[Hub]/) : Traits : Leg fat mass (right) :

chr9:102,162,230-103,803,109

Best TWAS P=5.92e-10 · Best GWAS P=3.09e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta INVS 0.15 0.10 enet 19 0.12 4.9e-07 6.1 5.4 5.8e-08 0.72 0.03 0.96 FALSE
2 GTEx Cells Transformed fibroblasts INVS 0.16 0.10 enet 17 0.17 8.0e-13 6.1 5.6 2.8e-08 0.61 0.02 0.98 FALSE
3 GTEx Esophagus Muscularis INVS 0.21 0.16 lasso 5 0.22 8.9e-14 6.1 5.4 6.1e-08 0.73 0.03 0.97 FALSE
4 GTEx Heart Atrial Appendage INVS 0.08 0.03 lasso 3 0.04 4.9e-03 -4.4 5.2 2.5e-07 0.77 0.07 0.87 FALSE
5 GTEx Heart Left Ventricle INVS 0.11 0.05 enet 15 0.04 2.6e-03 2.3 5.4 5.3e-08 0.72 0.04 0.84 FALSE
6 GTEx Muscle Skeletal INVS 0.12 0.03 lasso 10 0.10 1.3e-09 6.1 5.5 4.4e-08 0.73 0.03 0.97 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic TEX10 0.10 0.09 lasso 4 0.10 3.1e-06 4.1 5.4 5.9e-08 0.92 0.02 0.98 FALSE
8 GTEx Skin Sun Exposed Lower leg INVS 0.19 0.06 enet 30 0.11 1.5e-09 6.1 6.0 2.4e-09 0.79 0.02 0.98 FALSE
9 GTEx Skin Sun Exposed Lower leg TEX10 0.27 0.27 lasso 8 0.28 7.0e-23 6.3 6.2 5.9e-10 1.00 0.01 0.99 TRUE
10 YFS Blood INVS 0.15 0.14 lasso 7 0.24 1.4e-77 2.6 5.3 8.7e-08 0.78 0.02 0.98 FALSE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma INVS 0.27 0.05 lasso 8 0.13 3.4e-11 4.7 5.3 1.1e-07 0.68 0.09 0.91 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma INVS 0.22 0.04 lasso 9 0.07 7.3e-15 5.8 5.2 2.4e-07 0.71 0.06 0.94 FALSE
13 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma INVS 0.10 0.03 blup 107 0.07 4.0e-04 6.0 5.4 6.8e-08 0.89 0.02 0.94 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma INVS 0.08 0.06 blup 106 0.07 7.0e-09 -4.2 5.5 4.5e-08 0.70 0.61 0.39 FALSE
15 The Cancer Genome Atlas Lung Squamous Cell Carcinoma INVS 0.09 0.02 enet 11 0.04 4.0e-05 4.7 5.5 3.2e-08 0.66 0.03 0.74 FALSE
16 The Cancer Genome Atlas Pancreatic Adenocarcinoma INVS 0.16 0.12 enet 8 0.08 2.8e-04 5.8 6.1 9.4e-10 0.77 0.02 0.96 FALSE
17 The Cancer Genome Atlas Prostate Adenocarcinoma INVS 0.09 0.04 enet 14 0.06 1.5e-06 4.7 5.3 8.8e-08 0.75 0.05 0.93 FALSE