Best TWAS P=1.87e-13 · Best GWAS P=8.85e-14 conditioned to 0.0323
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | PEPD | 0.37 | 0.32 | enet | 20 | 0.39 | 9.5e-28 | 4.8 | 6.1 | 7.8e-10 | 0.90 | 0.02 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | PEPD | 0.06 | 0.01 | blup | 114 | 0.04 | 2.6e-04 | 7.5 | 6.5 | 9.4e-11 | 0.86 | 0.01 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | PEPD | 0.13 | 0.06 | blup | 113 | 0.10 | 1.2e-06 | 4.2 | 7.4 | 1.9e-13 | 0.87 | 0.02 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | PEPD | 0.16 | 0.07 | lasso | 3 | 0.05 | 3.1e-03 | 7.4 | 7.1 | 1.0e-12 | 0.98 | 0.01 | 0.96 | FALSE |