[Hub]/) : Traits : Leg fat mass (right) :

chr5:95,168,155-96,832,363

Best TWAS P=5.55e-11 · Best GWAS P=4.25e-09 conditioned to 8.21e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland ERAP1 0.38 0.14 lasso 7 0.22 1.4e-08 -4.7 -5.1 2.9e-07 -0.05 0.29 0.70 FALSE
2 GTEx Esophagus Gastroesophageal Junction ERAP1 0.29 0.18 lasso 8 0.13 2.6e-05 -4.9 -5.8 7.1e-09 -0.05 0.24 0.57 FALSE
3 GTEx Esophagus Muscularis ERAP1 0.19 0.06 enet 19 0.11 2.5e-07 -3.5 -5.1 2.9e-07 -0.02 0.61 0.35 FALSE
4 GTEx Liver CAST 0.32 0.03 enet 23 0.12 4.4e-04 -4.7 -6.6 5.6e-11 0.15 0.15 0.19 TRUE
5 GTEx Liver ERAP1 0.24 0.15 lasso 3 0.12 3.4e-04 -4.9 -5.2 1.9e-07 -0.02 0.22 0.51 FALSE
6 GTEx Liver CTC-506B8.1 0.34 0.07 enet 22 0.05 1.9e-02 -4.5 -5.2 2.4e-07 -0.04 0.13 0.16 FALSE