[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr7:1,787,236-3,581,391

Best TWAS P=6.07e-41 · Best GWAS P=3.52e-41 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
22	ROSMAP	Brain Pre-frontal Cortex	AMZ1	0.09	0.05	lasso	6	0.04	2.4e-06	-13.3	13.4	6.1e-41	-0.92	0.02	0.98	TRUE
13	GTEx	Nerve Tibial	GNA12	0.31	0.34	lasso	7	0.36	9.6e-27	-8.7	-11.1	8.2e-29	0.84	0.88	0.12	TRUE
1	CommonMind	Brain Pre-frontal Cortex	AMZ1	0.19	0.12	enet	22	0.13	5.7e-16	6.1	7.6	2.7e-14	-0.45	1.00	0.00	TRUE
14	GTEx	Skin Not Sun Exposed Suprapubic	GNA12	0.10	0.15	lasso	3	0.12	4.2e-07	6.6	-7.4	1.5e-13	0.51	0.44	0.54	TRUE
16	GTEx	Skin Sun Exposed Lower leg	AC004840.9	0.18	0.01	enet	36	0.02	3.7e-03	2.9	-5.3	1.4e-07	0.14	0.19	0.16	TRUE
5	GTEx	Cells EBV-transformed lymphocytes	GNA12	0.46	0.51	lasso	5	0.50	7.9e-19	-13.4	-13.3	1.5e-40	0.95	0.01	0.99	FALSE
19	GTEx	Whole Blood	GNA12	0.09	0.01	enet	4	0.00	3.3e-01	-13.2	-13.1	2.5e-39	0.95	0.02	0.92	FALSE
11	GTEx	Esophagus Muscularis	GNA12	0.32	0.31	lasso	3	0.34	2.1e-21	-13.3	-13.0	9.9e-39	0.96	0.01	0.99	FALSE
10	GTEx	Esophagus Mucosa	GNA12	0.16	0.13	lasso	3	0.13	3.0e-09	-13.1	-12.2	3.6e-34	0.88	0.03	0.97	FALSE
24	The Cancer Genome Atlas	Esophageal Carcinoma	AMZ1	0.18	0.05	blup	69	0.05	1.4e-02	8.2	-11.6	3.9e-31	0.74	0.01	0.70	FALSE
4	GTEx	Artery Tibial	GNA12	0.24	0.13	enet	20	0.22	3.5e-17	-13.3	-11.6	6.1e-31	0.86	0.02	0.98	FALSE
9	GTEx	Esophagus Gastroesophageal Junction	GNA12	0.20	0.12	lasso	6	0.12	3.4e-05	-8.8	-11.5	1.2e-30	0.84	0.04	0.94	FALSE
6	GTEx	Cells Transformed fibroblasts	GNA12	0.21	0.11	lasso	11	0.15	1.7e-11	-13.3	-11.3	1.4e-29	0.88	0.02	0.98	FALSE
7	GTEx	Colon Sigmoid	GNA12	0.14	0.05	lasso	3	0.03	3.6e-02	-8.5	-11.2	3.0e-29	0.83	0.04	0.87	FALSE
12	GTEx	Lung	GNA12	0.16	0.08	enet	21	0.12	1.2e-09	-13.1	-11.2	5.7e-29	0.77	0.03	0.97	FALSE
15	GTEx	Skin Sun Exposed Lower leg	GNA12	0.17	0.16	lasso	3	0.18	1.3e-14	-8.6	-11.2	6.4e-29	0.88	0.17	0.83	FALSE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	GNA12	0.03	0.01	enet	7	0.02	1.5e-03	5.6	-10.8	2.9e-27	0.78	0.06	0.76	FALSE
2	GTEx	Adipose Subcutaneous	GNA12	0.11	0.08	lasso	4	0.07	1.3e-06	-8.8	-9.6	6.8e-22	0.73	0.23	0.77	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	AMZ1	0.04	0.04	lasso	3	0.02	1.3e-03	8.2	9.5	1.9e-21	-0.63	0.03	0.91	FALSE
17	GTEx	Small Intestine Terminal Ileum	GNA12	0.34	0.20	lasso	5	0.16	2.4e-04	-8.7	-9.4	6.0e-21	0.74	0.09	0.72	FALSE
21	NTR	Blood	GNA12	0.07	0.03	bslmm	597	0.06	1.3e-17	-9.4	-9.2	2.4e-20	0.61	0.94	0.06	FALSE
20	METSIM	Adipose	GNA12	0.07	0.05	lasso	3	0.05	3.3e-08	-8.7	-8.8	9.4e-19	0.75	0.18	0.82	FALSE
25	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GNA12	0.03	0.04	lasso	1	0.04	3.0e-05	-8.8	-8.8	2.0e-18	0.69	0.10	0.70	FALSE
18	GTEx	Stomach	GNA12	0.18	0.16	lasso	2	0.13	6.6e-07	-8.5	-8.6	5.4e-18	0.67	0.46	0.54	FALSE
23	YFS	Blood	GNA12	0.23	0.15	bslmm	570	0.25	4.5e-82	5.4	-8.0	1.0e-15	0.51	1.00	0.00	FALSE
8	GTEx	Colon Transverse	GNA12	0.19	0.08	lasso	4	0.10	2.3e-05	6.6	-7.8	6.9e-15	0.62	0.36	0.61	FALSE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	AMZ1	0.08	0.01	blup	71	0.05	1.3e-05	-8.8	6.3	3.7e-10	-0.64	0.05	0.76	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	AMZ1	0.32	0.04	enet	19	0.20	3.3e-19	-9.4	5.8	6.1e-09	-0.56	0.18	0.82	FALSE
3	GTEx	Adipose Visceral Omentum	AC004840.9	0.37	0.04	enet	52	0.15	3.3e-08	-2.7	-5.2	1.6e-07	-0.03	0.35	0.03	FALSE