Best TWAS P=6.3e-10 · Best GWAS P=1.98e-07 conditioned to 0.501
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | TSPAN2 | 0.66 | 0.48 | lasso | 20 | 0.55 | 3.0e-19 | -4.5 | -5.2 | 2.6e-07 | 0.93 | 0.06 | 0.92 | FALSE |
| 2 | NTR | Blood | TSPAN2 | 0.03 | 0.01 | bslmm | 494 | 0.02 | 9.6e-07 | -5.2 | -5.6 | 1.9e-08 | 0.69 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | SIKE1 | 0.44 | 0.09 | lasso | 7 | 0.13 | 1.9e-04 | -4.5 | -6.2 | 6.3e-10 | 0.77 | 0.00 | 0.28 | TRUE |