TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of arm (left)
:
←
→
chr19:33,164,759-34,691,449
Best TWAS P=1.46e-09 · Best GWAS P=1.43e-18 conditioned to 1e-14
33.2M
33.4M
33.6M
33.8M
34M
34.2M
34.4M
34.6M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Skin Cutaneous Melanoma
KCTD15
0.25
0.05
lasso
4
0.04
3.3e-02
6.2
6.0
1.5e-09
0.02
0.00
0.93
TRUE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
PEPD
0.08
0.04
lasso
8
0.03
2.8e-04
6.2
5.8
6.2e-09
-0.24
0.29
0.02
TRUE
2
GTEx
Skin Sun Exposed Lower leg
CEBPG
0.16
0.08
enet
11
0.14
6.1e-12
-3.7
5.2
1.6e-07
-0.46
1.00
0.00
FALSE
1
CommonMind
Brain Pre-frontal Cortex
PEPD
0.32
0.27
enet
22
0.38
1.2e-49
4.5
5.1
2.9e-07
-0.44
1.00
0.00
FALSE