Best TWAS P=1.34e-07 · Best GWAS P=1.74e-08 conditioned to 0.00337
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | TMEM165 | 0.09 | 0.01 | lasso | 3 | 0.03 | 1.6e-03 | 4.9 | -5.2 | 2.3e-07 | -0.76 | 0.10 | 0.89 | FALSE |
| 2 | GTEx | Colon Sigmoid | SRD5A3-AS1 | 0.16 | 0.14 | enet | 18 | 0.13 | 2.9e-05 | 4.9 | 5.3 | 1.3e-07 | 0.64 | 0.08 | 0.81 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TMEM165 | 0.02 | 0.04 | lasso | 3 | 0.03 | 1.0e-07 | 4.9 | -5.2 | 2.1e-07 | -0.77 | 0.04 | 0.95 | FALSE |