Best TWAS P=7.32e-09 · Best GWAS P=1.36e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | DAGLB | 0.09 | 0.06 | lasso | 5 | 0.06 | 4.8e-08 | 5.8 | -5.8 | 7.3e-09 | -0.98 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | DAGLB | 0.06 | 0.02 | blup | 71 | 0.03 | 7.4e-04 | 3.7 | -5.3 | 1.1e-07 | -0.72 | 0.02 | 0.69 | FALSE |