Best TWAS P=1.77e-07 · Best GWAS P=8.83e-07 conditioned to 0.741
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Gastroesophageal Junction | MED24 | 0.26 | 0.16 | lasso | 11 | 0.20 | 1.1e-07 | 4.1 | -5.2 | 1.8e-07 | -0.92 | 0.01 | 0.95 | TRUE |
2 | GTEx | Spleen | MED24 | 0.35 | 0.21 | lasso | 6 | 0.24 | 6.5e-07 | 4.1 | -5.1 | 2.9e-07 | -0.89 | 0.02 | 0.94 | FALSE |