Best TWAS P=7.37e-08 · Best GWAS P=1.09e-45 conditioned to 1.17e-39
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | AC092159.2 | 0.38 | 0.24 | lasso | 5 | 0.30 | 5.6e-24 | 4.8 | 5.3 | 1.0e-07 | -0.19 | 1 | 0 | FALSE |
| 2 | GTEx | Esophagus Muscularis | TMEM18 | 0.37 | 0.20 | lasso | 8 | 0.18 | 2.0e-11 | 4.8 | 5.2 | 1.6e-07 | -0.28 | 1 | 0 | FALSE |
| 3 | GTEx | Esophagus Muscularis | AC092159.2 | 0.26 | 0.16 | enet | 7 | 0.20 | 5.3e-12 | 4.8 | 5.4 | 7.4e-08 | -0.30 | 1 | 0 | TRUE |