Best TWAS P=2.12e-18 · Best GWAS P=2.16e-19 conditioned to 1.43e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 8.7 | 8.8 | 2.1e-18 | 0.95 | 0.00 | 1.00 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -8.1 | -7.6 | 3.6e-14 | 0.13 | 0.58 | 0.42 | TRUE |