TWAS hub - SLC35E2B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1580	0.0540	5.1e-03	0.009	0.023	0.023	0.032	0.009	2.5e-02	6.7e-04	6.4e-04	7.0e-05	2.3e-02
2	GTEx	Adipose Subcutaneous	0.4750	0.0620	3.0e-11	0.165	NA	0.317	NA	0.318	1.8e-13	NA	1.7e-26	NA	1.6e-26
3	GTEx	Artery Aorta	0.5060	0.0850	1.2e-07	0.119	NA	0.257	NA	0.251	4.5e-07	NA	1.9e-14	NA	4.4e-14
4	GTEx	Artery Tibial	0.4406	0.0781	2.7e-07	0.139	NA	0.241	NA	0.213	5.3e-11	NA	7.6e-19	NA	1.2e-16
5	GTEx	Brain Frontal Cortex BA9	0.3699	0.1152	4.5e-03	0.068	NA	0.171	NA	0.161	7.1e-03	NA	2.7e-05	NA	4.7e-05
6	GTEx	Breast Mammary Tissue (Male)	0.0273	0.0505	3.3e-01	0.000	NA	-0.011	NA	-0.009	3.2e-01	NA	6.8e-01	NA	5.9e-01
7	GTEx	Breast Mammary Tissue (Female)	0.1099	0.0859	1.1e-01	0.012	NA	0.095	NA	0.003	1.4e-01	NA	9.1e-04	NA	2.6e-01
8	GTEx	Cells Transformed fibroblasts	0.4740	0.0740	9.7e-10	0.171	NA	0.216	NA	0.230	7.9e-13	NA	3.5e-16	NA	3.3e-17
9	GTEx	Esophagus Mucosa	0.3280	0.0800	2.7e-04	0.171	NA	0.223	NA	0.200	1.6e-11	NA	5.6e-15	NA	2.0e-13
10	GTEx	Esophagus Muscularis	0.4120	0.0830	6.2e-06	0.195	NA	0.300	NA	0.291	5.6e-12	NA	1.2e-18	NA	5.0e-18
11	GTEx	Heart Atrial Appendage	0.2210	0.0990	9.8e-03	0.009	NA	0.008	NA	0.025	1.2e-01	NA	1.3e-01	NA	2.6e-02
12	GTEx	Lung	0.3056	0.0727	3.7e-05	0.154	NA	0.146	NA	0.155	7.1e-12	NA	2.7e-11	NA	6.5e-12
13	GTEx	Muscle Skeletal	0.3535	0.0745	2.0e-04	0.057	NA	0.182	NA	0.189	2.6e-06	NA	1.5e-17	NA	3.2e-18
14	GTEx	Nerve Tibial	0.1890	0.0947	9.0e-03	0.091	NA	0.078	NA	0.081	5.5e-07	NA	3.5e-06	NA	2.5e-06
15	GTEx	Skin Sun Exposed Lower leg	0.4290	0.0680	5.4e-08	0.070	NA	0.262	NA	0.246	1.9e-06	NA	9.4e-22	NA	2.5e-20
16	GTEx	Thyroid	0.4960	0.0670	5.1e-11	0.176	NA	0.237	NA	0.241	1.9e-13	NA	4.1e-18	NA	2.1e-18
17	GTEx	Whole Blood	0.0800	0.0450	9.4e-03	0.039	NA	0.055	NA	0.043	1.6e-04	NA	8.2e-06	NA	7.6e-05
18	METSIM	Adipose	0.2679	0.0537	5.9e-12	0.032	0.093	0.137	0.109	0.129	1.2e-05	8.2e-14	7.0e-20	5.4e-16	1.0e-18
19	ROSMAP	Brain Pre-frontal Cortex	0.0786	0.0262	4.6e-05	0.034	0.043	0.060	0.050	0.033	3.0e-05	2.7e-06	3.0e-08	5.2e-07	3.9e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	7	8	9	10	11	12	13	14	15	16	17	18	19
BMI	6.4	37.0	80.3	3.8	7.1	5.5	6.8	4.0	3.0	7.6	6.8	7.0	7.8	6.5	9.0	8.3	6.5	7.1	4.7	3.2	2.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.3	9.1	18.7	-4.3	-3.4	-1.7	-3.5	-3.2	-3.0	-3.1	-3.5	-3.1	-1.5	-2.9	-4.2	-3.6	-3.1	-3.1	-2.6	-2.4	-2.3
Medication: Blood pressure	4.2	8.1	18.7	1.6	3.9	0.3	2.9	2.7	0.5	3.6	3.1	3.8	3.2	3.2	4.1	4.3	3.2	3.3	2.4	0.6	-0.1
Hand grip strength (left)	3.8	10.0	20.2	3.8	3.6	1.9	2.6	2.7	4.5	3.1	3.5	3.3	2.4	2.9	3.0	2.5	3.5	3.7	3.3	3.9	3.1
Supplements: Fish oil (including cod liver oil)	3.8	4.9	8.9	-0.5	-2.2	-2.4	-2.5	-2.8	-2.1	-3.0	-2.3	-3.0	-2.1	-2.1	-1.7	-2.1	-2.6	-2.3	-2.6	-1.8	1.6
Leg fat mass (left)	3.8	14.8	37.1	3.5	4.9	2.8	4.3	2.8	1.8	4.7	4.4	4.1	4.0	3.2	6.1	4.6	4.5	4.5	2.9	3.4	2.1
Leg fat mass (right)	3.7	14.4	33.3	3.5	4.8	3.1	4.2	2.9	1.9	4.6	4.4	3.9	4.0	3.2	5.8	4.3	4.5	4.4	2.9	3.5	2.0
Illnesses of father: High blood pressure	3.6	4.5	7.7	2.5	2.5	0.3	2.3	2.8	1.6	2.5	2.4	2.5	0.7	2.4	2.5	2.5	2.3	2.1	2.7	1.5	1.0
Medication: Metformin	3.5	4.9	11.7	1.7	2.5	1.2	2.7	2.5	1.9	3.0	2.3	2.7	1.7	2.1	3.4	3.1	2.0	2.5	1.8	1.1	-0.4
Type 2 Diabetes (T2D) (2018)	3.4	6.4	14.4	1.9	2.9	1.1	2.9	2.7	1.6	3.5	2.9	2.8	2.3	3.1	3.5	3.8	2.3	2.7	2.2	0.9	0.7
Reason for reducing amount of alcohol drunk: Health precaution	3.4	4.0	6.9	-0.1	2.4	1.9	2.6	1.1	1.6	2.2	2.2	2.4	2.0	2.5	2.1	2.4	2.5	2.6	1.9	1.6	0.7
Leg fat percentage (left)	3.3	11.9	37.7	3.0	4.6	2.5	3.8	2.3	0.6	4.2	4.1	3.6	3.4	2.9	6.1	4.5	4.0	3.7	2.5	2.5	0.8
Waist circumference	3.2	11.6	30.1	3.5	4.3	1.9	3.5	2.3	1.5	4.2	4.0	3.7	3.5	2.8	5.5	4.0	4.2	4.0	2.5	3.0	1.9
Leg fat percentage (right)	3.2	11.5	30.8	2.9	4.5	3.1	3.8	2.3	1.0	4.2	4.1	3.3	3.5	2.9	5.5	4.2	3.9	3.7	2.6	2.9	0.9
Whole body fat mass	3.2	13.5	32.5	2.7	4.6	3.2	4.1	2.7	1.8	4.7	4.1	4.1	4.0	3.2	5.7	4.4	4.3	4.4	2.9	3.0	1.7
Body mass index (BMI)	3.0	12.8	42.0	3.2	4.6	2.4	3.9	2.2	0.7	4.3	4.0	4.1	3.6	2.7	6.5	4.6	4.4	4.1	2.1	2.6	2.1
Leg pain on walking	3.0	3.8	10.4	3.2	2.5	1.2	1.6	1.8	0.7	2.2	2.5	1.8	0.8	2.0	2.0	1.8	2.3	2.1	2.1	2.5	0.6
Weight	2.9	14.5	26.5	3.8	4.4	2.3	4.0	3.3	2.9	4.8	4.0	4.0	4.0	3.2	5.1	4.1	4.3	4.8	3.0	3.7	3.3
Arm fat mass (right)	2.9	11.9	32.2	2.9	4.2	2.7	3.9	2.3	1.1	4.3	3.7	3.9	3.9	2.8	5.7	4.3	4.1	4.1	2.3	2.7	2.3
Tense / ‘highly strung’	2.9	4.8	12.3	1.6	2.5	1.1	2.3	3.5	1.7	2.8	2.8	2.2	1.5	2.6	1.5	2.1	2.2	2.4	3.0	2.2	0.6
Trunk fat mass	2.8	12.1	26.0	2.4	4.3	3.2	3.8	2.7	1.9	4.5	3.9	3.8	3.7	3.1	5.1	4.0	3.9	4.2	3.0	3.0	1.4
Arm fat mass (left)	2.8	11.6	32.2	2.9	4.2	2.4	3.7	2.5	1.2	4.4	3.7	3.9	3.7	2.8	5.7	4.3	4.0	4.0	2.3	2.6	1.9
Noisy workplace	2.7	3.4	7.4	-0.7	-1.6	-1.7	-1.5	-2.0	-2.7	-2.1	-2.0	-1.8	-2.7	-2.4	-0.6	-1.4	-1.4	-2.0	-2.6	-1.6	-1.5
Serious illness, injury or assault of a close relative in last 2 years	2.7	3.1	7.5	0.2	1.7	0.0	1.5	2.3	1.6	2.6	1.8	2.1	2.2	2.4	0.9	1.8	1.5	2.2	2.7	1.6	0.6
Loud music exposure frequency	2.7	3.0	6.8	0.1	2.1	2.6	2.5	1.5	0.9	1.8	2.0	1.8	1.9	1.9	2.1	2.2	1.6	2.1	1.3	0.6	-0.5
Crohns Disease (2017)	2.6	5.8	16.6	2.5	0.0	3.7	3.8	4.1	2.5	3.7	0.0	3.4	0.0	0.0	0.0	0.0	2.8	0.0	3.7	2.3	0.2
Body fat percentage	2.6	10.3	30.7	1.9	4.2	3.3	3.6	1.8	0.7	4.1	3.8	3.6	3.2	2.7	5.5	4.1	3.7	3.5	2.5	2.4	0.4
Arm predicted mass (right)	2.6	13.5	22.1	4.3	3.7	1.7	3.8	3.7	4.3	4.4	3.7	3.5	3.6	3.2	3.9	3.3	3.7	4.7	3.1	3.7	4.6
Long-standing illness, disability or infirmity	2.6	3.9	10.2	1.3	2.5	0.9	2.4	2.2	0.6	2.4	2.0	2.3	2.0	1.5	3.2	2.6	2.5	2.2	1.4	1.6	0.7
Arm fat-free mass (left)	2.6	13.4	22.9	4.3	3.7	1.4	3.7	3.5	4.2	4.3	3.5	3.6	3.6	3.1	4.0	3.3	3.7	4.7	3.0	3.8	4.8
Cholesterol lowering medication	2.6	3.8	7.6	1.3	2.8	2.1	2.3	1.5	1.0	2.1	2.5	2.4	1.1	1.6	2.7	2.0	2.7	2.2	1.9	1.8	0.5
Arm fat-free mass (right)	2.4	12.2	22.8	4.2	3.4	1.4	3.5	3.5	4.3	4.1	3.3	3.4	3.4	2.8	3.7	3.0	3.5	4.5	2.9	3.5	4.8
Arm fat percentage (left)	2.4	9.7	34.1	1.9	4.1	2.8	3.5	1.6	-0.1	3.9	3.5	3.6	3.0	2.4	5.8	4.2	3.8	3.3	2.0	1.9	0.8
Leg fat-free mass (left)	2.3	12.1	20.9	3.3	3.5	2.1	3.8	3.3	3.6	4.2	3.2	3.6	3.7	2.7	4.0	3.2	3.8	4.6	2.8	3.5	4.3
Hand grip strength (right)	2.3	6.4	11.6	2.7	3.0	0.9	1.9	2.7	3.4	2.9	2.7	2.9	1.5	2.0	3.0	2.2	2.9	3.2	2.4	3.2	1.8
Leg predicted mass (left)	2.3	12.2	20.9	3.4	3.5	2.1	3.8	3.3	3.6	4.3	3.2	3.6	3.8	2.8	4.0	3.2	3.8	4.6	2.8	3.5	4.3
Arm fat percentage (right)	2.3	9.0	30.7	1.9	3.9	2.7	3.4	1.4	-0.0	3.7	3.3	3.4	3.2	2.3	5.5	4.0	3.6	3.3	1.8	1.9	1.0
Medication: Aspirin	2.3	3.1	5.8	1.5	2.1	1.2	2.0	1.0	1.7	2.0	2.1	1.9	1.5	2.1	2.0	2.1	1.7	2.0	2.4	1.5	-0.0
Basal metabolic rate	2.3	12.8	21.8	4.0	3.6	1.6	3.7	3.5	4.0	4.3	3.4	3.5	3.9	3.0	3.9	3.3	3.7	4.7	2.8	3.6	4.6
Arm predicted mass (left)	2.3	11.7	20.2	4.3	3.4	1.1	3.4	3.1	4.0	4.0	3.3	3.4	3.5	2.9	3.7	3.0	3.5	4.5	2.8	3.5	4.5
Hip circumference	2.2	9.6	19.3	2.1	3.7	2.3	3.2	2.4	2.4	4.0	3.3	3.5	3.5	2.9	4.4	3.6	3.4	4.0	2.1	2.6	2.7
Qualifications: College or University degree	2.2	7.1	12.9	-2.1	-2.8	-1.8	-2.7	-3.1	-2.8	-3.4	-2.7	-3.4	-3.0	-2.0	-3.0	-2.4	-2.6	-2.9	-3.6	-2.3	1.5
Eye problems/disorders: None of the above	2.2	2.6	5.1	1.0	1.8	2.3	1.4	0.8	1.6	1.7	2.1	1.6	1.7	2.2	1.1	1.7	1.4	2.2	1.8	1.3	0.7
Diabetes diagnosed by doctor	2.2	3.7	8.9	1.9	2.1	0.9	2.4	1.7	1.9	2.7	2.1	2.1	1.1	1.6	3.0	2.3	1.7	2.0	1.9	1.5	1.1
Trunk fat percentage	2.1	8.3	22.8	1.4	3.8	3.1	3.2	1.7	0.7	3.8	3.3	3.2	2.9	2.4	4.8	3.6	3.3	3.3	2.3	2.2	0.2
Diabetes (self-reported)	2.1	3.2	6.9	2.0	1.9	0.6	2.2	1.8	2.0	2.6	1.9	1.9	1.2	1.7	2.6	2.0	1.2	1.8	2.1	1.3	0.9
Qualifications: NVQ or HND or HNC or equivalent	2.1	2.5	8.3	-0.3	1.6	1.1	1.6	0.3	-0.8	1.8	1.3	1.9	2.7	1.7	2.5	2.9	1.5	1.7	0.6	-0.6	0.5
Whole body fat-free mass	2.1	12.0	24.4	3.9	3.2	1.4	3.5	3.4	4.3	4.1	3.1	3.3	3.8	2.8	3.4	3.0	3.5	4.6	2.7	3.5	4.9
Pain type(s) experienced in last month: Hip pain	2.1	2.6	6.2	1.5	1.5	1.3	2.0	2.5	1.3	2.1	1.5	1.6	2.3	1.2	2.4	1.9	1.2	1.4	1.5	0.9	0.2
Medication for hormone replacement therapy	2.0	2.2	8.4	0.4	-1.8	0.5	-0.9	-0.5	-0.9	-2.2	-1.2	-2.9	-1.3	-1.3	-2.1	-1.8	-1.9	-1.9	-1.4	-1.1	-0.4
Birth weight of first child	2.0	3.6	6.3	-1.6	-2.0	-0.5	-1.9	-2.0	-2.5	-2.4	-2.1	-2.0	-0.5	-1.6	-2.5	-1.9	-1.3	-1.8	-2.5	-2.1	2.3
Whole body water mass	2.0	11.5	23.8	3.9	3.1	1.3	3.5	3.4	4.2	4.0	3.0	3.3	3.7	2.8	3.3	2.9	3.4	4.5	2.7	3.4	4.9
Pulse wave reflection index	1.9	2.4	5.3	-0.3	-1.8	-1.4	-1.3	-2.3	-1.7	-2.1	-1.8	-1.5	-1.4	-2.2	-0.9	-1.7	-1.4	-1.6	-2.1	-1.1	0.0
Glaucoma (self-reported)	1.9	2.2	5.8	-0.8	-1.2	-1.8	-1.9	-0.8	-2.4	-1.5	-1.8	-0.6	-1.4	-1.7	-0.6	-0.9	-0.9	-1.9	-1.8	-1.6	-2.2
High blood pressure (siblings)	1.9	2.7	8.5	1.4	2.5	-0.0	1.8	-0.1	-0.1	1.7	2.0	2.0	0.4	1.6	2.9	2.2	2.3	1.7	1.3	1.9	0.2
Migraine (self-reported)	1.9	2.4	6.7	-0.5	-2.0	-0.5	-0.9	-1.0	-0.7	-2.3	-1.4	-2.6	-1.3	-1.7	-2.0	-1.9	-2.0	-1.9	-2.1	-0.8	-0.4
Illnesses of father: None of the above (group 1)	1.9	2.4	5.4	-2.1	-2.0	-0.3	-1.8	-0.3	-0.2	-1.6	-2.1	-1.6	-1.2	-2.1	-2.3	-2.3	-1.7	-1.4	-1.6	0.1	-0.3
Mother’s age at death	1.9	2.4	6.0	-0.5	-2.1	-1.5	-2.4	-1.7	-1.5	-1.6	-1.8	-1.6	-0.3	-0.7	-2.4	-1.2	-2.1	-1.6	-1.5	-1.7	-0.3
Fluid intelligence score	1.8	3.8	10.3	-1.4	-2.2	-1.2	-2.6	-1.7	-0.9	-2.2	-1.7	-2.5	-2.8	-1.5	-3.2	-2.8	-2.0	-2.2	-1.2	-0.8	0.4
Trunk fat-free mass	1.8	10.2	24.7	4.0	2.7	0.9	3.0	3.4	4.5	3.6	2.7	2.8	3.6	2.7	2.5	2.4	3.0	4.2	2.5	3.4	5.0
Trunk predicted mass	1.8	10.1	24.2	4.0	2.7	0.9	3.0	3.4	4.5	3.6	2.7	2.8	3.6	2.7	2.5	2.5	3.0	4.2	2.5	3.4	4.9
Health satisfaction	1.8	2.4	10.7	2.7	2.5	0.5	2.0	0.6	-0.3	0.8	2.1	0.9	0.1	0.6	3.3	1.4	2.0	0.9	0.6	1.8	-0.1
Emphysema/chronic bronchitis	1.8	2.1	5.2	1.5	1.6	0.4	1.2	2.3	0.7	1.6	1.5	1.1	1.8	2.1	1.1	1.8	1.2	1.3	2.2	0.6	0.7
Leg fat-free mass (right)	1.8	9.6	17.5	3.4	3.0	1.1	3.2	3.0	3.1	3.8	2.7	3.3	3.3	2.3	3.8	2.9	3.4	4.1	2.3	3.0	4.2
Medication: Simvastatin	1.7	2.5	4.9	0.7	2.0	1.5	1.4	1.3	0.5	1.8	1.9	1.9	1.5	2.2	1.9	2.2	1.9	1.6	1.8	0.5	1.1
Leg predicted mass (right)	1.7	9.0	17.3	3.2	2.9	1.1	3.1	2.9	3.0	3.7	2.6	3.2	3.2	2.2	3.6	2.8	3.2	4.0	2.2	2.9	4.2
Hearing aid user	1.7	1.9	6.4	-2.5	-1.2	-1.3	-1.4	-2.5	-1.8	-1.1	-1.3	-0.6	-0.7	-1.0	-1.2	-0.7	-1.5	-0.8	-1.5	-0.8	-1.7
Prostate Cancer	1.6	2.2	5.6	-0.5	1.7	1.0	1.6	0.8	2.4	2.0	1.6	1.5	0.3	1.8	1.5	1.5	1.2	1.7	2.3	1.6	-0.1
Serious illness, injury or assault to yourself	1.6	1.9	3.9	-1.6	-1.7	-1.0	-0.6	-1.0	-0.8	-1.2	-1.6	-1.9	-0.6	-1.5	-0.3	-0.8	-1.8	-2.0	-1.5	-1.9	-2.0
Past tobacco smoking	1.6	3.0	5.1	-0.4	-2.2	-1.0	-1.9	-2.0	-1.4	-2.3	-2.0	-2.0	-1.4	-2.0	-1.9	-2.1	-2.1	-2.3	-1.9	-1.4	0.0
Illnesses of siblings	1.6	2.3	5.3	-1.4	-2.2	0.2	-1.5	-0.7	0.5	-1.7	-1.8	-1.7	-1.3	-1.7	-2.2	-2.3	-1.9	-1.7	-0.9	-1.7	0.4
Medication: Paracetamol	1.6	2.6	9.5	3.1	1.4	1.2	1.8	1.6	2.1	1.7	1.8	0.8	2.2	1.5	1.7	1.4	0.8	1.5	1.8	1.5	-0.4
Eye problems/disorders: Glaucoma	1.6	1.8	5.2	-0.7	-1.0	-2.2	-1.6	-0.9	-2.2	-1.0	-1.5	-0.0	-0.8	-1.5	0.1	-0.4	-0.7	-1.6	-1.5	-1.9	-2.3
Vascular/heart problems diagnosed by doctor	1.6	4.4	11.0	-1.1	-2.9	-0.5	-2.3	-2.1	-0.5	-2.5	-2.3	-2.5	-2.0	-2.6	-3.0	-3.3	-2.4	-2.2	-2.1	-0.1	-0.0
Neuroticism (2016)	1.5	2.1	8.5	-0.2	-1.4	-1.5	-1.6	-0.1	0.3	-1.7	-1.3	-1.5	-2.9	-1.8	-2.2	-2.5	-0.9	-1.5	-0.9	0.4	-0.2
Ever had hysterectomy (womb removed)	1.5	1.7	4.8	-1.0	-1.2	-0.5	-1.5	-2.2	-2.0	-1.6	-1.5	-1.3	-1.1	-1.3	-1.3	-1.0	-1.2	-1.2	-2.1	-0.3	-0.1
Diabetes (mother)	1.5	1.9	5.1	0.3	1.8	1.2	1.5	1.2	-0.7	1.6	1.7	1.7	2.3	1.5	1.4	1.6	1.6	1.4	1.1	0.8	-0.5
Illnesses of mother	1.5	1.9	5.7	-1.9	-1.9	0.1	-1.5	-1.3	0.5	-1.6	-1.7	-1.2	-0.9	-1.3	-2.4	-2.1	-1.8	-0.9	-1.2	-0.1	0.1
Medication for pain relief, constipation, heartburn	1.5	2.5	6.6	-2.6	-1.6	-1.0	-1.4	-2.1	-1.5	-1.8	-1.9	-1.0	-2.0	-1.8	-1.4	-1.6	-0.8	-1.3	-2.0	-1.4	1.2
Medication: Aspirin	1.5	1.9	4.0	1.1	1.8	1.2	1.5	0.5	1.1	1.5	1.8	1.5	1.1	1.7	1.6	1.6	1.5	1.5	2.0	1.2	-0.1
Commuting to job workplace: Cycle	1.5	1.8	3.4	-1.6	-1.5	0.1	-1.6	-1.4	-0.6	-1.7	-1.8	-1.5	-1.0	-1.2	-1.9	-1.5	-1.2	-1.2	-1.4	-1.2	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.8	3.8	1.1	1.6	0.1	1.3	1.1	1.7	1.7	1.6	1.8	0.3	1.1	2.0	1.2	1.3	1.3	1.8	1.5	-1.0
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	6.2	1.4	1.4	2.2	1.4	2.5	1.6	1.4	1.3	1.0	1.1	1.1	1.4	1.0	1.0	0.9	1.7	0.7	-0.8
Impedance of arm (left)	1.4	6.6	17.7	-4.2	-2.7	-0.1	-2.2	-2.1	-2.1	-2.4	-2.5	-2.4	-2.1	-1.6	-3.9	-2.4	-2.8	-2.8	-1.4	-2.3	-4.2
Wheeze or whistling in the chest in last year	1.4	2.4	5.9	1.6	1.6	0.5	1.8	2.4	1.1	2.0	2.0	1.5	1.3	1.7	1.5	1.6	1.5	1.5	2.0	1.3	-0.4
Heart disease (mother)	1.4	1.7	3.1	1.6	1.7	-0.3	1.1	1.3	1.0	1.1	1.8	1.1	0.9	1.7	1.2	1.4	1.5	1.2	1.8	0.9	1.5
Overall health rating	1.4	3.1	13.2	1.9	2.3	0.4	2.3	1.5	0.0	1.9	1.8	2.0	0.5	1.0	3.6	2.1	2.3	1.5	1.3	1.3	0.8
Chest pain or discomfort	1.4	2.0	5.6	0.7	1.4	0.7	1.3	2.1	2.4	1.9	1.2	1.7	0.4	1.0	1.6	1.0	1.0	1.4	2.3	1.3	-0.4
Family relationship satisfaction	1.4	1.7	5.8	-1.1	-1.3	-0.7	-1.0	-1.1	-0.5	-1.5	-1.3	-1.8	-2.4	-1.9	-1.1	-1.7	-1.6	-1.3	-1.3	-0.5	0.1
Illnesses of siblings: Diabetes	1.4	1.8	3.2	-1.1	-1.4	-1.8	-1.2	-1.0	-1.8	-1.3	-1.7	-1.2	-0.3	-1.4	-1.2	-1.0	-1.5	-1.4	-1.6	-1.4	-1.6
Eye problems/disorders: Cataract	1.4	1.7	3.0	-1.5	-1.6	-0.9	-1.1	-1.2	-1.0	-1.4	-1.7	-1.4	-1.4	-1.6	-1.3	-1.4	-1.3	-1.4	-1.7	-0.8	0.1
Heart disease (siblings)	1.4	1.7	4.9	2.2	1.6	0.1	0.9	1.4	0.3	1.1	1.7	0.9	2.0	1.9	0.7	1.6	1.4	1.3	1.1	1.2	0.3
Medication: Atenolol	1.3	1.6	2.9	-0.3	1.7	0.1	1.4	1.1	0.1	1.6	1.3	1.7	1.7	1.4	1.7	1.7	1.4	1.5	1.2	0.5	-0.9
Impedance of arm (right)	1.3	6.1	15.4	-3.7	-2.7	-0.1	-2.1	-2.0	-1.7	-2.5	-2.5	-2.5	-1.9	-1.6	-3.9	-2.5	-2.8	-2.8	-1.4	-2.0	-3.8
Length of working week for main job	1.3	1.4	3.9	2.0	1.5	0.6	1.1	0.9	0.9	1.2	1.2	1.5	1.8	1.1	1.6	1.4	1.3	0.9	0.8	0.5	0.6
Chronic bronchitis/emphysema (mother)	1.3	1.5	4.1	1.7	1.6	0.8	1.1	1.1	-0.5	1.1	1.7	0.9	0.7	1.5	1.4	1.6	2.0	1.3	0.3	0.7	1.3
Smoking status: Previous	1.3	2.0	3.4	0.0	1.8	1.7	1.5	1.8	1.2	1.7	1.6	1.5	1.0	1.4	1.5	1.5	1.8	1.7	1.4	1.1	0.0
Age started oral contraceptive pill	1.3	1.7	4.6	-1.6	-1.0	-1.4	-2.1	-0.4	-1.1	-1.4	-1.4	-1.2	-1.6	-0.8	-1.6	-1.1	-1.4	-1.2	-1.5	-0.5	-1.3
Cardiovascular Disease	1.2	4.0	9.5	1.4	2.8	1.1	2.3	1.9	0.8	2.0	2.4	2.3	2.3	2.7	2.4	3.1	2.4	2.2	1.7	0.5	0.6
Relative age of first facial hair	1.2	2.6	7.9	-2.8	-1.8	-1.2	-1.8	-2.0	-1.7	-1.1	-1.9	-1.1	-1.7	-1.4	-1.6	-1.4	-1.6	-1.5	-1.2	-1.4	-1.5
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	2.7	-1.1	1.2	0.6	1.6	1.4	0.9	1.6	1.1	1.2	1.6	1.6	0.7	1.4	1.6	1.6	0.9	1.1	0.4
Qualifications: A levels/AS levels or equivalent	1.2	2.7	6.1	-2.2	-1.7	-2.0	-1.8	-1.8	-2.5	-1.5	-1.5	-1.6	-1.3	-1.0	-2.0	-1.4	-1.5	-1.8	-1.7	-1.5	-0.7
Medication: Cholesterol lowering	1.2	1.9	5.2	1.1	1.5	2.3	1.4	1.5	0.9	1.4	1.7	0.7	1.1	1.7	1.1	1.4	1.5	1.2	1.6	1.1	1.6
Qualifications: O levels/GCSEs or equivalent	1.2	2.0	4.9	-1.1	-1.8	-0.0	-0.9	-1.0	-1.3	-1.9	-1.5	-1.8	-1.0	-1.6	-2.0	-2.2	-1.2	-2.2	-1.0	-1.0	-0.4
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	3.9	-2.0	-1.7	-1.4	-1.5	-1.7	-1.0	-1.2	-1.9	-0.5	-0.8	-1.5	-1.2	-1.1	-1.8	-0.9	-1.7	-1.6	-1.7
Exposure to tobacco smoke outside home	1.2	1.7	4.4	1.0	-1.3	-0.2	-0.9	-0.8	-1.5	-1.9	-1.1	-2.1	-0.8	-1.5	-0.8	-1.0	-1.4	-1.8	-1.9	-1.2	-1.2
Pulse wave peak to peak time	1.2	1.4	5.0	0.5	1.4	0.3	0.9	2.2	1.2	1.6	1.5	1.0	0.5	1.5	0.9	0.9	0.9	1.0	1.8	1.4	-0.5
Mouth/teeth dental problems: Loose teeth	1.2	1.4	3.2	0.1	1.7	0.6	1.2	0.6	-0.2	1.6	1.3	1.5	0.7	1.0	1.8	1.6	1.5	1.5	0.8	1.0	1.0
Supplements: Vitamin C	1.2	1.4	5.3	1.1	-1.0	-1.0	-0.9	0.9	0.2	-1.2	-0.7	-2.3	-1.1	-1.2	-1.3	-2.1	-1.0	-1.3	-0.6	0.6	1.7
Ever had bowel cancer screening	1.2	1.4	4.4	-0.6	-1.2	-0.5	-1.0	-2.1	-0.3	-1.7	-1.4	-1.4	-1.4	-1.6	-0.8	-1.4	-1.3	-1.0	-1.3	-0.3	-0.3
Friendships satisfaction	1.2	1.5	4.3	-0.6	-1.6	-1.6	-1.3	-0.4	-0.1	-1.1	-1.6	-1.6	-1.3	-1.4	-1.0	-1.3	-2.1	-1.5	-1.0	-0.6	-0.8
Mineral and other dietary supplements	1.2	1.6	3.8	0.7	1.3	0.9	1.2	1.7	0.9	1.6	1.2	1.9	1.5	1.5	0.7	1.6	1.6	1.7	1.0	0.9	-0.3
Commuting to job workplace: Public transport	1.2	1.4	4.2	-0.7	-1.3	-0.7	-0.9	-1.7	-0.7	-1.5	-1.2	-1.4	-2.0	-1.4	-1.2	-1.6	-1.4	-1.4	-1.0	-0.0	-0.3
Medication: Bendroflumethiazide	1.2	1.8	4.5	1.6	1.8	0.8	1.9	0.8	0.5	1.0	1.8	1.2	0.9	1.0	1.6	1.2	2.1	1.4	1.2	1.5	1.3
Worry (Nagel 2018)	1.1	2.3	6.0	1.0	1.7	0.0	1.2	2.1	2.2	2.0	1.8	1.5	0.9	2.2	0.7	1.3	1.0	1.7	2.4	1.3	0.4
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.3	0.6	1.3	1.0	1.5	1.3	1.4	1.1	1.1	0.9	0.3	0.6	1.5	1.0	1.4	0.8	1.1	1.2	1.1
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	4.5	0.7	1.6	-0.4	1.2	1.1	0.1	1.9	1.6	1.6	1.4	1.8	1.8	2.1	1.0	1.3	1.1	0.3	-1.5
Pulse wave Arterial Stiffness index	1.1	1.3	4.2	-0.3	-1.4	-0.5	-1.0	-2.0	-0.9	-1.6	-1.5	-1.0	-0.4	-1.4	-1.1	-1.0	-1.0	-0.9	-1.7	-1.4	0.4
Medication for cholesterol	1.1	1.7	3.3	-1.3	-1.8	-1.0	-1.6	-1.6	-0.5	-1.2	-1.6	-1.2	-1.5	-1.3	-1.7	-1.8	-1.4	-1.3	-1.0	0.0	-0.0
Unable to work because of sickness or disability	1.1	1.4	3.0	1.7	1.5	-0.2	1.3	1.5	1.4	1.3	1.4	1.1	0.2	1.2	1.5	1.2	1.1	1.2	1.3	1.0	0.4
Impedance of whole body	1.1	5.6	19.4	-3.3	-2.3	-0.2	-2.1	-1.7	-1.9	-2.3	-2.0	-2.4	-2.2	-1.4	-3.6	-2.3	-2.7	-2.8	-0.9	-2.0	-4.4
Diabetes (father)	1.0	1.3	2.7	0.3	-1.3	-0.8	-1.0	-0.8	-0.4	-1.2	-0.9	-1.7	-1.5	-1.4	-1.0	-1.5	-1.2	-1.6	-0.8	-1.5	0.9
Chronic bronchitis/emphysema (father)	1.0	1.2	5.7	1.4	1.0	0.7	0.6	1.3	1.2	1.1	1.0	0.8	2.4	1.4	0.6	1.0	0.4	0.8	1.3	0.5	1.1
Number of live births	1.0	1.4	2.8	0.9	1.2	0.6	1.1	1.6	1.0	1.7	1.1	1.5	1.5	1.5	0.9	1.7	1.2	1.3	1.2	0.4	-0.2
Alcohol intake frequency.	1.0	2.3	4.0	-0.5	-1.6	-1.4	-2.0	-1.1	-1.2	-1.9	-2.0	-1.5	-1.7	-2.0	-1.3	-1.7	-1.4	-1.9	-1.8	-1.2	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	4.5	-2.1	-1.4	-1.1	-1.1	-0.5	-0.5	-0.5	-1.6	-0.9	-0.4	-1.0	-1.2	-1.0	-1.4	-1.3	-0.6	-1.6	0.2
Miserableness	1.0	1.7	6.6	1.0	1.1	0.5	0.9	1.9	2.0	1.6	1.5	1.3	0.9	1.9	-0.0	0.7	0.5	1.2	2.6	1.3	-0.7
Alcohol drinker status: Never	1.0	1.2	4.6	-0.5	-1.1	-1.7	-1.4	-0.7	0.1	-1.6	-1.1	-1.4	-0.7	-0.5	-2.1	-1.4	-0.8	-0.9	-1.0	-0.2	0.9
Lung FVC	0.9	4.5	17.0	-2.3	-2.1	-0.5	-1.8	-1.5	0.1	-2.7	-1.8	-3.0	-1.3	-1.8	-4.1	-3.9	-1.9	-2.6	-0.5	-0.0	-1.8
Heel bone mineral density (BMD) T-score, automated (left)	0.9	1.9	5.0	-0.2	-1.5	-2.2	-1.8	-0.6	-1.9	-1.0	-1.3	-1.8	-0.5	-1.5	-1.8	-1.8	-1.4	-1.7	-1.1	-0.2	-0.8
High blood pressure	0.9	2.5	6.8	1.2	2.3	0.2	1.8	1.5	-0.1	1.8	1.7	1.8	1.6	1.8	2.3	2.6	1.9	1.5	1.3	-0.2	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	4.0	-1.0	-1.6	-1.5	-1.6	-0.7	-1.9	-1.1	-1.3	-2.0	-0.4	-1.5	-1.9	-1.7	-1.7	-1.7	-1.4	-0.4	-1.7
Qualifications: None of the above	0.9	1.8	5.6	2.4	1.5	-0.6	1.2	1.1	1.5	1.5	1.5	1.3	-0.0	0.6	2.0	1.0	1.2	1.4	1.4	2.2	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	5.5	0.5	0.5	1.6	1.0	2.3	0.4	1.3	0.8	0.6	2.2	1.0	0.4	0.8	0.6	0.7	1.3	0.3	1.0
Headache pain in last month	0.9	1.6	4.6	1.3	1.3	0.5	1.6	0.6	0.1	1.6	1.1	1.6	2.1	1.2	1.8	2.0	0.6	1.4	0.5	0.1	-1.3
Medication: Atorvastatin	0.9	1.2	3.2	1.6	1.0	1.8	1.1	1.4	1.5	0.7	1.3	0.6	-0.6	0.6	0.2	0.1	1.1	0.7	1.3	1.5	0.8
Depression (Nagel 2018)	0.8	1.2	3.2	0.2	1.4	-0.4	0.7	0.9	1.4	1.3	1.3	1.4	0.9	1.0	1.3	1.0	0.7	1.1	1.4	0.8	-1.8
Alzheimer’s Disease (in mother)	0.8	0.9	3.1	1.0	1.0	0.9	0.9	1.8	1.1	0.9	0.9	0.5	0.5	0.0	1.3	0.2	1.6	0.4	1.1	1.0	0.4
Heel T-Score	0.8	6.2	16.0	-1.3	-3.1	-2.7	-3.0	-1.9	-3.1	-2.3	-2.9	-3.9	0.0	-2.1	-4.0	-3.1	-2.8	-2.7	-1.8	-1.1	0.0
Average weekly spirits intake	0.8	1.0	4.3	2.1	0.9	0.0	0.9	1.7	0.2	0.9	1.2	-0.1	1.4	1.3	0.5	1.0	0.7	0.8	0.3	0.9	1.0
Relative age voice broke	0.8	1.2	6.9	-2.6	0.9	0.6	1.1	0.0	-0.1	1.5	0.5	1.6	1.3	0.9	0.8	1.1	1.5	1.2	0.7	0.1	-0.6
Supplements: Glucosamine	0.8	1.1	2.8	0.2	-0.9	-0.8	-1.2	-1.2	-0.9	-1.1	-0.8	-1.6	-1.3	-1.6	-0.2	-1.7	-1.1	-1.5	-0.7	-0.5	-0.2
Allergy	0.8	1.8	6.4	0.7	-1.3	-2.5	-1.8	-1.0	-0.4	-1.3	-1.4	-1.5	-2.1	-1.3	-1.0	-1.6	-1.7	-1.3	-0.7	-0.3	0.9
Worry too long after embarrassment	0.8	1.3	3.1	-0.5	-1.3	-1.5	-1.0	-0.8	-1.0	-0.9	-1.2	-1.1	-1.5	-0.8	-1.3	-0.9	-1.8	-1.1	-0.9	-1.5	-1.4
Number of children fathered	0.8	0.9	3.9	-0.5	-0.7	0.1	-1.3	-0.9	-0.9	-1.1	-0.7	-0.9	-0.2	-0.5	-1.1	-0.8	-1.0	-1.0	-0.7	-1.1	-2.0
Neck or shoulder pain in last month	0.8	1.2	3.0	0.2	-1.5	-1.1	-1.1	-0.7	-1.3	-1.0	-1.3	-1.7	-0.2	-1.1	-1.2	-1.1	-1.4	-1.4	-1.2	-1.1	0.0
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	2.8	0.6	-0.6	0.5	-1.0	-1.2	-0.4	-1.7	-0.9	-0.8	-1.5	-1.1	-1.4	-1.6	-0.3	-0.6	-0.9	0.2	1.2
Hypertension (Self-reported)	0.8	2.1	5.7	1.0	2.1	0.5	1.7	1.3	-0.1	1.6	1.6	1.7	1.5	1.7	2.1	2.4	1.7	1.5	1.2	-0.2	-0.0
Alcohol drinker status: Previous	0.8	0.9	2.4	-0.6	-0.8	0.1	-1.2	-0.3	-1.1	-1.3	-0.9	-1.2	-0.6	-1.1	-0.7	-1.1	-1.0	-1.5	-0.9	-1.1	-1.0
Verbal and Numeric Reasoning (VNR)	0.7	1.7	5.3	-1.8	-1.5	-0.5	-1.7	-0.7	0.2	-1.4	-1.4	-1.4	-2.3	-1.2	-1.9	-2.0	-1.1	-1.4	-0.5	-0.3	0.5
Ovarian Cancer	0.7	0.9	4.8	1.9	0.5	-0.1	0.5	2.2	0.5	1.3	0.5	0.7	0.7	0.8	1.1	1.2	0.2	0.6	0.8	-0.0	1.4
Respiratory disease	0.7	1.6	4.6	0.2	1.1	2.1	1.9	2.0	2.1	1.2	1.4	0.6	1.5	1.2	0.5	0.8	1.1	1.1	1.0	0.7	0.3
Chronotype (morning person)	0.7	1.7	5.6	2.4	-0.8	-1.2	-1.2	0.9	-0.3	-1.5	-0.5	-1.9	-1.8	-1.0	-1.7	-2.0	-0.5	-1.3	-0.5	0.5	1.4
Number of treatments/medications taken	0.7	1.2	3.8	1.2	0.9	1.0	1.7	1.8	0.6	1.3	1.0	0.6	1.9	0.9	1.4	1.3	0.9	0.6	1.1	-0.0	0.6
Hearing difficulty/problems: Yes	0.7	1.0	4.6	-2.2	0.7	-0.5	-0.1	-1.0	-1.9	0.0	-0.0	0.6	-0.9	0.6	0.5	1.3	0.4	0.8	-0.9	-0.4	-1.9
Systolic blood pressure, automated reading	0.7	2.0	8.5	1.0	1.7	-1.2	1.0	-0.3	-0.4	1.5	0.9	1.9	-0.4	0.9	2.9	2.2	1.0	0.7	1.3	0.7	-2.5
Maternal smoking around birth	0.7	1.0	3.3	0.1	1.1	0.5	0.9	0.1	-1.8	0.7	0.8	1.1	1.1	0.7	1.8	1.8	0.7	0.5	-0.2	-0.9	-0.9
Age when periods started (menarche)	0.7	1.6	6.7	0.9	0.6	1.2	0.5	2.3	2.6	1.4	1.0	1.0	1.7	1.3	-0.1	0.4	0.0	0.9	2.2	0.5	-1.4
Hayfever, allergic rhinitis or eczema	0.7	1.5	8.5	-1.2	1.0	2.9	1.5	0.2	0.1	1.0	1.1	1.3	1.9	1.0	0.7	1.2	1.2	0.9	0.2	-0.2	-1.4
Nervous feelings	0.7	1.3	6.6	1.2	0.9	-0.5	1.1	2.6	1.6	1.4	1.1	0.8	-0.2	1.1	0.5	0.8	0.6	0.8	1.7	0.8	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	3.8	2.0	1.2	-0.6	0.5	1.6	0.8	1.2	1.1	1.3	0.1	1.1	1.2	1.2	0.6	0.9	1.4	0.7	-0.2
Hearing difficulty/problems with background noise	0.7	1.1	5.6	-2.1	0.4	-1.3	-0.3	-0.8	-1.9	0.4	-0.4	0.9	-0.9	0.1	1.0	1.0	0.1	0.2	-0.4	-1.0	-2.4
Financial difficulties in last 2 years	0.7	1.0	3.3	0.2	0.9	0.8	1.5	0.6	0.2	1.3	0.9	1.2	0.8	0.9	1.8	1.7	0.9	0.9	0.7	-0.2	-0.8
Hair/balding pattern: Pattern 3	0.7	1.1	4.0	-1.4	-1.0	-0.5	-1.0	-2.0	-0.4	-1.1	-0.9	-0.6	-0.7	-0.8	-1.2	-1.0	-1.0	-0.7	-1.4	-0.6	-1.4
Mouth/teeth dental problems: Dentures	0.7	1.1	2.6	1.5	1.1	0.7	1.1	0.8	0.8	1.1	1.1	0.9	1.5	1.0	1.6	1.5	1.0	1.1	0.5	0.9	-0.2
Breastfed as a baby	0.7	0.8	8.3	-2.9	-0.4	0.4	-0.0	-0.8	-0.7	-0.0	-0.8	-0.0	1.4	-0.2	-0.2	0.1	0.1	0.7	-0.9	-1.2	-0.4
Forced vital capacity (FVC), Best measure	0.7	2.6	15.4	-2.1	-1.9	-0.7	-1.8	-0.5	1.6	-1.1	-1.6	-1.8	-0.4	-0.7	-3.9	-2.7	-1.9	-0.9	0.2	0.2	0.1
Medication: Omeprazole	0.7	0.8	2.1	-0.7	-1.0	-0.7	-1.0	0.2	-0.0	-0.8	-1.0	-1.3	-1.2	-0.9	-0.9	-1.2	-1.2	-1.4	-0.4	-0.5	-0.4
Knee pain experienced in last month	0.7	1.1	6.6	1.8	1.0	-0.2	0.9	0.7	-1.1	1.2	0.7	1.2	1.3	0.0	2.6	1.3	0.8	0.5	0.3	0.1	-0.3
Qualifications: nursing, teaching	0.7	1.0	5.8	-0.8	-0.7	0.6	-1.1	-0.9	-0.6	-1.1	-0.0	-1.6	-1.0	0.4	-2.4	-1.2	-0.6	-0.6	0.0	0.0	1.7
Osteoporosis (self-reported)	0.7	0.9	4.6	1.0	1.2	2.1	1.4	0.6	-0.1	0.3	1.1	0.5	0.1	0.3	1.4	0.5	1.3	0.5	1.1	0.1	-0.1
Medication: Paracetamol	0.7	1.0	7.0	2.6	0.6	0.4	1.1	0.7	1.7	0.7	1.1	-0.1	1.1	0.6	0.9	0.4	0.2	0.5	1.1	0.9	-0.7
Ever smoked	0.7	1.3	2.7	0.4	1.4	-0.1	1.1	1.2	1.0	1.6	1.2	1.3	0.6	1.2	1.2	1.3	1.4	1.6	1.3	1.1	0.4
Intelligence (Savage-Jansen 2018)	0.6	1.8	4.8	-1.8	-1.3	0.1	-1.5	-1.8	-0.3	-1.4	-1.1	-1.3	-2.1	-1.2	-2.2	-2.2	-0.9	-1.4	-0.2	-0.0	-0.4
Alzheimer’s Disease (in father)	0.6	0.7	2.8	-1.2	-1.0	-0.5	0.2	-0.4	-1.1	-0.4	-1.2	-0.4	0.5	-1.2	0.1	-0.2	-0.5	-0.8	-1.3	-1.7	-0.1
Irritable Bowel Disease (IBD)	0.6	1.5	6.8	0.8	0.0	2.1	2.0	2.6	0.8	1.1	0.0	1.0	1.5	0.0	0.0	0.0	1.3	0.7	2.0	1.2	-0.8
Vitamin and mineral supplements	0.6	0.7	8.6	-1.2	0.2	-0.9	-0.8	-0.1	-0.7	0.4	-0.1	1.0	0.4	0.2	-0.4	0.4	0.5	0.4	-0.4	-0.4	-2.9
Townsend deprivation index at recruitment	0.6	0.8	8.6	2.9	0.5	-1.0	0.3	1.2	0.7	0.7	0.4	0.2	0.5	0.3	1.0	0.7	0.2	0.3	0.1	0.6	-0.7
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	4.7	1.2	0.9	0.3	0.6	0.2	-0.2	0.1	0.8	-0.0	-1.0	-0.0	1.0	0.1	1.3	0.2	0.4	2.2	0.4
Impedance of leg (left)	0.6	3.1	9.9	-1.3	-1.6	-0.8	-1.7	-0.9	-1.1	-1.9	-1.2	-2.3	-1.6	-0.8	-2.8	-1.8	-2.3	-2.4	-0.6	-1.4	-3.1
Had other major operations	0.6	0.7	3.8	-2.0	-0.9	0.4	-0.1	0.4	-0.8	-0.0	-1.2	0.1	0.3	-1.1	0.2	-0.2	-0.6	-0.7	-0.6	-1.9	-0.5
Heart attack	0.6	0.8	2.2	-0.0	1.0	-0.2	0.3	0.6	0.2	1.1	0.9	1.0	0.8	1.4	1.1	1.5	0.2	0.8	1.3	-0.7	-1.4
Pain all over the body in last month	0.6	0.6	4.0	-0.8	-0.7	-0.7	-0.6	-1.4	0.1	-0.9	-0.6	-0.9	-0.3	-0.2	-0.8	-0.5	-0.5	-0.2	-0.4	-0.3	2.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	9.4	-2.5	-1.6	-0.2	-1.5	-0.5	0.8	-0.9	-1.6	-1.2	0.1	-0.9	-3.1	-2.3	-1.4	-0.9	0.2	-0.3	-0.4
Peak expiratory flow (PEF)	0.6	1.4	6.5	-2.2	0.6	2.2	1.2	1.0	0.5	1.6	0.3	1.0	2.5	0.2	1.0	0.5	0.9	1.0	0.7	0.4	-0.2
Shortness of breath walking on level ground	0.6	0.7	2.2	1.5	1.0	-1.1	0.4	1.2	0.7	0.8	0.7	0.4	-0.6	0.2	1.3	0.6	0.8	0.4	0.6	1.5	-0.7
Medication: Allopurinol	0.6	0.8	3.6	1.9	0.7	-0.3	1.0	1.5	1.1	0.7	0.8	0.7	0.1	1.0	-0.3	0.5	0.5	1.0	0.9	1.0	0.5
Had major operations	0.6	0.7	3.3	0.9	0.6	1.1	0.7	0.8	-0.7	0.2	0.3	0.6	0.9	0.3	0.3	0.5	1.8	0.4	-0.0	0.0	1.8
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.1	-0.2	-1.1	-0.4	-0.5	-1.4	-0.3	-1.3	-0.8	-1.4	-0.4	-0.7	-1.1	-1.0	-0.8	-0.7	-1.3	-0.3	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.5	1.2	0.4	0.0	0.2	1.6	-0.3	0.9	0.4	0.4	1.2	0.8	0.9	1.3	-0.2	0.3	0.5	-0.5	-1.0
Tinnitus: Yes, now most or all of the time	0.6	0.7	3.1	0.2	0.7	-0.5	0.3	-0.1	-1.2	0.5	0.1	1.3	1.8	0.8	1.0	1.5	0.9	0.8	-0.4	-0.6	-0.5
Risk taking	0.6	0.8	3.3	1.8	0.8	0.7	0.5	1.8	0.5	0.6	0.8	0.2	-0.3	0.5	0.3	0.1	1.0	0.5	0.9	1.8	0.8
Myopia	0.6	0.9	2.2	-0.8	-1.1	-1.0	-1.1	-1.5	-0.9	-1.1	-1.2	-1.0	-0.6	-1.2	-0.9	-1.2	-0.8	-0.8	-0.9	-0.4	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.0	-0.5	-0.9	-0.8	-1.0	0.6	0.2	-0.5	-0.9	-1.1	-1.4	-0.8	-0.8	-1.1	-1.1	-1.3	-0.2	-0.2	-0.5
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.1	0.2	1.0	-0.2	0.2	0.6	0.2	1.0	0.9	1.0	1.0	1.4	1.1	1.4	0.2	0.7	1.2	-0.8	-1.2
Severe depression (siblings)	0.5	0.6	3.0	1.7	0.4	0.4	0.7	0.8	1.4	0.7	0.6	0.1	0.5	0.6	1.1	0.9	-0.3	0.3	0.2	-0.1	-0.3
Impedance of leg (right)	0.5	2.6	10.2	-1.6	-1.5	0.4	-1.3	-0.7	-0.5	-1.6	-0.9	-2.3	-1.3	-0.5	-3.2	-1.9	-2.0	-2.1	-0.2	-0.8	-2.8
Fed-up feelings	0.5	0.8	3.7	-0.7	0.7	0.4	0.9	0.6	0.5	1.4	0.6	1.6	1.1	0.8	0.5	0.8	0.4	1.0	1.0	-0.0	-1.9
Qualifications: CSEs or equivalent	0.5	0.7	4.2	2.1	0.5	0.1	0.8	0.1	-0.6	0.4	0.5	1.1	1.6	0.2	1.1	0.9	0.6	0.2	0.4	-0.5	-0.4
Stomach or abdominal pain in last month	0.5	0.6	1.4	0.1	-1.0	-0.0	-1.1	0.6	-0.1	-0.3	-0.9	-1.0	-0.7	-1.0	-1.0	-1.1	-1.2	-1.1	-0.2	-0.1	-0.9
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.4	-0.3	-0.9	-0.2	-0.1	-0.4	-1.2	-1.0	-0.8	-1.1	-0.5	-0.8	-0.4	-0.5	-0.6	-1.0	-1.0	-1.2	0.0
Hair/balding pattern: Pattern 2	0.5	0.6	1.3	0.4	-0.9	-1.0	-0.5	-0.2	-1.0	-1.0	-1.1	-1.0	-0.0	-0.6	-1.0	-0.5	-0.5	-0.8	-1.0	-0.2	1.1
Forced vital capacity (FVC)	0.5	1.9	11.6	-1.9	-1.5	-0.6	-1.2	-0.2	1.9	-0.8	-1.4	-1.4	0.4	-0.4	-3.4	-2.2	-1.6	-0.6	0.3	0.1	0.1
Time employed in main current job	0.5	0.6	6.0	-0.3	-0.4	-0.9	-0.1	0.7	0.1	0.1	-0.6	0.4	1.6	0.3	-0.6	0.3	0.1	0.3	-0.6	-0.3	2.4
Medication: Blood pressure	0.5	0.8	3.4	1.8	0.9	0.4	0.8	1.5	0.9	0.6	1.2	0.1	-0.3	0.7	0.6	0.1	0.8	0.1	1.6	0.8	1.0
Medication: Seretide 50 evohaler	0.5	0.5	2.1	-1.1	0.6	-0.0	0.5	0.5	0.2	1.2	0.2	1.1	0.3	0.4	1.5	1.1	0.6	0.4	0.7	-0.4	-0.8
Medication: Gliclazide	0.5	0.6	1.4	-0.2	0.8	0.3	0.6	1.0	0.4	1.2	0.7	0.9	1.0	0.8	1.2	1.1	0.7	0.8	0.8	0.7	0.1
Medication: Lisinopril	0.5	0.7	4.8	2.2	0.3	-0.9	0.7	0.5	0.5	0.5	0.5	0.1	0.4	-0.2	1.6	0.5	0.3	-0.0	0.5	0.2	-1.4
Number of operations (self-reported)	0.5	0.7	3.9	-1.3	0.2	2.0	1.1	-0.0	-0.4	0.3	-0.3	0.3	1.7	0.3	0.8	1.0	0.8	0.4	-0.6	-0.8	0.2
Irritability	0.5	0.9	6.6	0.2	0.6	0.2	0.6	2.6	2.1	1.2	0.6	0.5	0.8	0.7	0.2	0.4	0.3	0.8	1.0	0.9	-0.0
Pain experienced in last month	0.5	0.8	3.5	0.1	0.7	1.9	0.7	0.6	1.8	0.2	1.0	0.5	-1.3	0.8	0.3	0.2	0.7	0.6	1.1	0.4	0.6
Lupus	0.4	0.6	3.6	1.9	0.0	0.2	-1.2	0.6	0.7	-0.5	-0.0	-0.5	-0.9	-0.1	0.0	0.0	-1.4	-0.8	0.1	-0.5	-1.4
Smoking Status	0.4	1.0	3.4	0.5	1.2	0.2	1.2	1.0	0.4	1.5	1.1	0.8	1.5	0.9	1.8	1.5	0.9	0.9	0.4	0.6	-0.5
Lung FEV1/FVC ratio	0.4	1.9	6.4	-0.7	1.5	1.8	1.8	0.2	-2.0	1.3	0.8	1.9	1.2	0.5	2.5	1.8	2.1	1.1	0.4	0.5	0.2
Pack years adult smoking proportion	0.4	0.6	3.9	2.0	0.7	-0.6	0.8	0.5	0.1	0.6	0.8	0.1	-0.3	0.2	1.8	0.9	0.4	0.2	0.1	0.3	-0.4
Average weekly fortified wine intake	0.4	0.5	3.3	-1.5	0.3	-0.4	0.3	-1.8	-0.2	-0.0	0.5	0.6	0.8	0.3	0.3	0.2	0.5	0.6	0.2	0.2	-1.0
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	2.0	-0.9	-0.6	0.1	0.3	-1.4	-1.3	-0.3	-0.9	-0.3	0.5	-0.7	0.2	0.1	-0.5	-0.2	-1.3	-0.4	-0.7
Multivitamins +/- minerals	0.4	0.5	4.9	0.8	0.2	0.6	1.2	-0.3	0.6	0.4	0.3	0.0	0.6	0.4	0.8	0.6	-0.2	0.4	0.5	0.2	2.2
High blood pressure (mother)	0.4	0.5	6.8	0.2	0.2	-0.9	0.0	0.1	-0.5	0.5	0.0	0.2	-0.1	0.0	0.9	0.6	-0.3	-0.5	0.3	-0.7	-2.6
Number of incorrect matches in round	0.4	0.7	4.0	0.5	0.4	-1.2	0.2	1.2	1.3	0.9	0.0	0.6	0.4	0.2	0.8	0.5	0.0	0.6	0.8	0.4	2.0
Mouth/teeth dental problems	0.4	0.5	2.0	-0.3	-0.9	-0.5	-1.0	0.6	-0.3	-0.9	-0.6	-0.5	-1.0	-0.7	-1.4	-1.4	-0.4	-0.9	0.2	-0.2	0.3
Worrier / anxious feelings	0.4	0.7	4.5	0.6	0.5	-0.2	0.6	1.0	2.1	1.1	0.9	0.6	0.2	1.0	0.0	0.2	-0.2	0.8	1.5	0.6	0.0
Pulse rate	0.4	0.7	2.1	-0.5	-1.0	-0.0	-0.8	-1.0	-0.4	-1.1	-1.4	-0.7	-0.2	-0.7	-1.3	-0.8	-0.6	-0.8	-0.7	-0.9	0.8
Happiness	0.4	0.5	1.4	0.7	-0.5	-0.9	-0.6	-0.5	-0.0	-0.8	-0.5	-0.7	-1.2	-1.0	-0.2	-1.0	-0.9	-0.9	-0.1	0.2	-0.9
Standing height	0.4	4.0	24.4	1.7	0.3	0.2	0.9	2.8	4.9	1.8	0.7	0.6	1.7	1.6	-2.1	-0.3	0.4	2.4	2.3	2.8	2.8
Exposure to tobacco smoke at home	0.4	0.5	1.6	1.0	0.9	-1.3	-0.0	0.4	-0.3	0.9	0.3	0.8	0.2	0.6	0.8	1.0	0.5	0.4	0.5	0.2	-0.8
Birth weight	0.4	0.8	1.7	-1.1	-0.6	-0.9	-1.2	-1.1	-1.3	-0.9	-0.9	-0.4	1.2	-0.5	-1.0	-0.8	-0.4	-0.8	-0.3	-1.1	1.0
Comparative body size at age 10	0.4	1.1	5.3	0.0	-0.4	0.6	0.0	-2.0	-1.4	-1.0	-1.0	-0.2	-0.3	-1.2	0.9	-0.0	0.5	0.1	-2.0	-1.1	2.3
Number of full brothers	0.4	0.5	1.9	1.4	0.4	-0.3	0.6	1.3	0.5	0.8	0.8	0.6	1.0	0.3	1.0	0.4	0.5	0.5	0.6	0.6	0.4
Age at first live birth	0.4	0.8	2.3	-0.8	-0.6	-0.2	-0.6	-1.1	-0.7	-1.3	-0.2	-1.0	-1.3	-0.7	-1.5	-1.4	0.4	-0.6	-0.6	1.1	-0.7
Medication: Ibuprofen	0.4	0.5	3.6	0.4	0.1	1.0	0.7	1.9	0.1	0.9	0.5	0.1	1.6	0.4	0.2	0.4	0.2	0.3	0.7	-0.1	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	1.3	-0.8	0.4	0.6	1.0	-0.7	0.3	0.6	0.2	0.9	1.0	0.5	0.9	1.2	0.3	0.8	0.0	-0.6	-0.1
Average weekly red wine intake	0.4	0.5	2.6	-1.0	-0.3	-0.2	-1.0	-0.5	-0.5	-0.9	-0.0	-1.0	-0.3	0.3	-1.6	-0.7	-0.4	-0.5	-0.5	-0.5	-1.2
Commuting to job workplace: Walk	0.4	0.4	1.5	-0.9	-0.2	0.3	-0.5	-0.6	-0.4	-0.8	-0.0	-1.0	-0.3	-0.3	-1.2	-1.1	-0.3	-0.3	-0.3	0.8	-0.5
Breast cancer (self-reported)	0.4	0.5	2.6	0.1	-0.3	-0.9	0.1	0.9	0.2	0.2	-0.8	-0.0	-1.6	-0.9	0.6	-0.1	-0.3	-0.8	0.2	-0.2	1.4
Smoking status: Current	0.4	0.7	2.8	1.7	0.8	-0.5	1.0	0.5	0.2	0.8	0.9	0.2	1.1	0.9	1.1	1.1	0.7	0.7	0.4	1.0	0.4
Financial situation satisfaction	0.4	0.4	1.6	-0.1	-0.3	-1.3	-0.1	-1.2	-0.5	-0.5	-0.3	-0.5	-0.7	-0.2	-0.1	0.2	-0.5	-0.3	-1.0	-1.0	-1.2
High cholesterol (Self-reported)	0.4	0.8	4.2	-0.5	0.7	2.1	1.2	-0.7	-0.9	0.4	0.5	0.4	0.9	0.5	1.4	1.2	0.8	0.4	-0.3	-0.6	0.4
Average weekly beer plus cider intake	0.4	0.6	2.6	1.1	0.4	0.6	1.2	0.9	-0.3	0.9	-0.0	1.0	0.4	-0.0	1.6	1.0	0.8	0.5	0.4	-0.2	1.0
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.6	-1.1	-0.3	0.7	-0.3	-1.1	-0.0	-0.8	-0.2	-0.9	-0.2	-0.3	-1.0	-0.9	-0.4	0.0	-0.4	0.5	1.6
Breast Cancer	0.3	0.8	3.2	-0.3	-0.0	-0.6	-0.5	1.3	1.2	1.4	-0.2	1.1	1.8	0.9	-0.3	0.7	-0.6	0.6	0.9	-0.9	-1.1
Fasting Glucose	0.3	0.4	2.2	0.6	0.0	0.6	1.1	0.8	0.5	0.6	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	1.5
Blood Eosinophil Count	0.3	2.7	12.3	0.7	1.0	1.9	1.9	1.7	3.5	1.9	0.8	1.2	1.3	0.6	1.6	0.7	1.2	1.5	1.8	1.2	2.8
Blood White Count	0.3	2.2	7.8	1.5	1.8	-0.2	0.6	1.0	-1.4	2.2	1.7	2.0	1.1	1.3	2.8	2.2	1.2	0.9	1.6	0.1	-0.9
Height	0.3	5.8	30.4	2.1	0.1	1.9	1.5	3.6	5.5	2.0	0.6	0.6	1.7	1.5	-2.8	-0.8	0.8	2.8	3.2	3.2	2.9
Systolic Blood Pressure	0.3	1.4	9.2	1.1	0.8	-2.9	-0.3	0.4	-1.0	0.2	-0.1	0.6	-1.7	0.1	1.3	1.1	-0.0	-0.7	0.3	0.2	-3.0
Allergy or Eczema	0.3	0.8	5.3	-1.9	-0.4	2.3	0.7	-0.6	-0.2	-0.3	-0.1	0.0	1.2	-0.2	-0.7	-0.2	0.1	-0.4	-0.3	-1.1	-1.5
Hypothyroidism (self reported)	0.3	0.7	3.3	1.3	-0.0	-1.4	-0.7	-0.9	0.4	-1.1	0.1	-0.8	-1.8	-0.1	-0.5	-0.4	-0.5	-0.0	-0.7	0.9	1.0
Sensitivity / hurt feelings	0.3	0.5	1.8	0.2	-1.2	-0.5	0.1	0.2	0.3	-0.2	-0.7	-0.8	0.7	-0.6	-0.8	-0.5	-1.0	-0.6	-0.8	-1.4	-0.7
Angina	0.3	0.4	2.0	-0.4	-0.2	-0.6	-0.6	-0.4	-0.8	-0.4	-0.4	-0.6	-0.1	0.2	0.1	0.4	-1.0	-0.7	-0.7	-1.0	-1.4
Supplements: Zinc	0.3	0.3	1.7	-1.0	-0.3	-1.2	-0.1	1.3	-0.6	0.1	-0.5	-0.3	-0.2	-0.2	0.1	-0.2	-0.7	-0.3	0.4	-0.1	-0.2
Medication: Co-codamol	0.3	0.3	1.7	-1.0	-0.3	-0.1	0.3	-0.3	-1.3	0.2	-0.6	-0.3	0.3	-0.5	0.6	0.3	-0.2	-0.2	-0.9	-0.4	1.0
Current tobacco smoking	0.3	0.4	3.0	1.7	0.5	-0.8	0.7	0.2	0.1	0.5	0.7	-0.2	0.7	0.5	1.0	0.8	0.3	0.3	0.1	0.6	0.5
Sitting height	0.3	2.4	11.8	-0.2	-0.0	0.2	0.3	1.6	3.4	1.1	0.2	0.5	0.7	1.4	-2.6	-0.6	0.3	1.7	1.9	2.5	2.5
Had menopause	0.3	0.4	0.8	-0.9	-0.5	-0.9	-0.6	-0.7	-0.8	-0.2	-0.7	-0.8	-0.5	-0.6	-0.1	-0.5	-0.9	-0.5	-0.5	-0.4	-0.1
Medication: Ramipril	0.3	0.4	1.5	0.5	0.4	-1.1	0.8	0.7	-0.1	0.5	0.4	0.4	0.1	0.5	0.7	0.9	0.2	0.3	-0.1	-1.2	-1.1
Neuroticism score	0.3	0.6	2.3	0.4	0.2	-0.5	0.7	1.5	1.1	1.3	0.5	0.7	0.6	0.9	-0.0	0.5	-0.2	0.6	1.4	-0.1	-0.8
Father’s age at death	0.3	0.4	1.9	-0.6	-0.4	-0.5	-0.5	-1.4	0.6	-0.3	-0.3	0.4	-0.7	-1.0	0.1	-1.1	0.2	-0.2	0.9	0.4	0.4
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	5.7	-2.4	-1.1	0.2	-0.8	0.0	1.2	-0.2	-1.2	-0.6	0.9	-0.5	-2.3	-1.5	-1.0	-0.4	0.4	-0.5	-0.5
Prospective memory result	0.3	0.4	2.5	0.7	0.1	-0.8	0.4	1.6	0.6	0.6	-0.3	0.2	0.4	0.2	0.3	0.5	0.5	0.1	0.3	-0.6	1.3
Hair/balding pattern: Pattern 4	0.3	0.7	7.2	1.2	-0.1	-2.7	-1.3	1.1	-0.4	0.4	0.1	-0.1	0.1	0.1	0.3	-0.0	-0.8	-0.5	0.5	-0.9	-0.4
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.9	0.7	-0.0	0.0	0.2	-0.1	1.1	-0.4	-0.3	-0.3	-1.4	-0.4	0.2	-0.3	0.1	-0.2	0.3	0.1	1.3
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.5	-1.2	-0.1	-0.2	0.4	-1.0	-1.0	0.0	-0.5	-0.1	-0.0	-0.6	0.9	0.4	-0.3	-0.3	-0.8	-0.7	-0.9
Blood clot in the leg (DVT)	0.3	0.3	4.8	0.6	-0.2	0.1	0.0	0.3	0.5	-0.2	-0.1	-0.0	0.2	0.3	-0.6	-0.1	0.3	0.2	-0.0	-0.3	2.2
Medication: Amlodipine	0.3	0.4	2.1	-0.0	-0.3	-0.7	-0.2	0.1	-0.9	-0.4	-0.7	-0.4	-1.5	-0.4	0.0	0.0	-0.2	-0.7	-0.3	-1.2	0.7
Medication: Ventolin 100micrograms inhaler	0.3	0.4	4.3	-0.3	0.1	2.1	1.3	0.4	0.2	0.2	0.3	0.2	-0.0	0.1	0.4	0.5	0.6	0.3	-0.5	-0.2	-0.7
Angina (self-reported)	0.3	0.3	2.7	-0.3	0.0	-0.5	-0.4	-0.5	-0.7	-0.2	-0.2	-0.3	0.0	0.3	0.4	0.6	-0.7	-0.5	-0.5	-0.9	-1.6
Pulse rate, automated reading	0.3	1.0	2.5	-0.8	-1.1	-0.1	-0.6	-1.3	-1.4	-1.0	-1.6	-0.9	0.0	-0.9	-0.3	-0.1	-0.8	-1.1	-1.5	-1.6	0.7
Comparative height size at age 10	0.3	1.4	5.4	1.7	0.6	-0.9	0.6	1.4	2.0	1.0	0.4	0.9	0.3	0.5	-0.2	0.1	1.0	1.6	0.9	2.1	2.3
Number of full sisters	0.3	0.3	1.0	-0.4	-0.5	-0.5	-0.2	-1.0	-0.0	-0.5	-0.6	-0.4	-0.1	-0.8	0.2	-0.2	-0.5	-0.5	-0.6	-1.0	-0.9
Suffer from ‘nerves’	0.3	0.5	3.1	1.3	0.6	-0.1	0.2	1.5	0.7	0.6	0.7	0.5	-0.3	0.5	0.1	-0.1	0.4	0.0	1.8	0.7	-0.5
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.5	0.6	-0.1	-1.1	-0.1	-0.4	-0.1	-0.1	-0.0	0.0	0.0	0.2	0.0	0.5	-0.4	-0.1	-0.5	-1.2	-1.1
Illnesses of father: Heart disease	0.3	0.5	2.7	-0.1	0.4	-0.2	0.3	-1.5	-1.2	-0.0	0.4	0.1	-0.4	0.2	0.9	0.6	0.2	-0.0	-0.3	-0.9	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	2.2	1.5	-0.6	-1.1	-0.2	-0.1	1.0	-0.5	0.1	-0.7	0.0	-0.2	-1.4	-1.2	-0.7	-0.0	0.0	0.9	0.5
Loneliness, isolation	0.3	0.4	2.3	-0.5	0.5	1.5	0.9	0.3	-0.3	0.8	0.8	0.5	0.5	0.5	0.8	0.6	0.3	0.7	0.3	-0.5	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	3.1	-0.6	0.4	-0.1	0.3	-0.2	0.0	0.5	0.2	0.4	-0.5	0.5	0.3	0.4	-0.1	0.1	0.9	-0.2	-1.8
Osteoarthritis (self-reported)	0.3	0.3	2.2	0.9	-0.1	-0.7	0.6	0.5	-1.1	0.5	-0.2	-0.1	0.4	-0.8	1.5	0.1	0.2	-0.4	0.1	-0.1	-0.2
Number of self-reported non-cancer illnesses	0.3	0.6	1.6	-0.1	0.8	1.2	1.3	0.8	-0.3	0.5	0.5	0.4	0.7	0.6	1.2	1.1	1.1	0.4	0.2	-0.0	0.5
Average weekly champagne plus white wine intake	0.3	0.5	3.4	-1.2	-0.4	-0.9	-0.8	-0.8	-0.1	-0.3	-0.5	0.1	-0.5	-0.4	-0.6	-0.5	0.0	0.0	-0.4	-0.1	1.9
Guilty feelings	0.3	0.5	2.3	-1.4	-0.4	-1.5	-0.2	-0.7	-0.6	0.1	-0.7	0.2	-0.8	-0.6	-0.1	-0.4	-0.6	-0.4	-0.1	-0.2	-1.3
Ever taken oral contraceptive pill	0.3	0.4	1.8	0.3	-0.0	-0.3	-0.5	1.0	-1.0	0.4	-0.2	-0.0	0.7	0.4	-0.2	0.1	-0.3	-0.3	0.1	-1.2	-1.4
Basal cell carcinoma (self-reported)	0.3	0.4	1.1	-0.8	-0.9	0.8	0.0	0.1	-0.5	-0.4	-0.8	-1.1	0.4	-0.4	-0.7	-0.4	-1.0	-0.8	-0.4	-0.9	-0.3
Pack years of smoking	0.3	0.5	2.8	1.7	0.5	-0.9	0.6	0.4	0.1	0.7	0.6	0.1	0.1	0.3	1.7	1.0	0.2	0.2	-0.0	-0.0	-0.6
Alzheimer’s Disease (including proxy)	0.2	0.3	1.3	0.2	0.2	0.3	0.8	1.0	0.4	0.5	0.0	0.3	0.7	-0.7	1.1	0.1	1.0	-0.1	0.2	-0.2	0.5
Ulcerative Colitis (UC)	0.2	0.3	2.8	-0.6	0.0	0.4	0.8	1.1	-0.3	-0.0	0.0	-0.3	0.3	0.0	0.0	0.0	0.2	-0.4	0.8	0.3	-1.7
Reaction Time	0.2	0.4	2.2	-0.1	0.1	1.5	0.5	-1.0	-1.2	-0.6	0.4	-0.2	1.1	0.2	-0.1	0.0	0.7	0.2	-0.4	-0.3	1.0
Blood Platelet Count	0.2	2.1	10.0	3.0	1.8	-0.3	-0.3	-0.2	-3.2	0.5	1.7	0.8	-0.5	1.6	1.6	1.8	1.2	0.1	0.7	-1.1	-1.1
Blood Red Count	0.2	1.9	6.3	-0.2	-2.1	-1.2	-1.9	-0.0	-1.4	-0.9	-2.4	-0.9	0.4	-1.6	-1.0	-0.6	-1.9	-1.4	-1.5	-2.5	-0.0
Waist Hip Ratio (WHR)	0.2	0.7	3.5	1.9	0.8	-0.3	0.3	0.2	0.7	0.4	1.3	0.3	-0.1	0.4	0.5	0.2	0.8	0.5	0.9	0.9	-1.8
Neuroticism	0.2	0.5	1.1	-0.6	0.6	0.4	1.0	-0.1	0.9	1.0	0.7	1.0	0.8	1.0	0.5	1.0	0.4	1.0	0.8	-0.0	-0.3
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.9	0.4	-0.4	0.3	-0.3	0.2	-0.6	-0.2	-0.1	-1.4	-0.3	0.1	0.0	-0.1	-1.1	-0.7	-0.1	-0.9	0.2
Medication: Levothyroxine sodium	0.2	0.3	1.5	0.8	0.1	-1.2	-0.1	-0.5	1.1	-0.2	0.1	-0.2	-0.6	0.5	0.2	0.5	-0.6	0.3	-0.1	0.5	0.7
Alcohol usually taken with meals	0.2	0.4	1.3	-0.8	0.2	0.7	-0.6	0.9	0.7	0.0	0.5	-0.1	-0.4	0.5	-0.9	-0.6	0.2	-0.1	0.8	0.7	-1.1
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.6	-0.0	0.1	-0.5	0.5	0.1	1.0	0.2	-0.3	0.4	-0.9	-0.7	1.3	0.1	0.2	-0.1	-0.1	0.3	0.4
Falls in the last year	0.2	0.3	2.5	0.6	0.1	-1.6	-0.2	-0.9	-0.9	-0.1	0.0	0.1	-0.6	-0.0	0.6	0.1	-0.3	-0.2	0.3	0.0	-0.7
Depression (self-reported)	0.2	0.2	1.1	1.0	-0.4	-0.3	-0.6	0.2	0.5	0.0	-0.3	-0.6	0.3	0.2	-0.3	-0.1	-1.1	-0.6	0.3	-0.3	0.5
Medication: Lansoprazole	0.2	0.3	1.6	1.3	-0.3	-0.4	-0.2	0.4	-0.1	0.2	-0.1	0.1	-0.1	-0.6	0.7	-0.1	-0.5	-0.3	0.1	-0.8	1.1
Lung cancer (father)	0.2	0.2	1.3	1.1	0.0	-0.3	-0.1	0.4	0.4	0.1	0.1	-0.3	1.0	-0.1	0.6	0.2	-0.6	-0.2	-0.2	0.1	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.4	0.7	-0.4	0.6	0.7	0.4	1.2	0.1	-0.2	-0.7	-0.7	-0.6	0.3	-0.4	-0.4	-0.3	-0.1	-0.0	0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	1.6	0.7	-0.2	-0.9	-0.1	-0.6	1.0	-0.4	-0.0	-0.5	-1.3	0.1	-0.2	0.1	-0.5	0.1	-0.3	0.6	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.8	1.3	-0.2	-0.7	-0.4	0.7	-0.2	0.1	-0.2	-0.8	0.9	-0.1	-0.2	-0.1	-0.4	-0.2	-0.4	0.3	-0.2
Age at last live birth	0.2	0.3	1.3	-0.5	0.3	-0.4	0.2	-0.8	-0.3	-0.4	0.6	-0.1	-0.8	0.1	-0.5	-0.4	0.9	0.1	0.1	1.1	-1.1
Mood swings	0.2	0.4	2.7	0.1	-1.0	-0.1	-0.8	-0.3	-0.1	-0.7	-0.5	-0.8	-0.5	-0.2	-1.7	-0.9	-0.7	-0.7	-0.2	-0.4	0.4
Ever depressed for a whole week	0.2	0.2	1.0	0.0	0.1	0.1	0.4	-0.0	0.4	0.2	-0.0	-0.1	-1.0	-0.3	0.7	-0.1	0.2	0.1	-0.1	0.8	0.9
Supplements: Calcium	0.2	0.3	1.2	-1.1	0.4	0.1	0.7	1.1	-0.2	0.7	0.2	0.3	0.2	0.4	0.3	0.4	0.5	0.3	0.7	-0.1	0.1
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	4.4	0.4	-0.3	0.3	0.2	0.0	0.5	-0.3	-0.3	-0.0	-0.0	-0.0	-0.4	-0.2	0.3	0.0	-0.1	-0.4	2.1
Bipolar Disorder (2018)	0.1	0.2	1.6	-1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.2
Depressed Affect (Nagel 2018)	0.1	0.2	1.8	-1.3	-0.0	0.9	0.2	-0.5	0.2	-0.0	0.2	0.4	0.3	0.1	-0.6	-0.3	0.2	0.2	0.0	-0.3	-0.4
Neuroticism (Nagel 2018)	0.1	0.2	1.0	-0.8	0.1	-0.3	0.2	0.3	1.0	0.4	0.3	0.3	-0.1	0.4	-0.4	-0.1	-0.1	0.4	0.4	-0.1	-0.3
Primary Biliary Cirrhosis	0.1	0.2	1.1	-0.9	0.0	1.0	0.0	0.7	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0
Hair Pigment	0.1	1.5	7.7	-1.2	-0.1	2.8	2.3	1.1	1.4	1.6	0.3	0.6	1.8	0.4	1.1	1.0	-0.2	0.3	0.7	-1.2	-0.9
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.8	0.8	-0.1	-0.6	-0.1	0.3	0.6	0.1	0.1	-0.0	-0.4	-0.2	0.1	-0.2	-0.6	-0.2	0.2	0.0	-0.9
Taking other prescription medications	0.1	0.2	1.3	-0.1	-0.0	0.2	0.5	0.4	0.4	0.7	-0.1	-0.0	1.1	0.5	0.5	0.7	-0.1	0.3	-0.0	0.2	-0.3
Alcohol intake versus 10 years previously	0.1	0.2	0.7	0.3	0.4	-0.5	0.2	-0.3	-0.8	0.3	0.1	0.5	0.5	-0.2	0.9	0.4	0.3	-0.0	0.3	0.0	-0.5
Asthma	0.1	0.3	1.7	-1.0	0.0	1.3	1.0	0.4	0.0	0.1	0.2	0.0	0.4	-0.4	0.2	0.1	0.4	-0.0	-0.7	-0.2	-0.6
Gout (self-reported)	0.1	0.2	1.6	0.9	-0.3	0.3	0.4	0.3	0.3	-0.4	-0.2	-0.3	0.2	0.0	-1.3	-0.4	0.0	0.1	-0.0	0.2	0.3
Mean time to correctly identify matches	0.1	0.3	1.4	0.4	0.3	1.2	0.3	-0.2	-0.9	-0.4	0.4	-0.0	0.7	0.3	-0.1	0.2	0.8	0.3	-0.3	0.1	1.0
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.7	-0.3	-0.3	0.7	-0.2	-0.2	0.1	0.1	-0.3	-0.2	-0.4	-0.2	-0.1	-0.1	-0.7	-0.3	0.2	-0.9	-0.7
Back pain experienced in last month	0.1	0.2	2.7	-0.2	0.1	-0.4	0.3	-0.2	-0.0	0.3	-0.2	0.3	1.6	-0.3	0.7	0.1	-0.0	-0.1	0.3	0.2	-0.3
Asthma (self-reported)	0.1	0.3	1.1	-1.0	0.2	1.0	1.1	0.5	-0.0	0.4	0.3	0.2	0.5	-0.2	0.4	0.2	0.6	0.1	-0.3	-0.0	-0.5
Wears glasses or contact lenses	0.1	0.1	1.4	-0.0	-0.1	-1.2	0.2	-0.4	-0.5	0.1	-0.1	-0.0	0.5	0.2	-0.1	0.4	-0.1	0.2	-0.3	-0.1	0.4
Fractured/broken bones in last 5 years	0.1	0.1	0.3	0.3	0.3	0.6	0.4	-0.5	-0.0	-0.0	0.6	-0.2	0.3	0.3	-0.2	-0.2	0.1	-0.1	0.2	-0.2	-0.4
Diastolic blood pressure, automated reading	0.1	0.2	1.0	-0.0	0.3	0.4	0.3	-1.0	0.2	0.1	0.3	-0.3	-0.2	0.8	0.0	0.4	-0.6	-0.1	1.0	-0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.1	0.9	-1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.8
Schizophrenia (2018)	0.0	0.0	0.2	-0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.1	0.7	-0.2	0.0	-0.1	0.0	0.8	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.2
HbA1C	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.1	-0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tanning	0.0	0.6	2.6	0.6	0.7	0.5	0.6	0.5	0.6	0.7	0.7	1.4	0.6	0.4	0.7	0.6	0.9	0.2	0.9	-0.2	-1.6

Hub : Genes

SLC35E2B

Models

Trait associations