TWAS
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Traits
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Traits
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Leg fat percentage (right)
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chr19:33,182,320-34,691,449
Best TWAS P=1.87e-13 · Best GWAS P=8.85e-14 conditioned to 0.0323
33.2M
33.4M
33.6M
33.8M
34M
34.2M
34.4M
34.6M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Colon Adenocarcinoma
PEPD
0.13
0.06
blup
113
0.10
1.2e-06
4.2
7.4
1.9e-13
0.87
0.02
0.98
TRUE
4
The Cancer Genome Atlas
Liver Hepatocellular Carcinoma
PEPD
0.16
0.07
lasso
3
0.05
3.1e-03
7.4
7.1
1.0e-12
0.98
0.01
0.96
FALSE
2
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
PEPD
0.06
0.01
blup
114
0.04
2.6e-04
7.5
6.5
9.4e-11
0.86
0.01
0.97
FALSE
1
GTEx
Esophagus Mucosa
PEPD
0.37
0.32
enet
20
0.39
9.5e-28
4.8
6.1
7.8e-10
0.90
0.02
0.98
FALSE