Best TWAS P=1.54e-08 · Best GWAS P=9.88e-08 conditioned to 0.0174
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | C8orf46 | 0.19 | 0.06 | enet | 11 | 0.03 | 1.6e-02 | -4.1 | 5.2 | 1.6e-07 | -0.62 | 0.09 | 0.58 | FALSE |
| 2 | GTEx | Esophagus Muscularis | C8orf46 | 0.39 | 0.22 | enet | 30 | 0.18 | 8.5e-11 | 4.3 | 5.7 | 1.5e-08 | -0.61 | 0.38 | 0.56 | TRUE |