Best TWAS P=1.64e-08 · Best GWAS P=1.23e-10 conditioned to 0.00045
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | DDAH1 | 0.26 | 0.21 | lasso | 6 | 0.20 | 8.7e-08 | 4.2 | -5.5 | 4.0e-08 | -0.05 | 0.11 | 0.88 | FALSE |
| 2 | GTEx | Liver | DDAH1 | 0.36 | 0.42 | lasso | 6 | 0.43 | 2.8e-13 | -4.7 | 5.2 | 2.1e-07 | 0.09 | 0.10 | 0.90 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | C1orf52 | 0.05 | 0.02 | blup | 564 | 0.03 | 9.5e-05 | 3.0 | 5.2 | 1.5e-07 | 0.01 | 0.29 | 0.54 | FALSE |
| 4 | YFS | Blood | BCL10 | 0.24 | 0.12 | enet | 48 | 0.19 | 1.1e-59 | 4.2 | 5.6 | 2.5e-08 | -0.03 | 0.61 | 0.37 | TRUE |
| 5 | YFS | Blood | ODF2L | 0.04 | 0.04 | enet | 18 | 0.04 | 1.8e-12 | 6.3 | -5.7 | 1.6e-08 | -0.91 | 0.00 | 1.00 | TRUE |