TWAS hub - AP3B1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0770	0.0230	4.6e-05	0.058	0.036	0.024	0.038	0.046	1.2e-07	2.8e-05	5.7e-04	1.8e-05	2.3e-06
2	METSIM	Adipose	0.0659	0.0245	3.1e-04	0.005	0.022	0.018	0.018	0.011	4.5e-02	2.4e-04	9.5e-04	7.7e-04	8.3e-03
3	YFS	Blood	0.2524	0.0316	0.0e+00	0.222	0.192	0.225	0.226	0.231	6.1e-71	1.2e-60	4.0e-72	2.6e-72	2.6e-74
4	TCGA	Breast Invasive Carcinoma	0.0194	0.0110	3.9e-03	0.000	0.006	-0.001	NA	-0.001	3.9e-01	1.8e-02	5.2e-01	NA	4.4e-01
5	TCGA	Cervical Squamous Cell Carcinoma	0.1610	0.0750	2.2e-03	0.056	0.068	0.095	NA	0.056	9.3e-04	2.9e-04	2.2e-05	NA	1.0e-03
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0829	0.0406	3.2e-03	0.014	0.017	0.024	NA	0.020	9.8e-03	4.7e-03	9.7e-04	NA	2.3e-03
7	TCGA	Brain Lower Grade Glioma	0.0539	0.0314	7.1e-03	0.005	0.007	0.017	NA	0.005	8.3e-02	4.2e-02	4.1e-03	NA	7.4e-02
8	TCGA	Lung Adenocarcinoma	0.0478	0.0238	1.1e-03	0.035	0.031	0.033	NA	0.036	5.5e-05	1.3e-04	9.2e-05	NA	4.4e-05
9	TCGA	Prostate Adenocarcinoma	0.0466	0.0229	9.3e-04	0.016	0.029	0.013	NA	0.020	6.9e-03	5.0e-04	1.5e-02	NA	3.2e-03
10	TCGA	Thyroid Carcinoma	0.1080	0.0540	5.5e-04	0.063	0.031	0.030	NA	0.050	8.6e-07	5.0e-04	6.1e-04	NA	1.2e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Weight	9.4	46.3	89.7	-1.4	-6.6	-7.1	-9.5	-7.5	-7.0	-1.1	-6.7	-9.3	-6.4
Leg fat-free mass (left)	9.0	47.6	100.0	-1.1	-7.2	-6.8	-10.0	-7.2	-7.1	-0.7	-6.8	-9.6	-6.0
Leg predicted mass (left)	8.9	47.2	100.0	-1.0	-7.2	-6.7	-10.0	-7.2	-7.1	-0.6	-6.8	-9.6	-5.9
Basal metabolic rate	8.3	45.8	95.5	-0.9	-6.9	-6.6	-9.8	-7.3	-6.8	-0.8	-6.8	-9.3	-6.0
Hip circumference	8.1	34.8	65.0	-1.1	-5.7	-6.3	-8.0	-6.5	-6.2	-1.2	-5.7	-8.1	-5.7
Whole body fat-free mass	7.8	44.5	95.3	-0.6	-6.8	-6.4	-9.8	-7.2	-6.8	-0.6	-6.6	-9.3	-5.8
Forced vital capacity (FVC)	7.6	29.1	83.8	3.2	-4.9	-3.1	-9.2	-5.2	-6.4	1.7	-4.4	-8.3	-2.0
Leg fat-free mass (right)	7.6	40.4	87.6	-0.7	-6.4	-6.1	-9.4	-6.8	-6.6	-0.4	-6.1	-8.9	-5.5
Whole body water mass	7.6	43.5	93.1	-0.7	-6.7	-6.3	-9.7	-7.2	-6.6	-0.6	-6.6	-9.2	-5.7
Trunk fat mass	7.5	32.2	63.5	-1.4	-5.2	-6.1	-7.9	-6.2	-5.8	-0.7	-5.3	-8.0	-5.4
Leg predicted mass (right)	7.4	39.5	85.6	-0.7	-6.4	-6.0	-9.2	-6.7	-6.5	-0.5	-6.0	-8.8	-5.5
Arm fat mass (right)	7.2	29.6	55.1	-1.8	-4.8	-6.0	-7.1	-6.1	-5.3	-1.4	-5.3	-7.4	-5.6
Whole body fat mass	7.2	30.2	58.6	-1.5	-5.2	-6.0	-7.5	-6.0	-5.4	-0.9	-5.2	-7.7	-5.3
Arm fat-free mass (right)	7.0	35.7	85.0	-0.1	-6.3	-5.3	-9.2	-6.8	-5.6	0.4	-5.7	-8.5	-4.6
Arm fat mass (left)	7.0	28.6	54.0	-1.7	-4.9	-5.9	-7.2	-5.9	-5.2	-1.3	-5.2	-7.3	-5.4
Trunk fat-free mass	6.9	39.8	84.2	-0.6	-6.2	-6.0	-9.2	-7.0	-6.4	-0.8	-6.5	-8.7	-5.5
Trunk predicted mass	6.9	39.2	83.2	-0.6	-6.2	-6.0	-9.1	-7.0	-6.3	-0.7	-6.4	-8.6	-5.5
Forced vital capacity (FVC), Best measure	6.9	25.1	71.7	3.2	-4.6	-3.2	-8.5	-5.3	-5.6	1.0	-3.7	-7.7	-2.1
Arm predicted mass (left)	6.8	34.7	78.0	-0.4	-6.2	-5.6	-8.8	-6.7	-5.5	-0.2	-5.8	-8.2	-4.9
Leg fat mass (right)	6.7	26.1	47.9	-1.7	-5.2	-5.7	-6.7	-5.4	-4.9	-1.2	-5.0	-6.9	-5.2
Arm predicted mass (right)	6.7	34.5	81.3	-0.3	-6.3	-5.3	-9.0	-6.6	-5.4	0.2	-5.6	-8.3	-4.7
Arm fat-free mass (left)	6.5	32.9	72.6	-0.3	-6.0	-5.5	-8.5	-6.6	-5.5	-0.2	-5.5	-7.9	-5.0
Sitting height	6.2	44.1	139.2	4.4	-6.1	-3.9	-11.8	-6.4	-7.2	3.5	-4.5	-10.0	-2.4
Leg fat mass (left)	6.1	23.8	44.4	-1.6	-4.8	-5.4	-6.4	-5.3	-4.6	-1.1	-4.6	-6.7	-5.0
Comparative height size at age 10	5.2	28.7	76.6	2.0	-3.9	-4.0	-8.8	-5.8	-6.3	1.4	-4.9	-8.2	-3.0
Waist circumference	5.0	18.3	31.0	-2.0	-3.6	-4.9	-5.3	-5.1	-3.8	-1.4	-4.1	-5.6	-4.8
Mouth/teeth dental problems: Dentures	5.0	8.5	13.5	-1.6	-2.7	-3.5	-1.9	-3.7	-2.7	-2.4	-3.4	-3.3	-3.3
Trunk fat percentage	4.9	19.6	38.1	-1.5	-4.1	-5.0	-5.9	-4.7	-4.5	-0.6	-4.0	-6.2	-4.4
Risk taking	4.7	6.8	10.6	-0.8	-1.7	-3.2	-2.6	-3.1	-3.3	-1.6	-2.5	-3.0	-3.0
Body mass index (BMI)	4.6	19.4	33.8	-2.0	-4.1	-4.9	-5.5	-4.7	-4.3	-1.3	-4.5	-5.8	-4.7
Forced expiratory volume in 1-second (FEV1)	4.6	15.7	46.4	2.7	-3.5	-2.2	-6.8	-3.6	-4.9	1.0	-3.1	-6.0	-1.5
Arm fat percentage (left)	4.6	18.3	33.3	-2.2	-3.8	-5.0	-5.3	-4.4	-4.1	-1.3	-4.2	-5.8	-4.6
Arm fat percentage (right)	4.5	17.9	31.4	-2.2	-3.6	-5.1	-5.0	-4.4	-4.2	-1.6	-4.2	-5.6	-4.7
Body fat percentage	4.4	17.3	32.1	-1.6	-3.9	-4.9	-5.4	-4.5	-4.0	-0.8	-3.9	-5.7	-4.3
Comparative body size at age 10	4.4	12.2	25.8	0.2	-3.2	-3.0	-5.1	-3.9	-4.5	-0.7	-3.1	-4.9	-2.7
Forced expiratory volume in 1-second (FEV1), Best measure	4.2	13.5	38.3	2.5	-3.4	-2.3	-6.2	-3.8	-4.2	0.5	-2.7	-5.5	-1.6
BMI	4.1	23.5	38.6	-2.2	-5.3	-5.3	-6.2	-5.5	-4.0	-1.3	-5.0	-6.1	-5.0
Standing height	3.7	36.9	88.4	1.2	-5.5	-5.4	-9.4	-6.8	-6.8	0.2	-5.6	-8.6	-4.6
Impedance of leg (left)	3.3	16.1	31.7	1.6	3.4	3.9	5.6	4.1	4.4	0.8	4.4	5.5	3.8
Number of self-reported non-cancer illnesses	3.3	5.8	9.6	-1.7	-1.7	-3.1	-3.0	-2.7	-2.3	-0.2	-2.1	-3.0	-2.7
Leg fat percentage (right)	3.1	11.4	17.1	-1.8	-3.8	-4.1	-3.7	-3.4	-2.8	-1.3	-3.5	-4.1	-3.8
Primary Biliary Cirrhosis	3.0	4.3	9.2	3.0	-0.2	2.8	0.0	1.6	1.1	2.8	2.0	1.0	3.0
Height	3.0	58.1	137.8	3.3	-6.2	-5.6	-11.7	-8.8	-9.6	0.7	-6.7	-11.2	-4.7
Lung FVC	3.0	15.3	41.4	3.7	-1.6	-1.7	-6.4	-4.3	-5.3	1.3	-2.4	-6.1	-0.8
Commuting to job workplace: Walk	3.0	3.2	11.2	-0.7	1.8	1.8	3.4	1.4	1.8	-0.8	0.9	2.5	1.1
Loud music exposure frequency	2.8	3.0	7.5	-1.1	-1.2	-1.7	-1.7	-2.7	-0.8	-0.6	-2.5	-2.1	-1.6
Overall health rating	2.8	5.9	10.5	-3.1	-2.0	-3.1	-1.3	-1.8	-2.3	-1.6	-2.7	-2.2	-3.2
Waist Hip Ratio (WHR)	2.6	11.6	28.5	-0.6	3.8	3.1	5.3	3.1	3.8	-0.3	3.4	4.7	2.2
Hypothyroidism/myxoedema (self-reported)	2.6	5.0	9.5	-2.2	-0.2	-2.6	-1.3	-3.0	-1.1	-2.5	-3.1	-1.8	-2.9
Shortness of breath walking on level ground	2.6	3.1	5.6	-0.4	-1.8	-1.5	-1.7	-2.1	-2.2	0.0	-2.1	-2.4	-1.8
Bipolar Disorder (2011)	2.4	2.4	5.2	2.2	-0.9	2.2	0.9	2.3	0.4	0.0	1.7	1.3	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.6	8.3	2.3	-1.5	0.0	-2.7	-1.4	-2.0	2.7	-0.4	-2.9	0.4
Leg fat percentage (left)	2.3	8.2	13.3	-1.5	-2.9	-3.6	-3.2	-3.0	-2.3	-1.1	-2.8	-3.6	-3.4
Hypothyroidism (self reported)	2.2	4.9	10.7	-1.3	-0.3	-2.6	-1.7	-3.3	-1.9	-2.0	-2.8	-2.1	-2.7
Frequency of depressed mood in last 2 weeks	2.2	3.1	8.8	-1.0	-3.0	-1.8	-1.6	-1.7	-1.4	-0.1	-1.8	-2.1	-1.7
Diabetes (mother)	2.2	2.8	5.7	-1.3	-1.8	-2.4	-1.2	-1.4	-1.4	-1.3	-1.6	-1.3	-2.3
Ever taken oral contraceptive pill	2.2	2.5	6.5	-0.6	0.7	1.6	2.5	2.1	1.5	0.1	0.9	2.3	1.5
Fractured/broken bones in last 5 years	2.2	2.9	6.4	-1.7	-1.3	-2.4	-0.3	-1.1	-2.3	-1.7	-1.6	-0.5	-2.5
Impedance of leg (right)	2.1	9.9	21.5	1.1	2.2	3.0	4.6	3.4	3.4	0.4	3.1	4.5	3.1
Long-standing illness, disability or infirmity	2.1	3.2	7.9	-0.7	-1.2	-2.4	-1.8	-0.8	-2.8	-1.0	-1.6	-2.3	-2.0
Other serious medical condition/disability diagnosed by doctor	2.0	2.6	4.8	-0.5	-1.5	-2.2	-1.7	-1.9	-1.4	-0.9	-1.4	-1.8	-2.0
Time employed in main current job	2.0	2.3	4.0	1.2	1.9	2.0	1.5	1.8	-0.4	0.6	1.7	1.4	1.8
Exposure to tobacco smoke outside home	2.0	2.6	6.2	0.0	-2.0	-1.4	-1.7	-1.6	-2.0	0.3	-1.7	-2.5	-1.3
Major Depression (MDD)	1.9	2.3	7.1	-0.5	-1.9	-1.3	-2.7	-1.0	-0.7	-0.2	-1.8	-2.2	-0.9
Sensitivity / hurt feelings	1.9	3.2	8.1	0.2	-1.9	-0.9	-2.5	-1.6	-2.0	1.2	-2.2	-2.9	-0.4
Past tobacco smoking	1.9	3.6	6.8	1.1	-0.4	2.6	1.6	2.1	2.6	1.3	1.5	1.8	2.5
Exposure to tobacco smoke at home	1.9	2.1	5.8	0.7	-2.4	-0.9	-2.0	-0.8	-1.6	0.2	-1.4	-2.1	-0.5
Medication: Paracetamol	1.9	3.2	10.7	-3.3	-1.7	-2.1	-0.5	-1.0	-0.5	-1.3	-2.3	-0.8	-2.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	10.1	3.2	0.5	1.4	-1.0	0.6	-0.4	2.3	1.3	-0.5	1.9
Smoking status: Previous	1.9	2.8	6.2	-1.2	0.8	-2.1	-1.3	-1.7	-2.5	-1.5	-1.4	-1.4	-2.1
Lupus	1.8	2.8	6.6	2.5	0.4	2.6	-0.0	0.2	0.7	2.5	1.0	0.3	2.6
Ever unenthusiastic/disinterested for a whole week	1.8	2.2	6.6	-0.6	-1.0	-0.7	-1.8	-1.7	-1.6	1.2	-1.7	-2.6	-0.3
Headache pain in last month	1.8	3.1	12.1	0.5	-2.4	-1.8	-3.5	-1.1	-0.7	0.4	-1.1	-2.3	-1.2
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	4.8	-1.2	-2.2	-1.6	-2.0	-1.4	-0.8	0.1	-1.9	-1.7	-1.2
Depression (Nagel 2018)	1.7	2.5	10.4	0.0	-3.2	-1.2	-2.0	-1.5	-0.8	0.1	-1.5	-1.7	-1.0
Noisy workplace	1.7	2.1	4.3	-1.4	-1.4	-2.1	-1.8	-1.2	-0.2	-0.5	-1.5	-1.5	-1.7
Hearing aid user	1.7	1.9	5.4	1.7	0.0	2.0	-0.2	0.6	0.8	2.3	0.8	0.3	2.3
Impedance of whole body	1.7	8.7	16.1	1.2	2.8	2.8	4.0	3.4	2.6	0.5	3.2	4.0	2.9
Allergy or Eczema	1.6	4.1	8.8	-2.4	-2.2	-3.0	-0.8	-0.6	-1.2	-2.2	-2.6	-0.7	-2.6
Blood clot in the leg (DVT)	1.6	2.1	4.0	-1.3	-1.9	-1.5	-2.0	-1.3	-0.7	0.1	-1.8	-1.6	-1.1
Gout (self-reported)	1.6	2.3	11.2	1.7	-0.7	1.1	-1.1	0.9	-0.1	3.4	1.4	-0.1	1.6
Age at last live birth	1.6	2.3	4.6	1.7	1.1	1.6	1.0	1.6	0.2	2.1	2.1	0.9	1.8
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.3	7.2	0.6	-2.7	-1.6	-2.6	-1.3	-2.5	0.1	-1.5	-2.4	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.3	9.0	2.0	-0.8	-1.1	-3.0	-1.6	-2.4	-0.3	-0.8	-2.9	-1.0
Age at First Birth	1.5	2.2	6.4	2.5	0.9	1.8	1.0	0.9	-0.1	0.0	2.3	0.7	2.0
Medication: Levothyroxine sodium	1.5	2.5	5.0	-1.2	0.4	-1.6	-0.8	-2.0	-1.1	-2.2	-2.2	-1.3	-1.9
Heart disease (mother)	1.5	1.9	5.5	0.9	-0.9	-1.5	-2.3	-1.7	-1.1	-0.4	-0.7	-1.6	-1.3
Ever had bowel cancer screening	1.5	1.8	4.4	1.0	-1.7	-1.3	-1.7	-1.0	-1.7	-0.0	-0.7	-2.1	-0.8
Medication: Paracetamol	1.5	2.3	6.6	-2.6	-1.3	-1.9	0.1	-0.5	-1.1	-1.5	-1.9	-0.4	-1.9
Bipolar Disorder (2018)	1.4	2.2	5.8	1.6	-0.1	2.4	0.1	1.9	0.6	1.4	1.3	0.4	2.4
Blood Platelet Count	1.4	16.3	56.2	4.5	7.5	5.2	2.6	2.0	-0.5	1.7	4.5	1.8	4.7
Mouth/teeth dental problems: Loose teeth	1.4	1.6	3.6	-1.1	-1.1	-1.6	-0.2	-1.4	-1.4	-1.2	-1.5	-0.5	-1.9
Medication: Allopurinol	1.4	1.9	7.9	2.0	-0.8	0.9	-1.1	0.6	-0.4	2.8	1.3	-0.7	1.3
Family relationship satisfaction	1.4	1.7	5.0	0.1	-1.0	-0.2	-1.8	-1.0	-2.2	1.2	-1.4	-1.9	0.0
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	4.9	-1.2	0.7	0.4	1.7	2.2	1.0	0.2	0.8	1.9	0.0
Bipolar Disorder or Schizophrenia	1.3	3.2	6.5	2.6	0.9	2.5	0.3	1.9	0.0	1.8	2.0	0.9	2.5
Taking other prescription medications	1.3	2.1	4.4	-1.3	-0.8	-1.7	-1.0	-1.1	-2.1	-1.0	-1.6	-1.7	-1.6
Mouth/teeth dental problems	1.3	2.0	5.5	0.7	0.4	2.3	-0.4	1.6	1.0	2.2	0.6	0.4	2.1
Pulse rate	1.3	2.1	8.2	1.7	-0.9	0.8	-2.4	0.4	0.2	2.9	0.4	-1.1	1.1
Qualifications: A levels/AS levels or equivalent	1.3	2.8	7.8	2.8	1.2	2.2	0.3	2.0	-0.1	1.3	1.7	1.0	2.2
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	3.9	0.1	-1.7	-0.9	-2.0	-1.1	-1.6	-0.0	-1.3	-1.3	-0.8
Illnesses of mother	1.3	1.6	3.9	0.4	0.8	1.5	1.0	1.1	1.3	1.3	1.4	1.3	2.0
Medication: Ibuprofen	1.3	1.5	4.4	0.4	0.9	1.6	2.1	0.9	1.4	-0.0	1.1	1.6	1.1
Leg pain on walking	1.3	1.7	3.6	0.8	-1.8	-0.9	-1.7	-0.8	-1.5	-0.2	-1.2	-1.9	-1.0
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	5.9	0.1	0.6	0.8	1.6	0.5	2.4	-0.3	1.7	1.6	0.8
Medication: Gliclazide	1.3	1.5	4.2	1.1	-1.0	-1.1	-2.0	-1.1	-1.3	0.3	-0.6	-1.6	-1.1
Medication: Lisinopril	1.3	1.7	4.9	0.0	-0.2	-1.2	-1.1	-1.7	-2.2	-0.5	-1.3	-1.7	-1.3
Heart disease (siblings)	1.3	1.6	4.6	1.0	-1.1	-0.8	-2.1	-1.7	-1.0	1.3	-0.9	-1.4	-0.5
Average weekly fortified wine intake	1.2	1.4	5.0	1.4	1.6	0.7	-0.7	0.8	-2.2	1.0	0.9	-0.4	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	3.0	-0.3	-1.7	-1.4	-1.3	-0.3	-1.6	-0.1	-0.9	-1.6	-1.1
Back pain experienced in last month	1.2	1.7	6.5	-0.8	-2.5	-1.1	-1.4	-1.2	-0.4	-0.1	-1.7	-1.4	-0.6
Ever depressed for a whole week	1.2	1.5	4.5	-0.3	-1.5	-0.7	-1.7	-0.9	-1.2	0.4	-1.2	-2.1	-0.6
Unable to work because of sickness or disability	1.2	1.6	5.7	-1.2	-1.4	-1.4	0.2	-0.3	-0.3	-2.4	-1.2	-0.3	-1.6
Number of treatments/medications taken	1.1	2.0	3.5	-0.8	-1.0	-1.7	-1.8	-1.9	-1.3	-0.0	-1.4	-1.7	-1.7
Ever had hysterectomy (womb removed)	1.1	1.2	4.3	1.4	0.2	1.4	-0.3	0.4	0.7	2.1	0.7	0.5	1.7
Pain all over the body in last month	1.1	1.2	4.4	-0.5	0.5	-1.0	0.3	0.8	-2.1	-1.4	-0.7	0.2	-1.5
Medication: Seretide 50 evohaler	1.1	1.2	2.4	-1.6	-0.6	-1.3	-0.4	-0.5	-0.5	-1.4	-1.4	-1.1	-1.4
Pulse rate, automated reading	1.1	3.4	14.2	0.9	-1.7	-1.0	-3.8	-1.0	-1.4	2.0	-1.2	-2.7	-0.5
Osteoarthritis (self-reported)	1.1	1.4	2.8	-0.4	-1.5	-1.6	-1.1	-1.3	-1.1	-0.6	-0.3	-1.4	-1.7
Neuroticism (Nagel 2018)	1.0	2.3	7.0	2.6	-0.6	1.5	-1.5	0.1	-0.5	2.6	0.2	-0.4	2.0
Type 2 Diabetes (T2D) (2012)	1.0	1.2	6.4	0.7	0.0	-0.2	-0.6	-0.5	-2.5	-0.7	-0.6	-1.8	-0.3
Smoking Status	1.0	2.5	4.8	-0.4	-0.4	-1.9	-2.2	-1.5	-2.0	-0.4	-1.2	-2.1	-2.0
Lung FEV1/FVC ratio	1.0	5.3	14.5	-2.1	2.9	1.2	3.8	2.3	2.0	-2.0	0.8	3.1	0.0
Neuroticism	1.0	2.3	6.0	2.3	-1.1	0.8	-2.1	0.6	-1.6	2.5	-0.3	-0.8	1.4
Tanning	1.0	12.1	21.8	-2.6	-3.9	-4.4	-1.6	-3.8	-2.6	-2.9	-4.4	-2.5	-4.7
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	3.0	-1.0	-1.2	-1.4	-0.9	-0.7	-0.5	-0.6	-1.7	-0.8	-1.3
Angina	1.0	1.4	4.2	1.0	2.1	0.2	0.8	1.0	-0.9	0.8	1.9	1.3	0.3
Vitamin and mineral supplements	1.0	1.4	5.5	-2.3	0.8	-0.7	0.6	-0.5	-0.5	-1.8	-1.2	0.1	-1.2
Allergy	1.0	2.2	5.2	2.2	1.0	2.1	1.1	0.0	1.0	1.0	2.3	0.9	1.8
Illnesses of siblings	1.0	1.4	2.9	0.1	1.3	0.7	1.0	1.4	1.7	0.5	1.4	1.5	1.2
Breastfed as a baby	1.0	1.3	3.7	0.9	0.5	1.7	0.4	1.2	-0.7	1.9	0.4	0.1	1.6
Tense / ‘highly strung’	1.0	1.7	3.7	0.0	-1.5	-1.0	-1.9	-1.6	-1.1	-0.3	-1.7	-1.7	-0.8
Glaucoma (self-reported)	1.0	1.2	3.2	-1.4	-0.4	-1.8	-0.7	-1.1	0.2	-0.9	-1.1	-0.7	-1.5
Medication: Amlodipine	1.0	1.4	3.5	-1.0	-0.8	-0.8	-1.8	-1.9	-0.9	0.2	-1.4	-1.4	-0.7
Birth weight	1.0	2.2	8.1	-0.1	-1.1	-1.5	-2.8	-0.6	-1.4	0.2	-1.9	-1.7	-1.1
Angina (self-reported)	1.0	1.3	4.0	1.0	2.0	0.3	0.8	1.1	-0.8	0.8	2.0	1.2	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.1	3.5	-1.6	0.0	-0.2	1.0	1.7	1.0	-0.5	0.5	1.9	-0.4
Had major operations	1.0	1.2	3.9	0.9	-0.7	-0.1	-2.0	-1.1	-0.5	1.5	-0.5	-1.6	0.2
Pain type(s) experienced in last month: Hip pain	1.0	1.3	4.2	2.0	0.0	1.1	-0.0	-0.7	0.5	1.3	1.7	0.4	1.4
Pain experienced in last month	1.0	1.6	3.9	-0.6	2.0	1.5	1.9	0.6	1.1	-0.8	1.0	1.4	0.9
Alzheimer’s Disease (including proxy)	0.9	1.3	3.2	1.8	0.6	1.2	0.3	1.3	0.8	1.5	0.9	0.9	1.4
HbA1C	0.9	1.0	3.0	1.7	0.0	0.1	-1.6	-0.7	-1.3	0.9	0.5	-0.9	0.2
HDL Cholesterol	0.9	1.5	3.3	0.8	1.8	1.5	1.0	1.2	0.5	1.1	1.4	1.1	1.5
Schizophrenia (2014)	0.9	1.9	3.6	1.1	1.9	1.2	1.3	1.7	-0.9	0.3	1.9	1.5	1.1
Relative age of first facial hair	0.9	1.9	4.8	0.0	1.4	1.8	1.1	2.2	0.5	1.3	1.3	1.2	1.7
Age when periods started (menarche)	0.9	2.1	6.0	-2.4	0.7	0.4	2.5	0.7	1.6	-1.6	0.1	1.7	0.1
Serious illness, injury or assault to yourself	0.9	1.1	2.4	-0.3	1.4	0.2	1.6	1.4	-0.1	-1.4	0.8	1.2	-0.2
Nervous feelings	0.9	1.6	2.8	1.6	1.0	1.4	0.7	1.3	0.4	1.5	1.5	1.0	1.7
Hair/balding pattern: Pattern 2	0.9	1.1	2.4	1.5	0.3	0.0	-1.5	-0.0	-1.5	1.6	-0.1	-1.3	0.0
Had menopause	0.9	1.2	3.3	1.0	-0.0	-0.9	-1.8	-1.2	-1.3	0.9	-0.2	-1.3	-0.9
Financial difficulties in last 2 years	0.9	1.2	2.8	-0.4	-1.4	-1.1	-0.6	-0.8	-1.7	0.5	-1.6	-1.1	-1.0
Length of working week for main job	0.9	1.0	3.5	1.4	0.1	0.4	-1.9	-0.6	-0.9	0.9	-0.3	-1.4	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	2.9	1.3	-0.4	-0.2	-1.7	-1.2	-1.2	0.1	-0.7	-1.6	-0.0
Age at first live birth	0.9	1.5	3.2	1.8	0.7	0.9	-0.2	1.8	-1.0	1.6	1.7	0.4	1.0
Supplements: Vitamin C	0.9	1.1	3.6	1.5	-0.1	0.5	-1.7	-0.2	-0.1	1.9	0.4	-1.0	0.9
Knee pain experienced in last month	0.9	1.4	8.8	0.1	-3.0	-0.9	-1.3	-0.0	-0.2	0.1	-0.8	-1.0	-0.9
Guilty feelings	0.9	1.3	2.8	1.1	-0.8	1.6	0.2	1.3	1.3	1.4	0.6	0.8	1.7
Eye problems/disorders: Glaucoma	0.9	1.1	3.8	-1.9	-0.1	-1.5	-0.2	-0.6	0.7	-0.9	-1.1	0.0	-1.2
Illnesses of father: High blood pressure	0.9	1.1	3.6	-0.2	-0.1	0.5	1.2	1.4	1.9	0.3	0.8	1.8	0.6
Age started oral contraceptive pill	0.9	1.1	3.9	1.4	1.0	1.0	-0.9	-0.1	0.6	2.0	0.7	0.1	1.3
Alzheimer’s Disease (in father)	0.8	0.8	2.0	1.3	-0.3	1.0	-0.1	1.4	-0.1	1.0	0.9	0.7	1.0
Blood Red Count	0.8	8.1	11.4	2.0	2.5	3.3	2.1	2.2	3.2	3.2	3.0	3.1	3.4
High blood pressure	0.8	2.2	3.6	-1.3	-1.5	-1.2	-1.1	-1.6	-1.9	0.1	-1.7	-1.9	-1.6
Medication: Atenolol	0.8	1.0	2.9	-0.0	-1.1	-0.6	-1.5	-1.0	-1.2	0.7	-0.7	-1.7	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	3.5	1.2	-1.9	-0.3	-0.9	-1.0	-1.5	0.1	-1.0	-1.3	-0.2
Medication: Simvastatin	0.8	1.2	7.6	-0.1	2.8	0.2	1.1	0.3	0.6	-0.2	1.1	1.3	0.1
Alcohol intake versus 10 years previously	0.8	1.2	6.4	0.6	-2.5	0.1	-1.7	-0.1	0.9	0.8	-0.3	-1.0	0.6
Worrier / anxious feelings	0.8	1.4	3.6	1.6	0.2	1.1	-1.5	0.5	-0.5	1.9	-0.1	-1.1	1.7
Falls in the last year	0.8	1.1	4.4	-0.5	0.6	-0.8	0.3	-0.4	-2.1	-1.6	-0.9	-1.0	-1.0
Number of live births	0.8	1.1	4.2	-1.2	-0.4	-0.4	1.2	-1.5	2.0	-0.8	-0.4	0.3	-0.5
Peak expiratory flow (PEF)	0.8	1.8	6.5	2.1	-0.6	0.5	-2.5	-0.1	-1.3	1.6	-0.2	-1.3	0.8
Pulse wave reflection index	0.8	1.0	3.5	-0.4	1.4	0.3	1.6	1.0	0.2	-0.2	1.0	1.9	0.0
Average weekly red wine intake	0.8	1.2	6.5	0.3	-0.3	-0.8	-0.6	-1.1	-2.6	-0.0	-0.7	-1.3	-1.0
Mother’s age at death	0.8	1.0	1.6	1.2	0.5	1.2	0.8	1.2	0.2	-0.3	1.2	1.2	1.2
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	3.0	1.0	0.3	-0.1	1.3	1.7	-0.7	-0.6	1.3	1.0	-0.1
Pack years of smoking	0.8	1.2	4.8	1.0	-0.6	1.1	-1.1	-0.4	1.0	2.2	0.5	-0.3	1.4
Schizophrenia (2018)	0.7	1.5	4.1	2.0	1.3	1.2	0.3	1.0	-0.6	1.1	1.6	0.8	1.3
Reaction Time	0.7	1.4	6.0	-2.5	0.1	-1.0	0.9	-0.9	0.3	-1.6	-0.8	0.2	-1.3
Body Mass Index (BMI) (2010)	0.7	1.0	2.4	-0.7	-1.0	-1.3	-0.5	-0.8	-0.4	-1.4	-1.0	-0.8	-1.6
Cardiovascular Disease	0.7	2.3	4.5	-1.4	-2.1	-1.4	-1.3	-1.1	-1.4	0.0	-2.0	-1.5	-1.8
Medication for hormone replacement therapy	0.7	0.7	1.4	-0.5	-0.4	-0.9	-0.6	-0.8	-1.1	-0.8	-1.1	-0.6	-1.2
Severe depression (siblings)	0.7	0.8	1.9	1.4	-0.3	-0.2	-1.4	-0.3	-1.1	1.3	0.4	-0.9	0.2
Pack years adult smoking proportion	0.7	1.1	4.0	1.2	-0.5	1.1	-1.0	-0.4	1.0	2.0	0.6	-0.2	1.3
Fluid intelligence score	0.7	1.4	3.3	1.4	-0.5	1.4	0.6	1.8	0.2	1.2	1.2	0.5	1.7
Father’s age at death	0.7	1.0	2.8	0.4	-0.8	-0.7	-1.6	-1.7	-0.1	-0.0	-0.9	-1.5	-0.5
Prospective memory result	0.7	0.9	2.7	-0.4	0.2	0.1	-0.6	-1.3	-1.1	0.8	-1.6	-1.4	-0.0
Ever highly irritable/argumentative for 2 days	0.7	0.8	2.7	-0.5	-0.9	-0.6	-0.8	-1.6	-0.5	-0.2	-1.4	-1.1	-0.4
Worry too long after embarrassment	0.7	1.2	3.8	0.6	0.2	1.5	-0.5	1.3	0.1	2.0	0.5	-0.1	1.8
Medication for pain relief, constipation, heartburn	0.7	1.1	4.8	2.2	1.1	1.0	-0.3	0.4	0.3	1.0	1.2	0.2	1.2
Migraine (self-reported)	0.7	0.8	2.1	0.6	-0.1	-0.9	-1.5	-0.7	-1.1	0.3	-0.8	-1.4	-0.8
Mean time to correctly identify matches	0.7	1.3	5.8	-2.4	1.0	-1.0	0.5	-1.0	0.1	-1.3	-0.7	-0.2	-1.5
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.7	0.1	0.4	-1.2	-0.6	-0.7	-1.9	0.2	-0.2	-0.6	-1.0
Illnesses of siblings: Diabetes	0.7	0.8	1.6	-1.3	-1.2	-0.6	-1.1	-0.5	-0.4	-0.3	-1.3	-0.9	-0.8
Loneliness, isolation	0.7	1.0	3.5	-0.4	-1.9	-0.9	-1.2	-0.6	-0.1	0.9	-1.3	-1.0	-0.5
Ever smoked	0.7	1.3	3.8	-0.8	0.6	-1.4	-0.3	-1.1	-1.9	-0.9	-0.7	-0.6	-1.7
Cholesterol lowering medication	0.7	1.1	4.9	0.0	2.2	0.9	1.8	-0.3	0.1	-0.5	0.6	0.9	0.5
Basal cell carcinoma (self-reported)	0.7	0.8	2.0	-0.9	-0.7	-1.2	-0.3	-0.8	-1.1	-0.8	-0.4	-0.7	-1.4
Worry (Nagel 2018)	0.6	1.3	4.1	2.0	-0.5	0.6	-1.6	-0.1	-0.9	1.8	-0.2	-0.3	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.7	6.1	-0.3	-2.5	-0.0	-0.3	-0.5	0.1	0.2	-0.8	-0.4	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	2.6	1.0	0.2	1.6	0.6	1.5	1.6	0.2	1.3	1.1	1.4
Hayfever, allergic rhinitis or eczema	0.6	1.4	3.0	-1.2	-1.1	-1.6	-0.7	-0.0	-1.3	-1.0	-1.7	-0.6	-1.3
Supplements: Glucosamine	0.6	0.8	2.1	-0.1	-1.2	-0.8	-0.9	-1.4	0.6	0.8	-0.7	-1.0	-0.5
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.9	0.1	-1.7	-0.3	0.0	0.4	-1.5	-0.8	-0.5	-0.5	-0.1
Depression (self-reported)	0.6	0.7	1.7	0.6	-0.6	0.6	-0.8	-1.0	-0.3	0.7	-1.3	-1.2	0.7
Birth weight of first child	0.6	1.1	3.1	1.7	-0.1	-0.4	-1.8	-1.0	-1.5	0.2	-0.1	-1.1	-0.5
Qualifications: College or University degree	0.6	1.8	9.7	3.1	0.9	0.8	-1.0	0.5	-1.0	0.7	1.4	0.2	1.2
Medication: Omeprazole	0.6	0.7	1.5	1.0	0.2	-0.6	1.0	0.6	-1.2	-1.2	0.4	0.4	-0.9
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.1	1.2	-0.4	-0.1	-1.3	-0.7	-1.5	0.5	-0.3	-1.1	0.0
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	3.1	-0.9	-0.2	-1.4	0.8	0.1	0.3	-1.8	0.3	1.1	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	3.2	-1.4	-1.8	-0.2	0.3	-0.1	1.0	0.2	-0.7	0.3	-0.1
Average weekly beer plus cider intake	0.6	0.8	1.8	-0.2	1.3	0.9	1.1	1.1	0.6	0.6	0.6	1.0	1.0
Ulcerative Colitis (UC)	0.5	0.9	4.0	0.3	-1.1	-1.2	-0.3	-0.2	-2.0	-0.7	-0.3	-0.3	-1.3
Hand grip strength (left)	0.5	1.4	3.9	1.8	-0.3	0.8	-2.0	0.2	-1.4	0.7	-0.8	-1.4	1.0
Hearing difficulty/problems: Yes	0.5	0.7	3.1	0.9	1.4	0.2	0.3	0.1	-0.6	0.8	1.8	0.1	0.2
Ever used hormone-replacement therapy (HRT)	0.5	0.7	2.9	0.3	0.0	-0.7	-1.7	-1.3	-0.1	0.7	-0.5	-0.8	-0.6
Townsend deprivation index at recruitment	0.5	0.7	2.1	-0.6	-0.4	-1.1	-0.6	-0.1	-1.4	0.2	-0.5	-0.9	-1.0
Maternal smoking around birth	0.5	0.7	2.5	1.6	-0.1	0.7	-0.5	0.5	0.7	0.8	1.1	-0.1	1.1
Relative age voice broke	0.5	0.8	2.1	-0.9	0.5	0.8	0.8	0.7	1.4	0.7	0.5	1.5	0.7
Multivitamins +/- minerals	0.5	0.7	2.1	1.5	-1.5	-0.2	-1.0	0.3	-0.1	0.8	-0.1	-0.8	0.1
Number of incorrect matches in round	0.5	0.8	5.2	-0.2	0.4	-0.2	1.0	0.5	-2.3	-1.1	-0.5	-0.3	-0.4
Impedance of arm (right)	0.5	2.1	4.6	0.6	1.6	1.3	2.2	2.0	0.7	-0.2	1.3	1.9	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	4.5	-0.4	-2.1	-0.7	-0.6	-0.6	-0.6	-0.3	-0.9	-0.9	-0.7
Asthma	0.5	1.0	3.7	-1.9	0.3	-1.4	0.2	0.2	-0.7	-0.7	-1.1	-0.2	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.8	-0.0	0.2	1.0	1.3	0.6	1.0	0.1	0.2	1.0	0.7
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	4.1	0.1	0.7	0.8	2.0	0.1	0.6	-1.4	0.0	0.9	0.5
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.3	-0.5	-1.1	-0.0	-0.6	-0.4	-0.2	1.1	-1.2	-1.1	0.1
Alcohol intake frequency.	0.5	1.1	6.0	-1.6	-1.4	0.4	0.2	-0.0	2.5	-0.1	-0.8	0.2	0.5
Suffer from ‘nerves’	0.5	0.8	1.8	1.3	0.1	0.7	-0.1	1.2	1.0	1.0	0.6	0.8	1.4
Medication: Aspirin	0.5	0.7	3.8	0.1	0.5	-0.8	0.3	-0.4	-1.9	-0.9	-0.1	-0.3	-0.8
Hypertension (Self-reported)	0.5	1.5	2.7	-1.2	-1.2	-0.9	-0.9	-1.2	-1.6	0.1	-1.4	-1.6	-1.3
Illnesses of father: Heart disease	0.5	0.7	2.2	0.1	0.4	0.5	0.8	1.5	0.3	0.5	1.2	1.5	0.4
Friendships satisfaction	0.5	0.6	3.4	0.4	-1.8	0.6	0.2	0.3	-0.3	0.9	-0.0	-0.1	0.9
Osteoporosis (self-reported)	0.5	0.6	1.9	0.4	0.1	-0.5	0.3	0.9	-1.4	-0.3	1.1	1.0	-0.3
Illnesses of father: None of the above (group 1)	0.5	0.7	2.8	-0.0	-0.1	0.1	-0.2	-1.7	-0.7	-0.3	-1.1	-1.4	-0.0
Smoking status: Current	0.5	0.8	2.3	-0.1	-1.0	-1.1	-1.1	-1.0	-0.4	-0.1	-0.6	-1.5	-1.0
Commuting to job workplace: Public transport	0.5	0.6	1.6	-0.0	0.9	1.1	0.5	0.7	1.2	-0.0	0.3	0.7	0.9
High cholesterol (Self-reported)	0.5	0.8	1.5	0.4	1.1	0.7	0.7	0.6	0.9	1.2	1.2	1.0	1.0
Medication: Bendroflumethiazide	0.5	0.7	1.4	-0.9	-0.8	-0.6	-1.1	-0.8	-0.3	0.8	-1.2	-1.1	-0.7
Number of operations (self-reported)	0.5	0.7	2.7	1.6	-0.5	0.1	-0.5	-0.2	-1.5	0.7	-0.0	-0.9	0.3
Diastolic blood pressure, automated reading	0.5	1.6	4.8	0.2	2.2	1.0	2.1	0.9	0.9	0.4	1.0	1.5	0.5
Vascular/heart problems diagnosed by doctor	0.5	1.3	3.4	1.0	0.9	0.8	0.8	1.1	1.8	-0.3	1.1	1.4	1.2
Schizophrenia vs Biploar Disorder	0.4	0.5	2.2	0.1	-0.2	-1.0	-0.1	-0.5	-1.5	-0.5	0.4	-0.1	-1.1
Breast Cancer	0.4	0.9	3.0	-1.4	-0.5	-1.1	0.2	-0.0	-0.0	-1.7	-0.6	0.5	-1.4
Prostate Cancer	0.4	0.5	1.1	0.6	0.7	0.4	0.8	0.1	-0.7	1.0	0.7	0.9	0.5
LDL Cholesterol	0.4	0.6	1.4	0.5	1.2	0.7	0.8	0.2	0.6	0.9	0.7	0.8	0.8
Neuroticism (2016)	0.4	0.5	1.4	0.8	-0.9	-0.0	-0.5	-0.8	-1.2	0.4	-0.7	-0.9	0.3
Blood White Count	0.4	2.7	7.5	0.6	-0.4	-0.7	-2.7	-1.2	-2.7	0.6	-1.4	-2.7	-0.6
Systolic Blood Pressure	0.4	2.2	7.5	-0.9	1.1	1.5	2.7	1.7	1.1	-0.2	0.5	2.3	0.7
Type 2 Diabetes (T2D) (2018)	0.4	0.8	1.6	0.1	-0.5	-0.3	-1.2	-1.1	-1.2	-0.5	-1.0	-1.3	-0.6
Chronotype (morning person)	0.4	0.8	2.7	-0.1	0.6	0.6	1.3	-0.2	1.6	-1.4	0.7	0.3	0.6
Systolic blood pressure, automated reading	0.4	1.2	4.8	-1.0	1.6	0.5	2.2	-0.4	1.1	-0.4	-0.2	1.2	-0.1
Fed-up feelings	0.4	0.8	5.6	-0.7	-2.4	-0.3	0.6	0.2	0.4	0.2	-0.9	0.2	-0.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.8	0.9	0.2	0.3	-0.6	-0.5	-0.0	1.3	0.2	-0.5	0.7
Qualifications: CSEs or equivalent	0.4	0.5	2.7	-1.6	0.3	-0.2	0.8	-0.3	-0.3	-0.7	-0.8	0.2	-0.4
Chronic bronchitis/emphysema (father)	0.4	0.5	1.8	-0.5	-0.5	-0.7	-0.6	-1.3	-0.2	-0.1	-0.5	-0.8	-0.9
Hearing difficulty/problems with background noise	0.4	0.6	2.5	-0.0	1.6	-0.2	0.1	0.4	-0.9	0.8	1.0	0.5	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	3.1	0.8	0.1	1.1	0.5	1.8	1.2	0.1	1.0	1.1	0.9
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.4	-0.4	-0.9	-0.5	-0.3	-1.2	1.6	0.1	-0.3	-0.2	0.2
Neuroticism score	0.4	0.9	2.9	1.2	-1.0	0.9	-0.6	0.7	-0.3	1.7	-0.1	-0.1	1.4
Hair/balding pattern: Pattern 3	0.4	0.7	2.3	-0.5	-0.5	0.9	0.6	1.0	1.5	0.1	0.1	1.0	0.8
Medication: Lansoprazole	0.4	0.4	1.1	0.1	-0.7	0.7	-0.3	-0.7	-0.3	0.7	0.3	-1.0	0.9
Impedance of arm (left)	0.4	1.9	4.0	0.3	1.6	1.2	2.0	1.8	0.9	-0.0	1.4	1.8	1.4
Hair/balding pattern: Pattern 4	0.4	0.9	2.5	-1.6	-0.2	-1.3	0.4	-1.1	0.3	-1.3	-0.4	0.4	-1.1
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.2	-0.1	-0.7	-0.6	-1.0	-0.6	-0.0	0.6	-0.8	-1.1	-0.3
Wheeze or whistling in the chest in last year	0.4	0.7	2.0	-1.2	-0.7	-1.4	0.4	0.5	-0.7	-0.6	-0.6	0.1	-1.2
Health satisfaction	0.4	0.5	1.1	-0.6	-1.0	-0.9	-0.9	-0.2	-0.4	0.1	-0.9	-0.2	-0.8
Neck or shoulder pain in last month	0.4	0.5	2.0	1.4	0.0	0.4	0.7	1.2	-0.0	-0.1	0.8	0.4	0.3
Number of full sisters	0.4	0.5	1.9	-0.1	-0.1	-0.8	-1.4	-0.1	-1.1	0.3	-0.1	-0.9	-0.6
Mood swings	0.4	0.8	1.9	0.3	-1.3	-0.5	-1.3	-0.1	-1.4	0.8	-0.5	-1.1	-0.1
Asthma (self-reported)	0.4	0.8	3.6	-1.9	0.5	-1.2	0.5	0.5	-0.4	-0.7	-0.8	0.2	-1.0
Average weekly champagne plus white wine intake	0.4	0.6	1.4	-0.3	-0.7	-1.0	-1.1	-1.2	-0.3	-0.3	-1.0	-0.5	-0.6
Medication: Blood pressure	0.4	0.7	2.8	0.4	-0.1	-0.4	-0.7	-1.7	-1.1	-0.5	-0.7	-1.1	-0.5
Medication: Atorvastatin	0.4	0.5	1.3	-0.9	0.5	-0.2	1.0	-0.5	-1.1	-0.6	0.5	-0.4	-0.4
Alcohol drinker status: Never	0.4	0.5	1.1	-0.8	-0.8	-0.7	-0.8	-1.1	0.5	-0.6	-0.8	-0.5	-0.5
Commuting to job workplace: Cycle	0.4	0.5	2.0	0.7	-0.5	0.3	-0.5	0.5	1.4	0.2	0.4	0.7	0.6
Supplements: Calcium	0.4	0.4	2.8	0.5	-1.7	0.3	-0.1	0.6	-0.6	0.4	-0.3	-0.1	0.6
Depressed Affect (Nagel 2018)	0.3	0.6	2.2	1.0	-1.0	0.5	-0.9	0.5	-0.5	1.5	-0.0	0.0	0.6
Crohns Disease (2012)	0.3	0.5	2.4	1.5	-0.2	0.5	-0.2	0.8	-0.5	0.8	1.0	0.1	0.4
Mean Putamen Volume	0.3	0.3	0.9	0.1	0.9	0.7	0.6	-0.3	-0.0	0.7	0.5	0.4	0.6
Fasting Glucose	0.3	0.4	2.7	-1.7	-0.1	0.0	-0.3	0.0	0.5	-0.2	-0.7	-0.3	-0.2
Rheumatoid Arthritis	0.3	0.5	1.6	1.1	-0.6	0.3	0.1	-0.5	-0.7	1.3	0.5	0.1	0.5
Blood Eosinophil Count	0.3	2.4	8.6	-1.6	1.4	-0.1	2.9	0.6	0.0	-2.5	-0.2	1.7	-1.0
Hair Pigment	0.3	8.3	14.1	1.2	2.8	3.8	2.6	2.9	3.3	1.6	3.0	3.0	3.6
Supplements: Zinc	0.3	0.4	1.7	0.6	-1.3	-0.2	-0.5	0.2	-0.8	0.2	-0.2	-0.8	0.2
Current tobacco smoking	0.3	0.4	1.0	-0.2	-0.7	-0.9	-0.6	-0.6	-0.2	-0.4	-0.3	-1.0	-0.9
Stomach or abdominal pain in last month	0.3	0.4	1.1	1.1	-0.7	0.0	-0.9	0.5	-0.8	0.7	0.3	-0.2	0.4
High blood pressure (mother)	0.3	0.4	2.0	-0.1	-0.2	0.8	0.6	0.1	1.4	-0.6	-0.0	0.6	0.1
Alcohol usually taken with meals	0.3	0.5	1.4	1.0	-0.0	-0.4	-1.1	-1.2	-0.1	0.0	-0.3	-0.6	-0.3
Had other major operations	0.3	0.3	1.5	-0.0	-1.2	0.3	0.7	0.4	0.8	-0.0	-0.0	0.6	0.3
Qualifications: None of the above	0.3	0.5	3.5	-1.9	0.4	-0.6	0.2	-0.5	0.5	-0.4	-0.5	-0.3	-0.6
Number of children fathered	0.3	0.4	3.1	-0.3	1.8	0.2	0.5	-0.1	-0.0	-0.3	0.5	-0.0	-0.2
Chest pain or discomfort	0.3	0.5	2.8	0.9	-0.0	0.0	-0.3	0.0	-0.7	1.7	0.5	-0.2	0.3
Eye problems/disorders: Cataract	0.3	0.3	1.5	-0.6	0.3	0.1	0.3	-0.0	1.2	-0.9	-0.4	-0.1	0.3
Medication for cholesterol	0.3	0.5	1.2	-0.2	-0.9	0.0	-0.0	1.1	1.1	0.9	0.3	0.6	0.5
Mineral and other dietary supplements	0.3	0.4	1.2	-0.3	0.6	0.5	1.0	1.1	-0.7	-0.6	0.5	0.6	0.1
Breast cancer (self-reported)	0.3	0.3	0.9	-1.0	0.3	0.2	0.8	-0.8	0.7	-0.6	-0.1	0.1	-0.1
Medication: Aspirin	0.3	0.4	3.2	0.8	0.3	-0.4	0.2	-0.4	-1.8	-0.2	0.2	-0.2	-0.3
Miserableness	0.3	0.5	1.9	0.6	-0.4	0.7	1.0	1.4	0.2	0.4	0.4	0.8	0.7
Myopia	0.3	0.4	1.2	-0.0	-0.9	-0.2	-0.7	-0.3	-0.9	0.3	-0.5	-1.1	0.1
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.5	0.3	-0.6	1.1	0.4	1.2	1.2	0.8	1.0	0.3	1.0
Irritable Bowel Disease (IBD)	0.2	0.4	1.2	0.3	-0.8	-0.7	-0.1	0.6	-1.1	-0.7	0.1	0.3	-0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.5	0.8	0.8	-0.9	0.7	-0.0	0.6	0.8	0.7	0.7	-0.1	0.9
Ovarian Cancer	0.2	0.3	1.1	1.0	-0.1	0.5	-0.9	-0.4	0.1	0.3	-0.1	-0.7	0.6
Ulcerative Colitis	0.2	0.3	1.0	0.5	-0.3	-0.1	0.9	0.6	-0.2	-0.4	1.0	0.9	-0.0
Average weekly spirits intake	0.2	0.2	0.7	-0.3	-0.5	-0.6	-0.2	-0.4	-0.8	0.2	-0.7	-0.4	-0.6
Medication: Co-codamol	0.2	0.2	0.9	-0.4	-0.9	-0.1	0.6	0.3	0.5	0.3	0.3	0.5	-0.1
Medication: Metformin	0.2	0.3	1.1	0.6	0.1	-0.0	-1.1	-0.3	-1.0	0.1	-0.6	-0.7	-0.2
Diabetes (father)	0.2	0.2	0.9	1.0	-0.2	0.2	-0.5	0.8	-0.1	0.2	0.4	0.3	0.3
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	-0.5	0.6	0.1	0.2	0.1	-0.5	-0.5	-0.1	0.2	-0.6
Heart attack	0.2	0.2	0.7	0.3	-0.8	0.0	-0.0	0.7	0.1	0.5	0.9	0.3	0.2
Medication: Ramipril	0.2	0.2	0.7	0.0	0.8	-0.2	0.4	-0.3	-0.7	-0.2	0.7	-0.2	-0.4
Pulse wave Arterial Stiffness index	0.2	0.2	0.7	0.3	0.0	0.2	-0.1	0.6	-0.4	0.8	0.8	0.3	0.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.1	0.1	0.1	0.9	1.1	0.4	-0.5	-0.5	-0.2	0.6	0.5
High blood pressure (siblings)	0.2	0.3	1.0	1.0	-0.7	0.7	-0.3	0.0	-0.7	0.0	0.1	-0.8	0.3
Number of full brothers	0.2	0.3	1.0	-0.6	-0.4	-0.2	1.0	-0.4	0.7	-0.6	-0.3	0.2	-0.3
Pulse wave peak to peak time	0.2	0.3	0.9	0.0	-0.3	-0.3	-0.3	-0.8	-0.1	-0.7	-0.9	-0.6	-0.2
Eye problems/disorders: None of the above	0.2	0.3	1.5	0.1	-0.5	0.2	-0.5	-0.2	-0.4	1.2	0.6	-0.1	0.1
Emphysema/chronic bronchitis	0.2	0.2	0.8	0.1	-0.5	-0.3	-0.6	0.5	0.2	0.9	-0.2	-0.4	-0.1
Medication: Blood pressure	0.2	0.4	1.5	0.0	-0.3	-0.2	-1.1	-0.0	-0.7	1.2	-0.0	-0.9	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.9	0.1	0.3	0.4	0.5	0.9	0.7	0.4	0.5	0.5	0.4
Financial situation satisfaction	0.2	0.2	1.3	-0.0	-0.7	0.1	0.3	-0.5	-1.1	-0.0	-0.4	-0.1	-0.1
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.1	0.5	0.4	0.5	-0.4	-0.3	-1.1	0.5	0.3	-0.4	0.4
Supplements: Fish oil (including cod liver oil)	0.2	0.2	1.1	0.6	-0.3	-0.3	-0.4	-0.4	1.1	0.3	0.1	0.0	-0.0
Irritability	0.2	0.3	1.7	0.9	0.4	0.3	-0.2	0.1	-1.3	0.0	-0.3	-0.4	0.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.3	0.1	-0.1	-0.3	-0.4	0.2	-0.5	-0.4	-0.1	-1.2	-0.2
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.8	0.3	-0.9	-0.0	-0.2	0.8	0.1	0.7	0.9	0.2	0.2
Alcohol drinker status: Previous	0.2	0.3	0.8	-0.9	-0.3	0.2	0.7	0.3	0.9	-0.1	-0.3	0.2	0.3
Crohns Disease (2017)	0.1	0.1	0.5	0.1	-0.3	-0.2	0.3	0.6	0.4	-0.3	0.3	0.7	-0.3
Coronary Artery Disease (CAD)	0.1	0.1	0.5	0.2	-0.7	-0.5	0.2	-0.1	0.5	-0.3	0.5	-0.0	-0.2
Triglycerides	0.1	0.2	0.7	-0.5	0.1	-0.2	0.8	0.3	-0.2	-0.5	-0.1	0.4	-0.4
Heel T-Score	0.1	0.9	2.1	-0.3	0.3	1.3	1.5	1.2	1.3	-0.2	0.2	1.1	0.9
Respiratory disease	0.1	0.3	0.5	-0.6	-0.5	-0.5	-0.5	0.6	-0.7	0.4	-0.6	-0.3	-0.2
Hand grip strength (right)	0.1	0.3	1.3	0.7	-0.2	0.4	-1.1	0.5	-0.4	0.3	-0.5	-0.7	0.5
Diabetes (self-reported)	0.1	0.1	0.5	0.4	0.1	0.3	-0.7	-0.3	-0.5	0.2	-0.4	-0.0	0.2
Happiness	0.1	0.2	0.8	0.1	-0.5	0.2	-0.3	0.6	-0.4	0.9	-0.1	-0.1	0.2
Medication: Cholesterol lowering	0.1	0.2	0.5	-0.2	0.4	-0.5	-0.6	0.3	-0.7	0.3	0.6	-0.1	-0.3
Lung cancer (father)	0.1	0.2	0.7	-0.1	-0.8	-0.4	0.1	-0.6	-0.5	0.1	-0.2	-0.3	-0.3
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.7	0.5	0.5	-0.1	-0.2	-0.0	0.1	0.3	0.8	0.1	0.2
Diabetes diagnosed by doctor	0.1	0.1	0.4	0.1	0.1	0.1	-0.5	-0.1	-0.6	-0.4	-0.5	-0.2	-0.2
Qualifications: nursing, teaching	0.1	0.2	0.7	-0.2	0.8	0.6	0.7	-0.2	0.3	-0.4	0.2	0.3	0.4
Wears glasses or contact lenses	0.1	0.1	0.2	-0.2	0.5	-0.1	0.4	-0.2	0.4	-0.5	-0.4	0.1	-0.0
Alzheimer’s Disease (in mother)	0.0	0.1	0.2	0.3	0.4	0.1	0.2	0.3	0.3	-0.1	0.0	0.1	0.1

Hub : Genes

AP3B1

Models

Trait associations