Best TWAS P=8.15e-10 · Best GWAS P=6.96e-10 conditioned to 7.13e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CENPC | 0.22 | 0.04 | enet | 17 | 0.10 | 2.8e-08 | 3.8 | -6.1 | 8.1e-10 | -0.22 | 0.71 | 0.20 | TRUE |
| 2 | GTEx | Esophagus Mucosa | CENPC | 0.13 | 0.03 | enet | 8 | 0.08 | 3.6e-06 | 3.8 | -5.4 | 7.2e-08 | -0.07 | 0.62 | 0.25 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | CENPC | 0.18 | 0.14 | enet | 19 | 0.15 | 3.6e-12 | 4.5 | -5.4 | 7.7e-08 | -0.13 | 0.58 | 0.40 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CENPC1 | 0.24 | 0.07 | enet | 3 | 0.06 | 2.8e-07 | 4.5 | -5.5 | 4.3e-08 | -0.09 | 0.07 | 0.89 | FALSE |