Best TWAS P=2.35e-10 · Best GWAS P=1.71e-11 conditioned to 7.82e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CENPW | 0.04 | 0.06 | lasso | 10 | 0.06 | 2.4e-07 | -6.2 | 6.3 | 2.4e-10 | 0.54 | 0.10 | 0.90 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CENPW | 0.04 | 0.05 | lasso | 5 | 0.05 | 2.6e-06 | -5.9 | 5.4 | 7.2e-08 | 0.44 | 0.02 | 0.98 | FALSE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CENPW | 0.04 | 0.06 | blup | 35 | 0.05 | 9.2e-07 | -6.0 | 5.4 | 6.9e-08 | 0.41 | 0.03 | 0.97 | FALSE |