Best TWAS P=1.46e-09 · Best GWAS P=1.43e-18 conditioned to 1e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PEPD | 0.32 | 0.27 | enet | 22 | 0.38 | 1.2e-49 | 4.5 | 5.1 | 2.9e-07 | -0.44 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | CEBPG | 0.16 | 0.08 | enet | 11 | 0.14 | 6.1e-12 | -3.7 | 5.2 | 1.6e-07 | -0.46 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PEPD | 0.08 | 0.04 | lasso | 8 | 0.03 | 2.8e-04 | 6.2 | 5.8 | 6.2e-09 | -0.24 | 0.29 | 0.02 | TRUE |
| 4 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | KCTD15 | 0.25 | 0.05 | lasso | 4 | 0.04 | 3.3e-02 | 6.2 | 6.0 | 1.5e-09 | 0.02 | 0.00 | 0.93 | TRUE |