Best TWAS P=2.29e-08 · Best GWAS P=9.47e-09 conditioned to 0.0523
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | SLC35A1 | 0.30 | 0.48 | enet | 25 | 0.50 | 5.7e-73 | 5.4 | 5.2 | 2.4e-07 | 0.95 | 0.03 | 0.97 | FALSE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SLC35A1 | 0.02 | 0.01 | blup | 72 | 0.00 | 8.7e-02 | 5.4 | -5.6 | 2.3e-08 | -0.84 | 0.01 | 0.90 | TRUE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | SLC35A1 | 0.04 | 0.03 | lasso | 5 | 0.02 | 1.3e-02 | 5.4 | -5.3 | 1.4e-07 | -0.94 | 0.01 | 0.90 | FALSE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | SLC35A1 | 0.14 | 0.04 | blup | 72 | 0.07 | 1.4e-03 | 1.7 | -5.2 | 2.5e-07 | -0.78 | 0.01 | 0.82 | FALSE |