Best TWAS P=3.63e-11 · Best GWAS P=5.15e-14 conditioned to 0.0403
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | ABCF3 | 0.13 | 0.08 | lasso | 4 | 0.11 | 1.6e-09 | -5.3 | -5.7 | 1.0e-08 | -0.33 | 0.96 | 0.03 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | ABCF3 | 0.07 | 0.00 | blup | 51 | 0.01 | 4.4e-02 | -5.2 | -5.3 | 1.4e-07 | -0.25 | 0.01 | 0.86 | FALSE |
| 3 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ABCF3 | 0.08 | 0.03 | blup | 51 | 0.06 | 6.1e-04 | -3.2 | -5.4 | 7.5e-08 | -0.22 | 0.02 | 0.65 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | PSMD2 | 0.09 | 0.02 | blup | 50 | 0.05 | 1.2e-06 | 7.5 | -6.6 | 3.6e-11 | -0.78 | 0.00 | 0.99 | TRUE |
| 5 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | VWA5B2 | 0.10 | 0.04 | blup | 51 | 0.04 | 1.8e-02 | -5.2 | 6.3 | 3.5e-10 | 0.37 | 0.03 | 0.33 | FALSE |