Best TWAS P=1.37e-08 · Best GWAS P=1.67e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | WNT2B | 0.29 | 0.28 | lasso | 3 | 0.29 | 2.6e-08 | -5.2 | -5.5 | 5.1e-08 | 0.94 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Pituitary | ST7L | 0.31 | 0.18 | lasso | 7 | 0.18 | 3.0e-05 | -4.6 | -5.5 | 4.9e-08 | 0.89 | 0.01 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | MOV10 | 0.06 | 0.06 | lasso | 7 | 0.05 | 9.4e-06 | -5.6 | -5.7 | 1.4e-08 | 0.97 | 0.00 | 0.99 | TRUE |