Best TWAS P=1.18e-11 · Best GWAS P=1.16e-11 conditioned to 0.00967
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PHF2 | 0.07 | 0.06 | lasso | 5 | 0.04 | 0.00055 | 6.7 | 6.8 | 1.2e-11 | 0.75 | 0.01 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PHF2 | 0.02 | 0.01 | blup | 104 | 0.01 | 0.00464 | 6.6 | 6.3 | 2.9e-10 | 0.69 | 0.01 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Esophageal Carcinoma | PHF2 | 0.29 | 0.14 | blup | 103 | 0.16 | 0.00001 | 6.3 | 5.6 | 2.2e-08 | 0.85 | 0.01 | 0.98 | FALSE |