Best TWAS P=3.96e-08 · Best GWAS P=5.41e-07 conditioned to 0.0555
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Not Sun Exposed Suprapubic | EDEM3 | 0.14 | 0.07 | lasso | 7 | 0.08 | 4.6e-05 | 5.0 | -5.2 | 1.7e-07 | -0.89 | 0.02 | 0.98 | FALSE |
2 | GTEx | Uterus | EDEM3 | 0.27 | 0.02 | enet | 20 | 0.13 | 1.6e-03 | -3.7 | -5.5 | 4.0e-08 | -0.65 | 0.04 | 0.52 | TRUE |