Best TWAS P=5.22e-09 · Best GWAS P=3.93e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | DCBLD2 | 0.16 | 0.13 | lasso | 3 | 0.14 | 2.4e-11 | 5.8 | -5.6 | 2.0e-08 | -0.99 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Brain Frontal Cortex BA9 | DCBLD2 | 0.32 | 0.22 | lasso | 7 | 0.22 | 1.6e-06 | 4.8 | -5.5 | 3.9e-08 | -0.91 | 0.02 | 0.97 | FALSE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | DCBLD2 | 0.24 | 0.21 | lasso | 4 | 0.19 | 1.4e-07 | 5.4 | -5.4 | 6.1e-08 | -0.98 | 0.02 | 0.98 | FALSE |
| 4 | GTEx | Esophagus Muscularis | DCBLD2 | 0.21 | 0.19 | lasso | 6 | 0.17 | 1.6e-10 | 4.7 | -5.5 | 3.5e-08 | -0.95 | 0.02 | 0.98 | FALSE |
| 5 | GTEx | Pituitary | DCBLD2 | 0.16 | 0.08 | lasso | 8 | 0.08 | 5.1e-03 | 4.7 | -5.3 | 9.1e-08 | -0.96 | 0.02 | 0.92 | FALSE |
| 6 | GTEx | Skin Sun Exposed Lower leg | DCBLD2 | 0.17 | 0.12 | lasso | 7 | 0.15 | 9.2e-13 | -4.6 | -5.5 | 3.8e-08 | -0.81 | 0.13 | 0.87 | FALSE |
| 7 | GTEx | Thyroid | DCBLD2 | 0.14 | 0.12 | lasso | 5 | 0.15 | 1.5e-11 | 5.8 | -5.8 | 5.2e-09 | -0.97 | 0.01 | 0.99 | TRUE |
| 8 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | DCBLD2 | 0.07 | 0.06 | enet | 3 | 0.07 | 7.6e-04 | 5.4 | -5.6 | 2.4e-08 | -0.85 | 0.02 | 0.87 | FALSE |