[Hub]/) : Traits : Leg fat mass (right) :

chr5:76,597,461-78,287,579

Best TWAS P=4.37e-12 · Best GWAS P=4.49e-11 conditioned to 0.0852

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 METSIM Adipose AP3B1 0.07 0.01 blup 556 0.02 2.4e-04 2.9 -5.2 1.8e-07 0.53 0.10 0.78 FALSE
2 YFS Blood AP3B1 0.25 0.22 lasso 9 0.23 2.6e-74 5.4 -5.7 1.5e-08 0.31 0.81 0.19 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma AP3B1 0.02 0.00 blup 126 0.01 1.8e-02 -6.4 -6.7 2.6e-11 0.86 0.02 0.90 FALSE
4 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma AP3B1 0.16 0.06 enet 18 0.09 2.2e-05 5.8 -5.4 6.1e-08 0.53 0.04 0.56 FALSE
5 The Cancer Genome Atlas Prostate Adenocarcinoma AP3B1 0.05 0.02 blup 126 0.03 5.0e-04 5.7 -6.9 4.4e-12 0.80 0.02 0.91 TRUE
6 The Cancer Genome Atlas Thyroid Carcinoma AP3B1 0.11 0.06 lasso 2 0.05 1.3e-05 5.4 -5.2 2.3e-07 0.20 0.50 0.19 FALSE