Best TWAS P=2.61e-08 · Best GWAS P=7.31e-07 conditioned to 3.69e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | CTC-228N24.3 | 0.15 | 0.09 | lasso | 3 | 0.12 | 8.0e-15 | -4.4 | 5.2 | 1.7e-07 | -0.09 | 0.04 | 0.92 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FLJ33630 | 0.05 | 0.04 | enet | 14 | 0.03 | 2.1e-07 | -4.4 | 5.6 | 2.6e-08 | -0.06 | 0.00 | 0.96 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FLJ33630 | 0.08 | 0.05 | blup | 70 | 0.04 | 4.4e-05 | -4.2 | 5.5 | 3.4e-08 | -0.10 | 0.00 | 0.92 | FALSE |