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Traits
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Leg fat-free mass (right)
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chr8:66,679,221-68,096,452
Best TWAS P=1.54e-08 · Best GWAS P=9.88e-08 conditioned to 0.0174
66.6M
66.8M
67M
67.2M
67.4M
67.6M
67.8M
68M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Esophagus Muscularis
C8orf46
0.39
0.22
enet
30
0.18
8.5e-11
4.3
5.7
1.5e-08
-0.61
0.38
0.56
TRUE
1
GTEx
Colon Transverse
C8orf46
0.19
0.06
enet
11
0.03
1.6e-02
-4.1
5.2
1.6e-07
-0.62
0.09
0.58
FALSE