7 0.0 0.3 1.9 -0.3 0.5 3.2 1.8
Depression (self-reported) 0.3 0.3 1.0 0.4 -0.2 0.3 -0.2 0.7 -0.4 -0.4 -0.2 -0.1 -1.0 1.0 0.0 0.7 0.2 0.5 0.7 -0.8 0.1 -0.7 -1.0 -0.7
Medication: Lansoprazole 0.6 0.7 2.2 0.3 1.0 0.6 -0.2 1.5 -0.8 0.8 1.0 0.8 -0.5 1.3 -0.3 0.5 0.4 1.0 0.0 0.5 1.2 -1.4 -0.0 -0.7
Prospective memory result 0.3 0.4 2.0 -0.4 0.4 0.2 0.9 -0.6 -0.1 -0.5 -1.0 -0.0 0.0 0.3 0.3 -0.2 0.7 0.0 0.4 1.4 0.4 1.0 0.2 1.1
Lung cancer (father) 0.5 0.5 2.6 0.9 0.5 0.7 0.0 1.0 -0.3 0.6 0.2 0.2 -0.8 -0.7 -0.1 -0.2 -0.2 1.3 -1.6 0.5 1.2 -0.5 -0.6 -0.8
Illnesses of mother 0.3 0.3 1.0 0.1 -0.7 -0.5 -0.5 0.9 0.0 0.6 0.6 0.5 -0.6 -1.0 -0.2 0.5 -0.9 0.0 0.2 -0.6 -0.3 -0.5 -0.1 -0.8
Forced expiratory volume in 1-second (FEV1), Best measure 2.3 7.3 21.3 3.4 -2.4 -3.0 -4.4 3.8 1.4 0.5 0.9 -1.4 -0.5 0.5 -3.5 -1.3 -2.9 2.7 0.8 -2.1 1.6 -3.6 -4.6 -4.1
Pulse wave Arterial Stiffness index 4.7 5.5 13.5 -2.4 1.6 3.3 3.0 -3.7 -1.8 -2.8 -2.8 -2.1 -2.3 -1.2 1.5 -0.2 2.3 -1.9 -1.8 2.9 -1.3 2.7 1.7 2.9
Impedance of arm (left) 2.1 9.7 25.7 3.6 -2.5 -3.3 -3.5 2.2 2.8 -2.4 -2.0 -3.2 -1.6 -1.6 -4.9 -2.6 -2.7 3.4 -1.7 -3.5 2.3 -2.2 -5.1 -4.8
Arm fat mass (right) 1.4 5.7 15.8 2.2 -2.3 -0.2 -0.8 -0.3 2.1 -2.8 -2.2 -3.8 -2.2 -4.0 -2.1 -3.0 -1.9 1.3 -3.6 -1.4 0.9 -0.8 -3.8 -2.6
Trunk predicted mass 0.4 2.4 7.4 -1.5 1.9 1.8 1.3 -0.4 -1.7 1.3 1.7 1.9 0.5 1.8 2.7 2.7 1.5 -1.3 -0.7 -0.2 -1.8 -0.3 0.9 1.2
Standing height 0.2 2.0 7.7 0.1 1.7 0.2 -0.7 1.0 -1.0 0.4 1.1 0.6 -0.2 2.8 -0.2 2.1 1.1 0.3 -1.5 -2.6 -0.6 -2.1 -2.1 -1.5
Length of working week for main job 0.9 1.0 4.0 0.9 -1.0 -2.0 -1.3 1.5 0.6 0.2 0.3 1.5 1.6 -0.2 -0.1 0.2 -1.8 0.1 0.4 -0.9 0.0 -0.7 -1.4 -0.6
Exposure to tobacco smoke at home 1.0 1.1 5.3 0.9 -1.4 -0.7 -0.8 0.4 0.9 -1.1 -1.4 -2.3 0.2 -0.4 -0.7 -0.6 -0.1 0.5 -0.6 -1.6 -0.5 -0.4 -1.7 -1.2
Breastfed as a baby 1.0 1.2 4.9 -1.9 -0.4 -1.1 -0.2 -0.2 -1.4 -0.3 -0.8 -0.9 0.8 0.5 1.0 0.5 -0.2 -2.2 0.5 0.8 -2.2 1.0 0.4 1.6
Tense / ‘highly strung’ 0.4 0.7 4.0 0.2 1.3 0.1 -0.1 0.8 -0.2 0.4 -0.3 0.0 -2.0 1.6 -0.3 0.4 -0.4 1.6 0.3 -0.2 1.3 -0.8 -0.4 -0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.8 1.3 9.5 0.8 0.5 0.6 -0.1 -0.1 -0.9 -1.7 -1.2 -0.6 -3.1 0.5 -1.0 -0.2 -0.3 0.9 -0.8 -0.1 1.4 -0.5 -2.0 -1.2
Hair/balding pattern: Pattern 4 0.6 1.4 4.2 -1.7 2.1 1.2 1.5 -1.3 -0.8 -1.1 -1.4 -0.3 -0.4 1.4 1.3 1.8 1.7 -0.7 -0.3 0.3 -0.1 1.1 0.6 1.1
Birth weight of first child 2.6 4.7 11.2 2.4 -2.1 -2.7 -3.3 3.0 2.0 2.0 2.7 1.5 -0.1 -0.9 -1.7 -0.2 -3.0 1.8 1.7 -1.4 0.7 -3.3 -2.0 -2.6
Peak expiratory flow (PEF) 0.3 0.8 2.6 1.0 -0.0 0.4 -0.9 1.4 0.2 0.3 0.7 -0.3 -0.4 0.6 -0.6 0.6 -0.4 1.2 -0.1 -1.3 0.5 -1.3 -1.6 -1.4
Pulse wave reflection index 1.8 2.2 4.6 -1.9 0.7 1.7 1.7 -1.9 -2.0 -1.4 -2.1 -1.6 -1.6 0.7 1.2 0.3 1.4 -1.4 -1.4 1.0 -1.3 1.7 0.5 1.6
Ever highly irritable/argumentative for 2 days 1.3 1.5 5.8 1.0 0.3 -0.0 -0.6 0.4 -0.6 0.1 -1.3 -2.0 -2.4 -0.3 -1.9 -1.1 -0.7 1.3 -1.1 -1.1 1.3 -1.1 -1.7 -1.8
Loud music exposure frequency 0.3 0.4 1.2 -0.0 0.4 0.6 0.5 -1.0 0.5 -0.7 -1.1 -1.0 -0.6 -0.2 -0.1 0.0 0.5 0.4 -0.9 -1.0 -0.0 0.7 -0.2 -0.1
Qualifications: O levels/GCSEs or equivalent 0.4 0.7 4.3 0.1 1.6 0.4 0.5 -1.3 0.9 -0.4 -0.4 0.4 2.1 -0.1 -0.1 -0.4 -0.0 -0.1 -0.1 0.8 1.2 1.2 0.4 0.7
Mouth/teeth dental problems: Bleeding gums 1.2 1.5 3.9 1.9 -0.8 -0.6 -0.8 -0.1 1.7 0.2 -0.3 -0.5 0.1 -1.0 -1.8 -1.2 -1.3 1.9 -1.3 -2.0 1.2 -0.2 -1.9 -1.3
Blood clot in the leg (DVT) 0.6 0.8 3.7 0.4 -0.8 -1.5 -1.3 0.8 0.4 0.7 1.1 0.2 0.9 0.3 0.1 0.1 -1.9 0.6 -0.2 -1.4 -0.5 -0.9 -0.8 -0.9
Medication: Paracetamol 0.5 0.8 4.4 -0.6 0.6 1.2 0.8 0.3 -1.3 -0.6 -0.5 1.0 -0.1 2.1 1.4 1.6 1.0 0.0 -0.7 0.2 0.0 0.3 -0.5 0.5
Headache pain in last month 0.5 0.9 3.6 0.5 0.8 -0.0 -0.3 1.9 -0.5 1.1 1.4 1.6 -1.2 0.9 0.3 0.3 0.1 0.8 0.2 0.5 1.1 -1.8 -0.1 -0.8
Medication for cholesterol, blood pressure or diabetes 0.8 1.4 5.8 1.2 -1.4 -2.4 -1.4 1.2 1.3 -0.4 0.1 -0.2 -1.4 0.1 -1.8 -0.9 -1.3 0.3 1.2 -0.6 1.0 -0.5 -1.8 -1.0
Glaucoma (self-reported) 0.7 0.9 7.6 0.3 -0.6 0.1 0.2 -0.7 0.8 0.6 0.4 0.2 0.1 -1.8 -0.0 -0.6 -0.2 0.5 1.0 2.8 0.6 0.5 1.5 0.8
Gout (self-reported) 1.5 2.0 5.4 -1.6 2.3 2.0 2.0 -1.6 -2.1 -0.5 -0.9 0.6 0.2 0.8 1.7 0.2 0.7 -1.3 -0.9 1.6 -0.2 1.8 1.1 2.1
Hypothyroidism/myxoedema (self-reported) 1.1 2.1 12.8 -0.5 0.6 1.7 1.6 -2.0 -0.5 -2.4 -2.2 -1.4 -0.3 -0.6 0.2 -0.6 1.1 -0.3 -3.6 0.2 0.1 2.5 0.0 0.5
Medication: Amlodipine 0.8 1.1 4.7 -0.3 0.8 1.1 0.6 0.0 -1.0 1.3 1.6 2.2 0.6 -0.1 1.2 0.6 1.0 0.1 0.5 1.8 0.4 -0.3 1.7 0.5
Medication: Ventolin 100micrograms inhaler 1.2 1.6 6.7 -1.9 1.6 0.1 0.8 -0.4 -2.0 0.5 -0.1 1.5 0.4 2.6 1.5 2.0 0.8 -1.4 0.9 0.2 -0.9 0.4 0.5 1.1
Birth weight 4.6 10.1 25.7 3.7 -2.4 -4.1 -4.4 4.6 2.4 3.2 2.9 0.0 -1.2 -0.3 -3.3 -2.0 -3.5 3.6 0.9 -2.8 2.4 -5.1 -2.6 -4.7
Chronic bronchitis/emphysema (mother) 0.8 0.9 3.2 -0.6 1.5 1.8 1.5 -1.3 -0.0 -0.3 -0.1 -0.4 -1.0 1.2 0.1 -0.1 1.6 -0.5 -1.1 0.0 -0.7 0.5 0.8 1.0
High blood pressure (siblings) 0.3 0.5 2.2 -0.3 0.4 1.1 0.6 -1.0 -0.6 -1.5 -0.8 -1.1 -0.6 0.1 0.5 -0.6 0.6 -0.4 -0.1 0.9 -0.1 0.7 -0.2 0.7
Forced vital capacity (FVC), Best measure 1.5 5.4 18.7 2.6 -1.4 -2.5 -3.8 3.2 0.5 0.6 0.6 -1.1 -0.7 1.4 -3.1 -0.8 -2.4 2.2 0.6 -1.7 1.4 -3.4 -4.3 -3.4
Body fat percentage 2.4 9.3 29.5 2.1 -2.8 -0.2 -0.6 -0.9 2.1 -4.8 -3.8 -5.4 -3.2 -4.3 -3.0 -3.9 -1.7 0.8 -4.6 -2.1 0.7 -0.1 -4.6 -2.9
Leg fat percentage (right) 2.0 7.1 28.6 0.9 -1.7 1.1 1.1 -2.3 1.0 -5.1 -4.2 -5.3 -3.0 -3.7 -2.0 -3.9 -0.3 -0.1 -3.5 -0.1 0.6 1.4 -2.8 -0.9
Arm fat-free mass (right) 0.8 3.9 10.8 -2.5 2.1 2.6 2.4 -1.5 -2.7 0.7 0.9 1.5 0.2 1.6 3.3 2.5 2.2 -2.4 -1.2 0.5 -2.3 1.0 1.8 2.2
Exposure to tobacco smoke outside home 0.7 1.0 2.9 0.8 -1.1 -1.6 -1.4 1.7 0.3 0.9 0.7 0.1 -1.3 -0.7 -0.8 -0.9 -1.2 0.8 0.3 -0.7 0.4 -1.1 -0.9 -1.2
Comparative body size at age 10 0.2 0.5 1.5 -0.0 -0.9 -0.9 -1.1 1.1 -1.2 0.6 0.4 0.4 0.1 -0.2 -0.2 -0.2 -0.9 -1.1 0.9 0.3 -0.7 -1.0 -0.1 -0.2
Number of full brothers 1.4 1.8 4.7 1.7 -0.1 -0.9 -1.2 1.9 1.5 1.9 1.9 1.2 0.1 1.0 -0.7 0.3 -1.3 2.0 0.7 -0.5 1.5 -2.2 -1.0 -1.5
Worry too long after embarrassment 0.5 0.8 3.9 1.0 0.4 -0.2 -0.0 1.0 1.0 0.7 -0.0 0.5 -2.0 0.5 -0.2 0.3 -0.2 1.9 -0.5 0.5 1.9 -0.3 -0.1 -0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.8 2.3 0.9 0.6 -0.1 -0.6 0.8 -1.3 0.4 0.5 0.7 -1.5 0.5 -0.7 0.3 -0.1 1.4 -0.2 -0.8 1.2 -1.2 -0.8 -1.4
Wheeze or whistling in the chest in last year 0.5 1.0 3.9 -0.5 1.6 1.4 0.6 0.3 -1.2 1.1 1.1 0.9 -2.0 1.6 0.4 0.4 1.1 -0.4 -0.2 0.7 0.5 -0.9 0.1 0.3
Number of children fathered 1.0 1.1 3.6 -0.7 0.9 1.9 1.4 -1.9 -0.3 -0.6 -1.2 -0.0 0.5 -1.1 0.2 0.4 0.5 -0.7 -1.6 -0.4 -0.8 1.8 0.8 0.9
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.6 3.0 -0.3 1.4 0.8 0.6 -0.5 -0.6 1.0 0.2 1.7 0.0 -0.5 0.5 1.0 -0.1 -0.0 -0.4 0.7 0.4 0.1 1.3 0.6
Age at first live birth 0.9 1.6 5.5 -1.3 -0.6 -1.7 -0.5 -0.2 -1.0 1.1 0.5 1.2 2.3 0.8 1.8 1.0 -0.4 -1.5 2.0 1.2 -1.7 0.8 1.1 1.6
Pulse wave peak to peak time 5.0 5.9 14.9 2.5 -1.6 -3.4 -3.1 3.9 1.9 2.8 2.9 2.2 2.0 1.4 -1.6 0.4 -2.2 2.0 1.8 -3.2 1.4 -2.9 -1.8 -3.0
Health satisfaction 0.8 1.0 2.7 0.0 0.6 1.6 1.5 -1.6 -0.0 -1.3 -1.2 -0.6 -0.3 -1.1 -0.1 -0.8 0.7 -0.0 -1.1 1.5 0.7 1.6 0.3 0.7
Shortness of breath walking on level ground 0.4 0.4 1.7 -0.4 0.6 1.3 0.9 -0.2 -1.3 0.4 0.8 0.9 0.2 -0.1 1.2 0.7 0.4 -0.4 -0.3 0.1 -0.3 0.3 0.4 0.1
Qualifications: College or University degree 0.3 0.9 5.9 -0.7 -0.1 -1.1 0.1 -0.1 0.1 0.4 0.7 1.4 1.0 0.3 0.8 1.6 0.2 -0.8 2.4 -0.8 -1.7 0.1 0.0 0.9
Eye problems/disorders: None of the above 0.4 0.5 1.6 -0.6 0.0 -0.8 -0.2 0.7 -0.5 -0.8 -1.1 0.1 -0.4 0.2 0.4 1.0 -0.3 -1.3 -0.6 -1.1 -0.7 -0.4 -0.9 -0.3
Mouth/teeth dental problems: Loose teeth 0.4 0.5 2.4 0.6 -0.0 0.7 0.1 -1.3 0.5 0.1 -0.2 -1.5 -0.8 -1.0 -0.8 -1.2 -0.8 0.7 -1.0 0.0 0.4 0.2 -0.5 -0.1
Emphysema/chronic bronchitis 0.7 0.8 5.6 0.6 -0.6 -1.3 -0.7 1.2 -0.4 -0.6 -0.1 0.5 0.5 0.2 -0.1 -1.1 -0.2 -0.0 1.7 2.4 1.2 -0.4 -0.2 0.0
Medication for pain relief, constipation, heartburn 0.2 0.3 2.2 -0.0 -0.4 -1.5 -0.5 -0.1 0.9 0.6 0.1 -0.6 0.5 -0.9 -0.5 -0.4 -0.8 -0.5 0.3 -0.3 -0.1 0.4 0.5 -0.2
Neck or shoulder pain in last month 0.8 1.2 2.5 -1.2 1.5 1.6 1.6 -0.5 -1.5 -0.3 -0.2 0.5 -1.5 1.5 1.0 1.4 1.2 -0.8 0.5 1.0 -0.5 0.3 0.3 1.3
Medication: Blood pressure 0.6 1.1 6.4 -0.8 1.3 2.5 1.1 -0.8 -1.5 -0.4 -0.4 -0.3 0.8 -0.4 1.4 0.8 1.4 -0.3 -1.6 0.2 -0.8 0.1 0.9 0.5
Angina (self-reported) 0.6 0.8 5.2 -0.3 0.4 1.0 0.3 0.3 -0.3 -0.7 0.4 1.3 2.3 0.9 1.5 1.8 1.0 -0.1 -0.0 0.1 -0.1 0.2 -0.1 0.1
Migraine (self-reported) 1.7 2.1 6.0 2.1 -0.5 -0.6 -1.4 1.2 1.8 -0.3 0.4 -0.8 -2.2 -0.4 -2.2 -1.7 -1.0 2.0 0.8 0.5 2.5 -1.5 -1.5 -1.7
Medication: Ibuprofen 1.0 1.2 4.6 1.8 -0.4 -0.3 -0.5 -0.4 2.1 -0.6 -0.3 -0.6 0.5 -0.8 -1.3 -1.1 -1.4 1.7 -0.5 -1.1 1.3 -0.2 -1.6 -1.0
Medication: Allopurinol 1.9 2.5 6.9 -1.7 2.6 2.2 2.1 -1.2 -2.5 0.1 -0.3 1.2 0.3 1.9 1.9 0.8 1.4 -1.0 -0.8 1.7 0.1 1.5 1.7 2.0
Medication: Omeprazole 4.7 5.6 12.8 -2.7 2.6 2.3 2.2 -0.8 -3.4 0.9 1.0 3.0 1.3 2.9 3.6 3.2 3.2 -1.8 0.7 2.1 -1.3 1.0 2.7 2.8
Medication: Seretide 50 evohaler 0.6 0.7 3.7 -0.1 0.6 0.5 0.9 0.6 -0.1 0.6 0.7 1.0 -1.0 0.5 0.2 1.1 1.9 -0.1 1.8 0.4 0.0 -0.2 1.2 0.5
Mean time to correctly identify matches 1.5 2.9 10.0 -2.0 -1.7 -1.1 -0.5 0.5 -1.5 0.4 1.8 2.3 2.1 0.3 2.3 2.1 0.0 -2.9 2.3 0.1 -3.2 0.2 1.0 1.4
Heart disease (mother) 0.3 0.4 2.0 -0.0 -0.0 0.1 -0.2 -0.7 -0.4 -1.3 -1.4 -1.4 -0.3 -0.0 -0.0 -0.3 -0.5 -0.4 -0.1 0.2 -0.3 0.3 -1.2 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 2.5 -0.2 1.1 0.2 0.8 0.1 -1.6 0.7 -0.1 1.4 0.7 0.6 0.3 0.8 0.7 0.3 1.1 0.0 1.2 0.2 0.8 0.2
Whole body fat mass 1.4 5.8 19.6 1.4 -1.8 0.5 -0.1 -1.1 1.2 -3.8 -2.9 -4.3 -2.8 -3.5 -1.8 -2.8 -1.1 0.3 -4.4 -1.7 0.1 -0.1 -3.8 -2.1
Leg fat mass (right) 1.2 4.7 18.5 0.7 -1.1 1.2 0.9 -1.8 0.7 -3.7 -3.1 -4.3 -2.5 -3.1 -1.4 -3.0 -0.2 -0.1 -3.9 -0.5 0.2 0.6 -2.6 -1.0
Arm predicted mass (right) 0.7 3.5 9.7 -2.2 1.9 2.5 2.1 -1.2 -2.6 0.9 1.2 1.5 0.2 1.7 3.1 2.4 2.1 -2.2 -1.1 0.3 -2.3 0.8 1.6 2.0
Pulse rate, automated reading 0.2 0.7 2.0 -0.9 -0.5 0.2 1.0 -0.8 0.4 -0.5 -0.5 -1.3 0.4 -0.6 1.0 -0.6 1.4 -0.5 -0.4 1.3 -0.6 1.2 0.7 1.4
Alcohol intake frequency. 0.7 1.5 5.2 1.2 -1.7 -2.2 -1.4 1.9 1.7 0.8 0.6 -0.8 -0.6 -0.1 -0.6 -1.1 -1.2 1.1 2.3 0.5 0.5 -1.4 -0.4 -0.8
Comparative height size at age 10 0.2 1.0 4.6 0.3 0.7 0.3 -0.2 0.8 -0.2 0.0 0.5 -0.0 -2.1 1.5 -0.7 1.2 0.2 0.4 -0.2 -1.4 -0.4 -2.0 -1.4 -1.2
Number of full sisters 0.3 0.4 2.1 -0.6 0.9 -0.2 0.3 0.2 -0.9 -0.1 -0.5 0.1 -0.2 0.4 1.2 0.0 -0.5 -0.2 0.3 1.5 -0.0 -0.2 0.8 0.8
Suffer from ‘nerves’ 1.0 1.5 5.2 1.3 -0.9 -0.9 -1.6 1.9 0.6 -1.0 -0.1 -0.4 -1.9 0.4 -1.3 -0.5 -1.1 1.4 -0.1 -0.4 0.9 -1.6 -2.3 -1.9
Overall health rating 0.5 1.0 5.5 0.2 0.9 1.5 1.4 -0.4 -0.5 -1.3 -1.3 -0.5 -2.3 0.2 0.2 -0.7 1.1 0.6 -0.9 1.3 1.3 0.6 0.2 0.4
Chest pain or discomfort 1.3 1.9 6.6 -0.5 1.5 0.9 0.5 0.8 -1.3 1.8 1.7 2.5 1.3 2.6 1.2 2.0 1.7 -0.0 1.2 1.2 0.7 -0.6 0.9 0.8
Had major operations 0.2 0.2 1.0 0.4 0.6 0.5 -0.1 -0.0 -0.2 0.2 -0.6 -0.4 -0.3 0.2 -0.7 -0.0 -0.0 0.4 -1.0 -0.9 0.2 0.2 -0.2 -0.2
Age at last live birth 1.6 2.3 8.6 -0.1 -1.4 -2.8 -1.8 1.4 0.3 1.9 2.2 1.5 2.9 1.6 0.6 0.5 -0.4 0.0 2.9 0.3 -0.7 -0.9 -0.1 0.3
Family relationship satisfaction 2.5 3.1 7.4 2.2 -1.9 -2.3 -2.1 1.3 2.7 0.3 0.9 -0.9 -0.4 -0.5 -2.6 -0.9 -1.3 1.4 1.0 -2.3 0.1 -2.3 -2.7 -2.3
Leg pain on walking 0.5 0.7 2.2 -0.5 0.5 0.2 -0.3 0.8 -0.3 0.8 1.3 1.0 -1.4 0.3 0.7 1.5 -0.2 0.1 0.8 1.1 -0.5 -1.5 -0.6 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 2.0 0.2 0.5 0.5 0.2 0.6 -0.6 0.3 0.6 0.6 -0.9 0.2 0.0 0.2 0.6 -0.0 1.4 0.6 0.9 -0.4 0.6 0.2
Commuting to job workplace: Car/motor vehicle 0.2 0.2 1.1 0.0 -0.4 -1.0 -0.4 0.7 0.0 -0.3 -0.8 -0.1 0.8 0.2 0.0 0.1 -0.3 0.6 0.3 1.1 0.4 0.1 -0.4 -0.3
Illness, injury, bereavement, stress in last 2 years 1.0 1.2 2.7 -0.2 -1.3 -1.4 -1.6 1.2 -0.8 1.6 1.6 1.4 0.7 0.4 0.0 1.0 -0.7 -0.6 1.6 -1.6 -1.1 -1.0 -0.5 -0.6
Medication: Aspirin 0.2 0.2 2.0 0.1 -0.4 0.8 -0.1 0.3 -0.2 -1.4 -0.1 -0.7 -0.1 -0.2 -0.1 -0.2 0.7 0.2 0.3 0.1 -0.4 -0.4 -0.5 -0.3
Supplements: Vitamin C 1.2 1.4 3.9 -1.5 0.6 0.6 1.0 -1.0 -0.5 0.4 0.8 1.0 1.4 -0.1 1.9 1.2 1.1 -1.2 0.6 1.3 -1.5 1.2 1.9 2.0
Knee pain experienced in last month 0.3 0.5 1.8 -0.6 -0.1 1.1 0.6 -0.8 -0.6 -1.2 -0.8 -0.6 -1.3 0.3 0.5 0.0 0.2 -0.7 -1.2 0.4 -0.4 0.4 -0.6 0.3
Hypertension (Self-reported) 0.9 2.5 9.3 -0.6 0.7 3.0 2.0 -1.8 -1.4 -2.3 -2.8 -2.1 -1.3 -1.1 0.6 -0.6 1.5 -0.7 -2.6 1.2 0.4 1.1 0.5 0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 4.0 4.7 13.1 -2.3 3.6 2.7 2.0 -0.8 -2.8 1.9 1.3 2.7 0.9 2.8 2.7 2.3 2.5 -1.0 -0.5 2.0 -0.6 0.4 3.0 2.3
Illnesses of father: Heart disease 0.8 1.1 5.8 0.7 -1.2 -0.3 -1.3 1.2 -0.1 -0.9 -0.1 -0.5 -1.3 0.4 -1.2 0.5 -0.1 0.5 1.0 -1.8 0.3 -1.2 -2.4 -1.5
Illnesses of siblings: Diabetes 0.7 0.9 2.0 1.1 -0.5 -1.1 -1.4 0.6 1.4 0.5 0.9 -0.3 -0.9 -0.1 -1.3 -0.8 -1.1 1.2 0.7 -0.3 0.9 -1.0 -1.2 -1.0
Smoking status: Previous 1.0 1.5 5.0 0.3 0.2 1.3 0.2 -1.0 -1.2 -2.2 -1.7 -1.8 -2.2 0.9 -1.5 -1.1 0.5 0.2 -1.2 -0.9 0.6 0.1 -1.9 -0.7
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.2 7.6 -0.8 2.8 2.0 1.8 -0.9 -2.5 -0.0 -0.8 0.6 -0.5 1.7 1.2 0.4 1.8 -0.1 -1.7 2.0 1.3 1.5 1.4 1.2
Whole body fat-free mass 0.2 1.2 4.5 -0.9 1.0 1.1 0.6 0.0 -1.0 1.0 1.5 1.2 0.2 0.9 2.1 1.9 0.6 -1.0 -1.1 -0.6 -1.6 -0.7 -0.0 0.4
Leg fat-free mass (right) 0.2 0.8 3.2 0.5 -0.4 -0.4 -0.9 1.0 0.3 1.0 1.5 0.3 -0.3 -0.3 0.9 0.6 -1.0 0.0 -1.2 -1.0 -0.9 -1.8 -1.4 -1.0
Arm fat percentage (left) 2.2 8.8 22.8 2.7 -2.9 -0.7 -1.1 -0.1 2.6 -3.7 -3.0 -4.8 -2.8 -4.6 -3.0 -3.8 -2.4 1.8 -4.0 -1.9 1.3 -0.8 -4.5 -3.3
Average weekly red wine intake 0.9 1.4 4.6 -1.6 0.3 0.9 0.9 -1.1 -2.2 0.6 0.8 1.2 1.5 0.7 1.3 0.4 1.2 -1.5 0.5 1.0 -0.7 1.0 1.8 1.5
Handedness (chirality/laterality): Left-handed 0.2 0.2 0.8 0.1 0.7 0.4 -0.2 0.7 -0.3 0.9 0.6 0.7 0.1 0.9 0.3 0.2 0.2 0.8 -0.2 0.3 0.4 -0.4 -0.4 -0.3
Mood swings 0.8 1.4 4.1 1.8 -0.8 -0.6 -0.8 0.8 1.0 -0.0 -0.5 0.1 -1.1 -0.3 -1.3 -1.1 -1.7 1.9 -0.8 -0.3 2.0 -1.0 -1.7 -1.5
Loneliness, isolation 0.9 1.3 7.2 0.2 0.3 -0.6 0.5 -0.9 0.2 -2.2 -2.7 -1.4 -2.0 -0.0 -0.4 -1.1 -0.4 0.0 -0.1 1.7 1.0 1.0 -0.6 0.4
Long-standing illness, disability or infirmity 0.9 1.3 7.6 -0.4 1.8 2.8 2.0 -0.9 -0.7 -0.3 -0.1 -0.4 -1.7 -0.2 0.4 0.6 2.2 0.7 -0.7 0.0 -0.0 0.3 1.1 0.5
Ever had bowel cancer screening 0.5 0.6 2.1 0.7 -0.8 0.2 -0.7 0.6 1.0 0.4 1.5 0.9 -0.1 0.3 -0.3 1.1 0.2 0.7 -0.9 -1.3 0.2 -0.8 -0.8 -1.1
Diabetes diagnosed by doctor 2.3 3.8 8.9 -2.8 1.4 2.0 2.6 -3.0 -1.6 -1.9 -1.4 -1.3 1.3 0.7 2.1 0.7 2.6 -2.4 -0.9 0.7 -2.6 2.4 1.5 2.3
Ever had stillbirth, spontaneous miscarriage or termination 1.2 1.3 3.7 -0.7 0.9 0.6 0.8 -0.7 -0.1 0.5 0.9 1.8 1.9 0.7 1.5 0.7 1.4 -0.5 1.2 1.7 0.2 0.8 1.7 1.7
Friendships satisfaction 2.0 2.4 8.5 1.3 -2.2 -2.5 -2.7 1.7 1.1 -0.4 -0.0 -0.7 -0.2 -0.0 -2.0 -0.4 -1.7 0.3 0.5 -2.0 -0.3 -1.8 -2.9 -1.8
Qualifications: nursing, teaching 0.3 0.5 1.7 0.1 0.8 1.0 0.5 -0.6 1.3 0.5 0.6 0.3 0.6 1.2 -0.2 0.6 0.9 0.6 0.0 -1.1 -0.1 0.3 0.1 0.3
Commuting to job workplace: Walk 0.4 0.4 2.7 0.8 0.5 0.5 -0.3 0.5 0.4 1.2 1.6 0.8 -0.4 -0.0 -0.4 0.1 0.0 0.6 -0.4 -0.9 0.4 -0.8 -0.1 -0.6
Eye problems/disorders: Cataract 0.6 0.7 2.6 0.3 1.1 1.3 0.8 -0.9 0.5 1.3 1.6 0.8 0.8 -0.1 -0.1 -0.2 1.0 1.0 -0.1 -0.5 -0.1 0.1 1.1 0.2
Mouth/teeth dental problems: Mouth ulcers 0.9 1.4 4.2 1.4 -0.4 -0.4 -1.0 1.7 0.8 1.5 0.8 0.2 -2.0 -0.1 -1.1 -0.4 -1.2 2.0 -0.5 -1.0 0.9 -1.7 -0.9 -1.7
Medication for cholesterol 1.5 2.3 9.6 0.9 0.4 -1.9 -1.7 1.3 1.2 3.1 2.6 1.9 2.7 0.3 -0.4 0.3 -1.5 0.8 2.0 -0.5 0.0 -1.3 0.5 -0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.4 2.9 9.7 -0.9 1.7 2.7 2.3 -1.3 -1.2 0.7 0.5 2.4 0.5 0.2 1.7 1.1 2.3 -0.5 -0.3 3.1 1.0 1.2 2.6 2.2
Back pain experienced in last month 0.4 0.6 4.3 1.1 0.8 0.7 0.5 -0.1 0.6 0.0 0.5 0.9 -0.0 0.0 -0.2 -0.2 -0.0 1.6 0.2 1.0 2.1 -0.1 -0.3 -0.3
Mineral and other dietary supplements 1.0 1.4 4.0 1.0 -0.2 -1.5 -0.3 0.3 0.4 -0.6 -1.6 -1.5 -1.1 -1.1 -1.1 -1.8 -1.5 1.6 -0.9 0.3 2.0 -0.4 -1.2 -1.4
Breast cancer (self-reported) 0.9 1.1 4.3 -0.1 0.8 -0.8 -0.9 0.9 -0.2 2.1 2.0 1.2 1.9 2.0 -0.2 0.1 -0.3 -0.2 1.3 0.0 0.4 -0.8 0.7 0.2
Asthma (self-reported) 0.6 1.1 3.2 -0.4 1.2 0.6 1.2 0.3 -0.1 1.8 1.4 1.2 -0.7 1.3 1.1 1.7 1.4 0.2 1.6 0.2 0.1 -0.6 1.0 0.8
Osteoporosis (self-reported) 1.3 1.6 6.6 -1.3 1.7 1.4 1.8 -0.6 -0.3 0.4 0.3 1.3 -0.6 2.6 1.2 1.9 2.0 -0.1 0.2 -0.3 -0.6 0.8 1.6 1.3
Osteoarthritis (self-reported) 0.5 0.6 3.2 0.0 1.5 1.8 0.8 -0.4 -0.6 0.2 0.6 1.0 -0.7 0.0 0.1 1.1 1.2 0.7 -1.1 -0.1 0.2 -0.7 0.1 -0.2
Medication: Aspirin 0.3 0.4 3.0 -0.0 -0.0 1.3 0.6 -0.3 -0.3 -1.7 -0.6 -0.7 -0.2 -0.2 0.2 -0.3 1.2 0.3 0.2 0.8 0.0 0.3 -0.0 0.1
Medication: Gliclazide 1.3 1.5 7.1 -0.8 2.7 2.0 1.9 -1.9 -1.1 -0.6 -0.6 -0.4 -0.3 0.4 0.4 0.4 2.5 -0.2 -0.6 1.0 -0.1 0.6 1.1 1.1
Illnesses of father: None of the above (group 1) 0.5 0.6 3.1 0.1 -0.6 -1.8 -0.4 0.2 0.6 1.2 0.7 1.0 1.3 -0.3 0.3 -0.7 -0.9 -0.2 0.1 1.1 -0.5 0.1 0.8 0.6
Smoking status: Current 0.2 0.3 0.9 0.6 0.2 -0.3 -0.4 0.7 -0.6 0.6 -0.0 0.8 -0.0 -0.6 -0.2 -0.0 -0.4 0.4 -0.9 -0.4 0.6 -0.6 -0.4 -1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.3 2.7 7.7 2.1 -1.6 -1.9 -2.8 2.1 0.7 0.4 1.2 0.7 0.6 -0.2 -1.7 -0.3 -2.0 2.0 1.9 -0.7 1.3 -1.9 -2.3 -2.3
Whole body water mass 0.2 1.3 5.1 -1.0 1.0 1.2 0.6 0.0 -1.2 1.2 1.7 1.4 0.3 1.0 2.2 2.1 0.7 -1.1 -0.9 -0.6 -1.7 -0.8 0.1 0.5
Leg predicted mass (right) 0.2 0.9 3.5 0.5 -0.4 -0.4 -1.0 1.1 0.4 1.1 1.6 0.3 -0.3 -0.4 0.9 0.6 -1.1 0.1 -1.1 -1.0 -0.9 -1.9 -1.4 -1.0
Arm fat mass (left) 1.2 4.7 13.5 1.7 -1.9 0.1 -0.5 -0.3 1.5 -2.8 -2.2 -3.6 -2.4 -3.6 -1.7 -2.6 -1.7 1.0 -3.7 -1.3 0.6 -0.6 -3.4 -2.3
Number of self-reported non-cancer illnesses 2.0 3.4 13.0 -1.1 2.8 3.6 3.1 -2.8 -1.0 -1.5 -2.0 -0.8 -0.5 0.8 1.2 0.5 2.6 0.1 -2.4 0.9 0.1 1.9 1.2 1.7
Average weekly champagne plus white wine intake 0.3 0.4 2.4 0.6 -0.6 -1.1 -0.9 0.5 -0.2 0.7 -0.1 0.6 0.6 -0.4 -0.7 -0.7 -1.5 0.8 -0.5 -0.2 0.4 -0.1 -0.7 -0.3
Miserableness 0.5 0.9 3.8 1.2 1.2 0.3 0.2 0.5 0.8 1.0 0.7 1.1 -0.8 0.9 0.1 -0.3 -0.6 2.0 -0.6 0.7 2.0 -0.8 0.0 -0.7
Guilty feelings 0.6 1.0 4.3 1.2 0.7 -0.1 -0.1 0.2 0.7 -0.6 -1.2 -1.3 -1.5 0.2 -0.9 -0.4 0.3 2.1 -0.6 0.1 1.9 -0.2 -1.3 -1.0
Wears glasses or contact lenses 0.4 0.5 2.0 -0.8 -0.6 -0.1 -0.1 -0.1 -0.7 -0.6 -0.3 0.1 -0.9 -0.0 0.1 1.2 -0.3 -1.2 0.2 -1.3 -1.4 -0.5 -0.6 -0.2
Ever taken oral contraceptive pill 0.5 0.5 2.6 0.7 0.5 0.3 0.7 -0.2 1.3 -0.5 -0.4 -0.3 1.6 -1.4 -0.3 -0.2 0.8 0.4 -0.8 -0.2 1.1 0.5 0.2 -0.4
Hearing aid user 0.3 0.4 1.7 -0.5 0.1 -0.5 0.0 -0.1 -1.0 0.2 -1.1 0.3 1.3 0.2 0.5 0.3 -0.2 -1.0 -0.2 0.8 -0.4 0.7 -0.1 0.7
Mother’s age at death 0.7 0.8 4.9 -0.9 0.0 -0.3 -0.2 -0.0 0.1 -0.1 0.5 0.0 0.6 1.2 0.6 1.7 0.8 -1.1 -0.1 -1.9 -2.2 -0.3 0.3 0.2
Financial situation satisfaction 2.5 3.0 9.2 1.6 -3.0 -2.0 -1.9 0.5 1.4 -2.4 -1.9 -2.8 -0.1 -1.4 -2.2 -3.0 -1.5 0.2 0.3 -0.3 0.3 -0.0 -2.4 -1.0
Tinnitus: Yes, now most or all of the time 0.4 0.5 2.3 0.0 -0.9 -1.0 -0.7 0.2 0.3 -1.0 -0.9 -0.2 0.6 -0.7 0.0 0.6 -1.0 -0.3 1.5 1.0 0.4 -0.1 -1.1 -0.2
Commuting to job workplace: Public transport 0.3 0.3 2.1 -0.0 -0.0 0.4 0.3 -0.7 0.5 -0.9 0.4 0.2 -0.6 -1.5 0.2 -0.5 0.2 -0.8 0.2 -0.1 -0.6 0.5 0.5 0.5
Eye problems/disorders: Glaucoma 0.7 0.8 6.2 0.0 -0.7 -0.1 0.2 -1.2 0.5 -0.6 -0.5 -0.9 0.9 -1.4 -0.0 -0.8 -0.1 -0.3 0.4 2.5 0.2 0.9 1.1 0.9
Medication: Blood pressure 2.0 3.7 13.3 -1.2 0.1 2.9 2.4 -2.7 -1.1 -3.6 -3.1 -2.6 -2.6 -0.6 0.6 -0.8 1.6 -1.2 -2.1 1.4 -0.2 2.1 0.1 1.2
Pain type(s) experienced in last month: Hip pain 0.3 0.4 2.0 -0.3 1.1 0.7 0.4 0.5 -0.8 -0.1 0.3 0.2 -1.4 0.3 0.5 0.4 0.4 0.9 -0.3 0.8 0.2 -0.8 -0.7 -0.2
Supplements: Fish oil (including cod liver oil) 1.2 1.5 5.9 -1.2 -0.9 0.9 0.2 0.1 0.0 0.1 1.1 0.8 1.5 0.5 1.7 2.0 1.2 -2.0 1.6 -0.2 -2.4 0.5 1.2 1.5
High cholesterol (Self-reported) 0.6 1.0 5.5 -1.3 0.6 0.7 -0.0 0.6 -2.3 0.0 0.2 0.6 -1.4 1.6 1.1 1.7 0.4 -0.3 0.7 -0.3 -1.2 -0.8 0.0 -0.0
Medication: Bendroflumethiazide 0.8 1.2 4.8 0.2 -0.6 0.9 0.7 -1.0 -0.5 -1.6 -2.2 -1.9 -1.6 -1.3 -0.9 -1.8 0.3 -0.1 -0.5 1.5 0.8 0.5 0.0 0.3
Medication: Paracetamol 0.5 0.8 4.4 -0.3 0.8 1.4 0.7 0.3 -1.4 -0.2 0.1 1.4 0.5 2.1 1.2 1.4 1.1 0.1 -0.1 0.4 0.3 0.1 -0.1 0.4
Medication: Lisinopril 0.8 1.0 5.7 0.1 1.3 2.2 0.6 -0.7 -0.7 -0.8 -0.3 -1.4 -1.5 -0.5 -0.3 -1.0 0.4 0.2 -2.4 -0.1 0.2 -0.6 -0.2 -0.5
Medication: Atorvastatin 0.7 0.8 4.1 -0.5 0.6 2.0 1.2 -0.6 -0.7 -0.5 -0.7 -0.6 0.9 0.7 0.8 0.1 1.2 0.7 -1.9 -0.2 0.0 0.9 0.6 0.1
Illnesses of father: High blood pressure 0.6 0.7 3.1 0.6 0.0 0.6 -0.3 0.6 0.1 -0.7 -1.5 -1.5 -1.8 0.4 -1.0 -0.2 0.1 0.7 -0.9 -0.5 1.2 -0.1 -1.0 -0.7
Alcohol drinker status: Never 1.2 1.5 5.0 0.8 -0.2 -0.1 -0.5 0.6 1.7 1.9 1.8 1.9 2.2 0.4 0.2 1.3 -0.5 1.5 2.0 0.8 1.2 -0.2 0.5 -0.1
Ever smoked 0.7 1.2 4.2 -0.2 1.2 1.9 0.7 -1.1 -1.7 -0.8 -1.4 -1.2 -2.0 0.7 -0.6 -0.5 0.9 -0.3 -2.0 -0.7 -0.2 -0.1 -0.6 -0.1
Basal metabolic rate 0.1 0.6 2.7 -0.5 0.4 1.1 0.5 -0.2 -0.7 0.2 0.9 0.3 -0.3 0.2 1.6 1.0 0.3 -0.8 -1.6 -0.5 -1.3 -0.6 -0.6 0.1
Leg fat percentage (left) 1.9 7.0 27.5 0.9 -1.8 0.9 0.9 -2.2 1.3 -4.8 -4.1 -5.2 -2.9 -3.9 -1.9 -4.0 -0.5 -0.2 -3.7 0.0 0.6 1.4 -2.6 -0.8
Arm fat-free mass (left) 0.3 1.3 4.4 -1.1 1.0 1.9 1.2 -0.7 -1.3 0.9 1.4 1.0 -0.1 0.8 2.1 1.6 1.2 -1.2 -0.9 -0.0 -1.5 -0.2 0.5 1.0
Number of operations (self-reported) 0.7 1.1 4.9 -0.2 2.2 2.1 1.6 -0.7 -0.5 0.1 -0.8 -0.3 -1.3 0.9 0.0 0.8 1.4 0.9 -1.4 -0.3 0.9 0.3 0.8 0.2
Average weekly beer plus cider intake 0.6 0.9 3.2 1.2 -0.4 0.6 -0.2 -0.0 0.7 -0.9 -1.1 -0.5 -1.8 -1.7 -1.3 -0.9 -0.4 0.7 -0.2 0.6 1.8 0.6 -0.8 -0.4
Irritability 0.6 1.0 3.9 1.0 0.6 0.5 0.3 -1.0 1.4 -0.3 -1.3 -1.5 -0.9 -0.5 -1.2 -1.7 0.0 1.2 -2.0 0.0 1.1 0.2 -0.5 -0.2
Risk taking 0.2 0.4 2.2 0.6 0.3 -0.7 -0.5 0.5 -0.4 -0.1 -0.1 0.1 -0.7 -0.1 -0.5 -0.1 -0.5 0.5 0.7 0.9 1.5 -0.6 -0.5 -0.6
Ever had prostate specific antigen (PSA) test 0.6 0.6 4.7 -0.9 -0.5 0.4 0.5 -1.2 -0.2 0.7 1.0 0.0 0.5 -0.0 0.5 0.7 0.1 -0.8 0.2 -1.4 -2.2 0.3 0.8 0.6
Fractured/broken bones in last 5 years 0.6 0.8 3.0 -1.2 0.2 -0.4 0.4 0.2 -1.0 -0.0 -0.3 0.5 -1.4 1.7 1.0 1.3 0.5 -0.8 0.9 -0.7 -1.6 -0.3 -0.3 0.8
Age started oral contraceptive pill 1.0 1.2 6.8 -0.1 -0.8 -0.3 0.2 0.5 1.1 1.4 2.3 0.7 0.2 0.1 0.1 0.3 1.5 0.2 2.6 0.6 -1.0 -0.6 2.0 0.7
Diastolic blood pressure, automated reading 3.1 9.5 20.1 -3.6 3.1 4.5 4.3 -4.2 -2.9 -3.4 -4.3 -2.5 -1.6 0.6 3.0 2.1 2.8 -3.0 -4.2 0.9 -2.1 3.5 0.7 2.8
Ever depressed for a whole week 0.8 1.0 3.9 0.8 -0.9 -1.5 -1.6 1.1 0.9 -0.5 -0.1 -0.2 -0.9 -0.1 -1.0 0.1 -1.4 0.7 0.6 -1.0 0.3 -1.1 -2.0 -1.2
Unable to work because of sickness or disability 0.6 0.8 4.6 0.3 -0.2 -0.3 -0.4 1.6 -1.3 1.7 1.0 0.6 -1.2 0.7 -0.4 0.1 0.2 0.4 0.5 0.1 0.1 -2.1 -0.0 -0.9
Commuting to job workplace: Cycle 1.0 1.3 5.7 -0.1 1.7 1.4 1.4 -1.8 0.5 0.9 0.4 1.5 2.4 0.9 0.5 0.9 0.6 0.5 -0.5 -0.6 0.7 1.5 1.0 0.9
Myopia 0.3 0.5 2.9 -0.5 -0.4 -0.4 0.0 0.4 -0.7 0.4 0.7 1.7 -0.4 0.2 0.9 0.5 -0.7 -1.1 0.8 0.3 -0.8 0.2 0.6 0.5
Vascular/heart problems diagnosed by doctor 1.1 2.9 10.8 1.0 -0.9 -3.3 -2.2 2.0 1.3 2.8 2.8 2.1 1.4 1.1 -1.1 0.3 -1.9 1.1 2.2 -1.3 0.4 -1.2 -0.5 -0.8
Cholesterol lowering medication 0.7 1.0 5.0 -0.6 -0.7 1.0 -0.2 0.8 -2.1 -1.8 -0.4 -0.6 -2.2 0.8 0.4 0.8 0.6 0.0 0.3 -0.2 -0.4 -0.5 -1.5 -0.6
Medication: Omeprazole (e.g. Zanprol) 3.8 4.7 13.1 -2.2 2.3 2.0 1.9 -0.2 -3.6 1.4 1.4 3.2 0.5 2.9 2.9 2.5 2.7 -1.5 0.9 2.1 -0.8 0.7 2.5 2.5
Pain experienced in last month 0.3 0.6 2.0 0.0 -0.9 -1.1 -0.7 -0.0 0.9 0.7 -0.0 -0.2 1.2 -1.2 -0.4 -0.4 -1.4 -0.4 0.2 -1.1 -0.6 0.6 0.8 -0.0
Supplements: Calcium 0.3 0.3 1.5 -0.5 0.7 -0.1 0.2 -0.3 -0.9 -0.4 -0.7 -0.8 -0.6 1.2 -0.4 -0.1 1.1 -0.4 -0.4 0.1 -0.4 0.3 -0.0 0.3
Basal cell carcinoma (self-reported) 2.6 3.1 8.4 1.6 -2.1 -2.5 -2.5 2.9 0.5 1.1 1.4 0.8 -1.0 -1.2 -1.8 -0.7 -2.3 0.8 2.8 -0.5 0.7 -2.6 -1.7 -1.9
Heart attack/myocardial infarction (self-reported) 4.3 5.6 14.0 -2.8 2.4 3.2 3.1 -2.6 -2.5 -1.7 -1.2 -0.1 1.1 1.2 3.1 2.2 3.7 -2.6 -1.9 0.5 -2.6 2.4 2.3 2.6
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 2.5 0.2 -0.8 -1.2 -1.1 0.6 0.3 0.4 1.0 0.3 1.2 0.5 0.1 0.2 -1.6 0.4 -0.3 -1.3 -0.7 -0.8 -0.8 -0.8
Heart disease (siblings) 2.8 3.4 13.5 -1.8 2.5 2.2 2.0 -0.6 -2.7 -1.0 -0.7 2.2 0.0 2.8 2.3 3.7 2.6 -1.1 0.2 -0.9 -0.7 1.4 0.5 1.1
Alcohol drinker status: Previous 0.5 0.6 2.0 0.8 0.6 -0.6 -0.5 1.0 -0.3 -0.7 -0.7 -0.7 -1.4 0.4 -0.7 -0.9 -0.1 0.8 0.2 -0.1 1.2 -1.2 -0.5 -1.1
Pack years of smoking 2.0 2.9 16.7 -2.3 1.7 1.5 1.3 -0.9 -4.1 -0.9 -1.0 1.4 -0.4 1.8 2.5 1.4 1.2 -2.1 -0.7 2.2 -0.8 0.7 0.7 1.6
Impedance of whole body 1.1 5.4 17.4 2.1 -1.2 -1.7 -1.5 0.4 1.6 -3.2 -3.2 -3.5 -1.8 -0.7 -4.2 -2.7 -0.8 2.1 -1.8 -2.2 2.0 -0.2 -3.6 -2.9
Leg fat mass (left) 1.1 4.4 16.9 0.6 -1.1 1.2 0.8 -1.8 0.8 -3.5 -2.9 -4.1 -2.4 -3.1 -1.2 -2.9 -0.3 -0.2 -3.9 -0.5 0.1 0.6 -2.4 -0.9
Arm predicted mass (left) 0.3 1.5 5.6 -1.4 1.0 1.8 1.4 -0.9 -1.3 0.7 1.1 0.8 0.2 0.9 2.4 1.6 1.2 -1.4 -0.9 0.1 -1.7 0.2 0.6 1.3