[Hub]/) : Traits : Impedance of arm (right) : ← →

chr1:77,655,651-79,300,939

Best TWAS P=7.87e-10 · Best GWAS P=2.73e-09 conditioned to 0.318

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes NEXN 0.23 0.10 lasso 3 0.08 1.4e-03 5.6 5.8 7.0e-09 0.73 0.04 0.81 FALSE
2 GTEx Lung GIPC2 0.15 0.09 enet 17 0.12 2.5e-09 5.4 -5.7 1.1e-08 -0.79 0.09 0.91 FALSE
3 GTEx Nerve Tibial DNAJB4 0.08 0.07 lasso 3 0.07 1.3e-05 5.7 5.6 1.9e-08 0.75 0.04 0.96 FALSE
4 GTEx Skin Sun Exposed Lower leg DNAJB4 0.07 0.05 lasso 5 0.05 6.5e-05 5.7 5.2 2.3e-07 0.72 0.03 0.94 FALSE
5 GTEx Spleen GIPC2 0.43 0.07 enet 19 0.22 2.9e-06 5.6 -6.0 2.6e-09 -0.92 0.02 0.97 FALSE
6 METSIM Adipose DNAJB4 0.04 0.04 lasso 4 0.03 2.1e-05 4.9 5.5 3.1e-08 0.60 0.16 0.78 FALSE
7 ROSMAP Brain Pre-frontal Cortex DNAJB4 0.08 0.09 lasso 2 0.09 1.3e-11 5.1 5.2 2.2e-07 0.76 0.29 0.71 FALSE
8 YFS Blood NEXN 0.02 0.01 blup 367 0.02 1.2e-06 5.3 -5.4 8.4e-08 -0.67 0.06 0.90 FALSE
9 The Cancer Genome Atlas Bladder Urothelial Carcinoma DNAJB4 0.05 0.03 lasso 3 0.02 3.3e-03 5.0 5.4 6.2e-08 0.76 0.00 0.98 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma GIPC2 0.04 0.01 blup 65 0.00 2.5e-01 5.1 -6.2 7.9e-10 -0.89 0.02 0.73 TRUE
11 The Cancer Genome Atlas Brain Lower Grade Glioma GIPC2 0.02 0.02 lasso 3 0.02 1.0e-03 5.9 -5.8 5.8e-09 -0.99 0.01 0.97 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma DNAJB4 0.04 0.04 lasso 2 0.04 1.2e-05 -5.2 5.2 2.0e-07 0.33 0.01 0.98 FALSE