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chr11:130,038,487-131,476,599

Best TWAS P=7.16e-09 · Best GWAS P=2.06e-08 conditioned to 0.176

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Brain Hypothalamus	SNX19	0.32	0.04	lasso	5	0.13	7.4e-04	4.9	-5.8	7.2e-09	0.84	0.06	0.89	TRUE
8	GTEx	Esophagus Muscularis	SNX19	0.31	0.18	enet	23	0.25	1.2e-15	4.6	-5.7	1.3e-08	0.85	0.05	0.95	FALSE
11	GTEx	Pancreas	RP11-890B15.3	0.16	0.02	lasso	2	0.01	1.9e-01	-5.6	-5.5	2.9e-08	0.95	0.03	0.91	FALSE
13	GTEx	Testis	SNX19	0.59	0.25	enet	24	0.38	7.1e-18	-5.6	-5.5	2.9e-08	0.86	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SNX19	0.06	0.04	blup	100	0.06	1.3e-03	4.1	-5.5	3.0e-08	0.74	0.05	0.49	FALSE
4	GTEx	Brain Caudate basal ganglia	SNX19	0.33	0.12	lasso	5	0.12	2.8e-04	4.8	-5.5	3.8e-08	0.92	0.05	0.90	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	SNX19	0.41	0.49	lasso	6	0.51	2.7e-75	4.8	-5.5	4.6e-08	0.83	0.35	0.65	FALSE
12	GTEx	Stomach	SNX19	0.39	0.29	lasso	13	0.27	2.0e-13	4.8	-5.5	4.7e-08	0.86	0.23	0.76	FALSE
1	GTEx	Adipose Subcutaneous	SNX19	0.21	0.15	enet	24	0.16	2.3e-13	4.8	-5.4	5.4e-08	0.81	0.20	0.80	FALSE
10	GTEx	Heart Left Ventricle	SNX19	0.21	0.06	lasso	4	0.05	9.7e-04	4.8	-5.4	5.7e-08	0.91	0.05	0.93	FALSE
2	GTEx	Adipose Visceral Omentum	SNX19	0.22	0.10	lasso	7	0.10	8.0e-06	4.8	-5.4	7.4e-08	0.87	0.09	0.90	FALSE
6	GTEx	Brain Frontal Cortex BA9	SNX19	0.41	0.20	lasso	7	0.37	7.1e-11	-5.2	-5.3	9.1e-08	0.84	0.04	0.94	FALSE
15	The Cancer Genome Atlas	Esophageal Carcinoma	SNX19	0.15	0.08	lasso	6	0.12	1.4e-04	4.8	-5.3	1.2e-07	0.74	0.14	0.67	FALSE
3	GTEx	Adrenal Gland	SNX19	0.24	0.16	lasso	4	0.06	3.2e-03	4.6	-5.2	2.0e-07	0.88	0.10	0.89	FALSE
9	GTEx	Heart Atrial Appendage	SNX19	0.50	0.20	enet	32	0.32	4.9e-15	-5.3	-5.2	2.1e-07	0.72	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SNX19	0.11	0.19	enet	15	0.24	3.2e-26	4.8	-5.2	2.4e-07	0.70	0.32	0.67	FALSE
5	GTEx	Brain Cortex	SNX19	0.36	0.12	lasso	7	0.16	3.3e-05	4.6	-5.1	3.0e-07	0.92	0.04	0.94	FALSE