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chr17:41,555,474-42,998,534

Best TWAS P=4.94e-10 · Best GWAS P=9.07e-10 conditioned to 0.194

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	ASB16-AS1	0.14	0.12	lasso	5	0.10	9.8e-06	5.4	-5.4	5.8e-08	-0.88	0.12	0.87	FALSE
2	GTEx	Breast Mammary Tissue (Female)	ASB16-AS1	0.08	0.04	lasso	2	0.06	7.9e-03	5.4	-5.4	7.4e-08	-0.87	0.06	0.50	FALSE
3	GTEx	Cells Transformed fibroblasts	ASB16	0.14	0.14	lasso	3	0.12	2.0e-09	5.5	-5.5	3.4e-08	-0.82	0.09	0.91	FALSE
4	GTEx	Cells Transformed fibroblasts	ASB16-AS1	0.17	0.17	lasso	4	0.16	2.3e-12	5.5	-5.3	1.1e-07	-0.77	0.09	0.91	FALSE
5	GTEx	Esophagus Mucosa	ASB16	0.10	0.10	lasso	4	0.08	8.2e-06	5.5	-5.5	3.7e-08	-0.82	0.10	0.89	FALSE
6	GTEx	Heart Left Ventricle	RP5-882C2.2	0.14	0.08	lasso	5	0.10	8.1e-06	5.3	-5.5	4.7e-08	-0.78	0.07	0.91	FALSE
7	GTEx	Nerve Tibial	ASB16	0.12	0.07	lasso	5	0.07	7.5e-06	5.5	-5.4	5.7e-08	-0.85	0.09	0.91	FALSE
8	GTEx	Nerve Tibial	ASB16-AS1	0.17	0.15	lasso	5	0.16	1.4e-11	5.5	-5.2	1.9e-07	-0.79	0.10	0.90	FALSE
9	GTEx	Skin Sun Exposed Lower leg	ASB16-AS1	0.13	0.09	lasso	5	0.07	2.7e-06	5.2	-5.2	2.3e-07	-0.80	0.13	0.87	FALSE
10	GTEx	Testis	ASB16-AS1	0.35	0.25	lasso	5	0.23	1.0e-10	5.5	-5.6	2.1e-08	-0.82	0.08	0.92	FALSE
11	GTEx	Thyroid	RP5-882C2.2	0.10	0.07	lasso	3	0.07	2.9e-06	5.5	-5.4	7.8e-08	-0.80	0.05	0.94	FALSE
12	GTEx	Thyroid	ASB16-AS1	0.14	0.06	lasso	2	0.04	5.4e-04	5.5	-5.5	3.0e-08	-0.82	0.09	0.84	FALSE
13	GTEx	Whole Blood	ASB16-AS1	0.14	0.05	lasso	6	0.04	3.1e-04	5.5	-5.6	2.1e-08	-0.83	0.11	0.89	FALSE
14	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C17orf65	0.03	0.00	blup	37	0.01	2.3e-02	5.5	-6.2	4.9e-10	-0.89	0.03	0.79	TRUE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	ASB16	0.05	0.06	blup	40	0.05	4.6e-04	5.3	-5.5	3.3e-08	-0.85	0.07	0.80	FALSE
16	The Cancer Genome Atlas	Colon Adenocarcinoma	C17orf65	0.05	0.06	blup	38	0.05	4.2e-04	4.1	-5.6	1.7e-08	-0.86	0.09	0.80	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ASB16	0.02	0.02	blup	39	0.02	3.8e-03	5.9	-6.2	7.3e-10	-0.86	0.02	0.50	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C17orf65	0.03	0.01	lasso	10	0.02	3.6e-03	5.9	-5.9	3.4e-09	-0.81	0.02	0.89	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ASB16	0.02	0.03	blup	40	0.03	1.3e-04	5.2	-5.8	6.3e-09	-0.89	0.11	0.87	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	ASB16	0.03	0.03	lasso	3	0.03	3.2e-04	5.4	-5.4	7.8e-08	-0.88	0.09	0.83	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	C17orf65	0.04	0.04	blup	37	0.03	1.4e-04	5.5	-5.3	1.1e-07	-0.83	0.11	0.87	FALSE
22	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ASB16	0.04	0.04	lasso	4	0.03	1.8e-04	5.9	-5.9	4.5e-09	-0.87	0.03	0.95	FALSE
23	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C17orf65	0.07	0.05	lasso	6	0.05	3.1e-06	5.5	-5.2	2.1e-07	-0.73	0.06	0.94	FALSE
24	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C17orf65	0.04	0.03	blup	39	0.03	2.7e-03	5.9	-5.3	9.2e-08	-0.87	0.03	0.80	FALSE
25	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C17orf65	0.09	0.09	enet	8	0.08	2.9e-04	5.2	-5.7	1.5e-08	-0.88	0.04	0.89	FALSE
26	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C17orf65	0.07	0.02	blup	38	0.04	1.1e-02	5.4	-6.1	1.4e-09	-0.89	0.02	0.35	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf65	0.03	0.03	lasso	7	0.03	3.8e-04	5.5	-5.8	8.9e-09	-0.86	0.05	0.87	FALSE