[Hub]/) : Traits : Leg fat mass (right) : →

chr1:903,104-3,212,946

Best TWAS P=1.09e-10 · Best GWAS P=6.92e-10 conditioned to 0.0294

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	RP1-283E3.4	0.65	0.14	lasso	9	0.33	5.1e-28	-3.4	-5.8	8.1e-09	0.00	0.68	0.09	FALSE
2	GTEx	Adipose Visceral Omentum	RP1-283E3.4	0.26	0.05	enet	25	0.16	1.5e-08	-3.4	-5.5	2.8e-08	-0.02	0.12	0.06	FALSE
3	GTEx	Artery Aorta	RP1-283E3.4	0.60	0.12	lasso	9	0.27	3.2e-15	-3.4	-5.4	8.6e-08	-0.01	0.37	0.12	FALSE
4	GTEx	Artery Tibial	RP1-283E3.4	0.66	0.09	lasso	6	0.38	4.9e-31	-3.4	-5.4	8.5e-08	0.01	0.69	0.07	FALSE
5	GTEx	Artery Tibial	RP11-345P4.10	0.61	0.10	lasso	10	0.36	3.1e-29	-3.3	5.2	1.5e-07	0.01	0.70	0.06	FALSE
6	GTEx	Cells Transformed fibroblasts	RP1-283E3.4	0.59	0.13	lasso	8	0.29	3.0e-22	2.6	-5.8	6.0e-09	0.01	0.74	0.01	FALSE
7	GTEx	Esophagus Mucosa	RP1-283E3.4	0.53	0.12	enet	20	0.22	4.1e-15	-3.4	-6.0	1.6e-09	0.02	0.68	0.09	FALSE
8	GTEx	Esophagus Muscularis	RP1-283E3.4	0.46	0.14	enet	23	0.24	1.6e-14	-3.4	-6.5	1.1e-10	0.01	0.65	0.09	TRUE
9	GTEx	Esophagus Muscularis	RP3-395M20.12	0.08	0.06	enet	6	0.06	2.3e-04	4.3	-6.0	2.7e-09	0.78	0.01	0.98	TRUE
10	GTEx	Heart Atrial Appendage	RP11-345P4.10	0.36	0.11	enet	15	0.16	1.1e-07	-3.3	5.2	2.5e-07	-0.01	0.07	0.05	FALSE
11	GTEx	Lung	RP1-283E3.4	0.58	0.07	lasso	7	0.34	8.8e-27	-3.4	-5.3	1.0e-07	0.02	0.70	0.05	FALSE
12	GTEx	Muscle Skeletal	TMEM52	0.11	0.08	lasso	6	0.10	7.2e-10	-4.6	5.2	2.4e-07	-0.02	0.04	0.94	TRUE
13	GTEx	Muscle Skeletal	SLC35E2B	0.35	0.06	lasso	4	0.19	3.2e-18	-3.3	5.8	7.9e-09	0.01	0.69	0.06	FALSE
14	GTEx	Muscle Skeletal	RP1-283E3.4	0.51	0.12	lasso	6	0.29	2.4e-28	-3.4	-5.4	7.4e-08	0.01	0.68	0.09	FALSE
15	GTEx	Muscle Skeletal	RP11-345P4.10	0.54	0.06	lasso	7	0.29	4.7e-29	-3.3	5.3	1.1e-07	0.00	0.72	0.04	FALSE
16	GTEx	Pancreas	TNFRSF14	0.13	0.04	enet	8	0.04	1.0e-02	4.3	5.2	2.0e-07	-0.63	0.32	0.48	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	RP1-283E3.4	0.48	0.12	lasso	5	0.31	1.1e-17	-3.4	-5.9	3.4e-09	0.01	0.34	0.11	FALSE
18	GTEx	Spleen	RP3-395M20.9	0.42	0.14	lasso	3	0.15	1.1e-04	-5.5	-5.2	1.6e-07	0.59	0.04	0.70	FALSE
19	GTEx	Thyroid	RP1-283E3.4	0.59	0.04	lasso	10	0.22	3.8e-17	-3.4	-6.2	6.0e-10	0.00	0.52	0.08	FALSE
20	METSIM	Adipose	TNFRSF14	0.07	0.05	blup	373	0.05	1.9e-07	4.6	5.3	1.0e-07	-0.63	0.66	0.33	FALSE