Best TWAS P=8.49e-10 · Best GWAS P=2.43e-12 conditioned to 1.2e-11
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | PARD3 | 0.06 | 0.03 | lasso | 5 | 0.03 | 9.2e-04 | 2.8 | 6.1 | 8.5e-10 | -0.04 | 0.16 | 0.55 | TRUE |
2 | GTEx | Adipose Visceral Omentum | PARD3 | 0.22 | 0.05 | enet | 26 | 0.08 | 9.1e-05 | 2.6 | 5.8 | 5.9e-09 | -0.14 | 0.37 | 0.41 | FALSE |