TWAS hub - PARD3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0760	0.0290	1.3e-03	0.008	0.030	0.014	0.029	0.012	3.4e-02	1.3e-04	6.1e-03	0.00016	1.1e-02
2	GTEx	Adipose Subcutaneous	0.0580	0.0270	7.6e-03	0.027	NA	0.019	NA	0.033	2.5e-03	NA	1.1e-02	NA	9.2e-04
3	GTEx	Adipose Visceral Omentum	0.2210	0.0660	1.8e-04	0.055	NA	0.076	NA	0.074	8.3e-04	NA	9.1e-05	NA	1.1e-04
4	GTEx	Cells EBV-transformed lymphocytes	0.2870	0.1080	3.3e-03	0.189	NA	0.043	NA	0.145	9.2e-07	NA	1.6e-02	NA	1.9e-05
5	GTEx	Cells Transformed fibroblasts	0.1490	0.0410	7.2e-06	0.069	NA	0.112	NA	0.122	7.0e-06	NA	9.1e-09	NA	2.0e-09
6	GTEx	Muscle Skeletal	0.0779	0.0314	9.1e-04	0.023	NA	0.046	NA	0.052	2.3e-03	NA	2.6e-05	NA	8.1e-06
7	GTEx	Thyroid	0.2010	0.0490	4.6e-08	0.106	NA	0.151	NA	0.160	1.6e-08	NA	1.2e-11	NA	3.0e-12
8	TCGA	Prostate Adenocarcinoma	0.0517	0.0246	6.3e-03	-0.001	0.009	0.006	NA	0.003	4.9e-01	3.6e-02	6.6e-02	NA	1.4e-01
9	TCGA	Thyroid Carcinoma	0.1080	0.0430	2.0e-04	0.015	0.054	0.044	NA	0.039	1.1e-02	5.2e-06	4.2e-05	NA	9.8e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Number of operations (self-reported)	5.2	7.7	17.3	-4.2	-3.9	-3.6	-2.5	-1.5	-1.7	-2.8	1.8	1.3
Had major operations	3.8	4.5	8.8	-2.7	-2.6	-3.0	-1.4	-2.1	-1.6	-1.3	1.7	1.9
Financial difficulties in last 2 years	3.7	5.0	10.3	1.5	3.2	2.4	3.2	0.7	3.0	2.3	0.4	1.2
Commuting to job workplace: Walk	3.5	3.7	7.1	1.7	2.4	1.1	2.1	1.2	2.7	2.6	1.4	1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.4	4.0	9.0	1.8	1.9	1.3	3.0	0.5	2.5	2.4	1.2	2.2
Irritability	3.4	5.8	10.5	1.1	3.2	2.5	2.9	0.9	3.1	2.8	1.3	2.2
Pulse rate	3.1	5.3	11.7	-1.6	-3.2	-3.4	-3.4	0.3	-0.9	-2.8	1.4	-0.8
Alcohol drinker status: Never	3.1	3.7	8.4	-0.3	2.3	0.8	2.2	-0.1	2.4	2.1	2.0	2.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.9	6.1	14.6	1.1	3.8	3.3	3.3	1.6	2.4	3.0	0.4	0.2
Current tobacco smoking	2.8	4.5	11.2	-3.4	-2.8	-2.1	-1.7	-2.0	-2.2	-1.9	0.7	0.9
Leg fat-free mass (right)	2.8	14.8	37.7	4.1	6.1	5.8	3.0	2.7	3.6	3.7	-1.0	0.7
Smoking status: Current	2.8	4.5	12.0	-3.5	-2.7	-2.1	-1.6	-2.0	-2.0	-1.8	1.1	1.1
Leg predicted mass (right)	2.8	15.1	38.0	4.2	6.2	5.9	3.0	2.8	3.6	3.7	-1.1	0.6
Leg fat-free mass (left)	2.7	14.3	36.3	4.0	6.0	5.9	2.9	2.6	3.4	3.7	-0.9	0.6
Leg predicted mass (left)	2.7	14.3	36.1	4.0	6.0	5.8	2.9	2.6	3.4	3.7	-0.9	0.6
Hearing difficulty/problems with background noise	2.7	4.3	12.1	-0.1	1.7	0.4	1.8	0.3	2.7	1.4	3.3	3.5
Depression (self-reported)	2.7	3.2	5.0	1.8	2.1	2.2	2.2	1.1	2.1	2.1	0.8	1.1
Body Mass Index (BMI) (2010)	2.6	3.6	10.2	1.3	3.2	3.1	2.0	0.4	1.5	2.0	0.5	0.4
Type 2 Diabetes (T2D) (2012)	2.4	2.8	4.9	-1.1	1.8	-0.1	2.2	-1.7	1.4	2.0	1.7	2.1
Weight	2.4	11.7	29.1	3.0	5.4	5.3	2.8	2.0	3.7	3.4	-0.2	1.1
Shortness of breath walking on level ground	2.4	2.9	15.8	-4.0	-0.6	-1.2	0.1	-2.1	-0.7	-0.5	1.3	1.2
Basal metabolic rate	2.4	13.3	33.4	3.9	5.8	5.7	2.6	2.7	3.4	3.4	-0.9	0.6
Waist circumference	2.3	8.5	22.6	2.0	4.8	4.2	2.9	0.2	3.0	3.6	0.5	1.2
Hair/balding pattern: Pattern 3	2.3	3.5	8.7	-1.3	1.0	0.8	2.9	-1.6	2.1	2.3	1.4	2.3
Average weekly fortified wine intake	2.2	2.6	5.0	-2.2	-1.4	-2.2	0.0	-1.6	-1.3	-0.5	2.2	1.3
Qualifications: NVQ or HND or HNC or equivalent	2.2	2.7	6.9	-2.6	-0.9	-2.0	-0.5	-2.0	-0.6	-1.0	1.7	1.9
Whole body fat-free mass	2.2	12.4	31.1	4.0	5.6	5.5	2.4	2.7	3.1	3.2	-1.0	0.4
Whole body water mass	2.2	12.6	31.8	4.1	5.6	5.6	2.4	2.7	3.1	3.2	-1.0	0.3
Arm fat-free mass (left)	2.2	10.9	28.2	3.7	5.3	5.2	2.2	2.3	3.1	2.9	-0.7	0.4
Impedance of leg (right)	2.1	9.9	27.1	-3.9	-5.2	-4.8	-2.5	-1.6	-2.2	-3.2	0.5	-0.3
Medication: Levothyroxine sodium	2.1	3.6	9.6	-1.6	1.1	0.3	2.3	-2.1	1.0	1.6	2.5	3.1
Impedance of leg (left)	2.1	10.2	26.6	-4.2	-5.2	-4.9	-2.5	-1.6	-2.0	-3.3	0.6	0.0
Commuting to job workplace: Car/motor vehicle	2.1	2.4	4.5	-2.1	-2.1	-1.2	-1.4	-0.1	-1.3	-2.1	-1.5	-1.1
Arm fat mass (left)	2.1	8.5	21.3	2.1	4.5	4.6	2.8	1.0	3.2	3.2	0.2	1.4
Alcohol drinker status: Previous	2.1	2.3	3.5	-1.7	0.9	-0.5	1.7	-1.5	1.9	1.7	1.5	1.8
Ever had hysterectomy (womb removed)	2.0	2.3	6.8	-0.8	-1.8	-1.8	-2.2	0.9	-0.5	-2.6	0.5	-0.6
Arm fat mass (right)	2.0	8.1	21.4	2.1	4.4	4.6	2.5	1.3	3.1	3.0	-0.0	1.1
Arm predicted mass (left)	2.0	10.3	27.2	3.5	5.2	5.0	2.2	2.3	3.1	2.9	-0.4	0.7
Major Depression (MDD)	1.9	2.4	4.3	-0.7	-1.9	-1.5	-2.0	-0.6	-2.0	-2.1	-0.9	-1.4
Trunk fat mass	1.9	8.2	19.8	1.9	4.4	4.5	2.8	1.3	3.3	3.0	0.1	1.4
Had other major operations	1.9	2.3	4.5	-1.8	-2.0	-0.8	-2.0	-0.5	-1.6	-2.1	-0.3	-1.0
Ulcerative Colitis (UC)	1.8	3.4	10.1	-2.4	-0.2	-1.3	1.5	-2.1	0.7	1.1	3.2	2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.3	5.3	-0.5	1.9	0.5	1.7	-0.3	2.3	1.9	1.4	1.8
Arm fat-free mass (right)	1.8	9.3	24.5	3.5	4.9	4.7	1.8	2.3	2.9	2.9	-0.3	0.5
Arm predicted mass (right)	1.8	9.1	24.1	3.6	4.9	4.7	1.7	2.2	2.5	2.7	-0.6	0.3
Pain type(s) experienced in last month: Hip pain	1.8	2.3	6.9	-1.0	-1.9	-2.6	-2.3	-0.8	-0.9	-1.5	0.6	0.1
Schizophrenia vs Biploar Disorder	1.7	2.2	5.4	1.0	-1.0	-0.2	-1.3	2.3	0.7	-1.5	-1.8	-2.2
Body mass index (BMI)	1.7	7.4	18.7	2.1	4.2	4.3	2.3	1.0	3.0	3.1	0.6	1.0
Trunk fat-free mass	1.7	9.8	24.9	3.7	5.0	5.0	1.9	2.6	2.6	2.6	-1.1	0.1
Frequency of tiredness / lethargy in last 2 weeks	1.7	2.8	9.3	-0.5	1.3	-0.1	1.7	1.5	3.1	1.7	1.9	1.4
Trunk predicted mass	1.7	9.8	24.8	3.7	5.0	5.0	1.9	2.5	2.6	2.7	-1.0	0.2
Pulse wave reflection index	1.7	2.1	6.2	0.7	1.9	2.5	1.8	0.1	0.9	1.8	-0.9	0.1
Whole body fat mass	1.7	7.1	18.6	1.6	4.1	4.3	2.4	1.2	3.1	2.8	0.2	1.4
Alcohol intake frequency.	1.7	4.1	10.4	0.9	3.2	1.8	2.6	0.4	2.7	2.7	-0.2	0.9
Severe depression (siblings)	1.6	1.8	5.2	0.5	1.2	0.9	0.9	0.8	1.3	0.7	2.1	2.3
Forced vital capacity (FVC), Best measure	1.6	6.0	12.2	1.7	3.5	3.2	2.4	2.6	2.9	2.6	-0.9	-0.2
Leg pain on walking	1.6	2.0	11.2	-3.3	-1.0	-1.7	-0.9	-0.7	-0.2	-0.6	0.9	0.7
Knee pain experienced in last month	1.6	2.4	5.2	-2.2	-0.5	-2.1	-1.0	-2.3	-0.8	-0.7	1.8	1.4
Number of self-reported non-cancer illnesses	1.6	2.8	7.9	-2.8	-1.4	-1.5	-0.7	-2.5	-2.0	-0.7	0.7	1.1
Leg fat mass (left)	1.6	6.2	15.9	1.1	3.8	4.0	2.2	0.8	3.0	2.7	0.6	1.6
Alzheimer’s Disease (in mother)	1.5	1.8	6.7	0.1	0.6	0.3	1.1	0.5	2.6	1.1	1.5	2.0
Ulcerative Colitis	1.5	2.2	7.8	-2.0	-0.4	-1.8	1.0	-0.6	1.2	0.3	2.8	1.3
Health satisfaction	1.5	1.9	8.7	-2.9	-1.2	-1.7	-1.1	0.4	0.2	-1.2	1.1	0.4
Arm fat percentage (right)	1.4	5.5	13.6	1.2	3.5	3.7	2.5	0.4	2.6	2.7	0.6	1.4
Hip circumference	1.4	6.2	17.7	1.7	4.2	3.5	2.3	0.4	2.6	2.8	0.5	1.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.6	9.4	1.6	3.1	2.7	1.5	2.7	2.7	2.2	-0.5	-0.3
Leg fat mass (right)	1.4	5.6	16.2	1.1	3.6	4.0	2.0	0.9	2.8	2.5	0.3	1.3
Arm fat percentage (left)	1.4	5.7	12.9	1.0	3.5	3.6	2.6	0.3	2.7	2.9	0.7	1.6
Average weekly red wine intake	1.4	2.0	5.5	-0.7	-1.1	-0.9	-1.8	-0.5	-2.4	-2.2	-0.8	-0.9
Myopia	1.4	2.0	6.2	1.1	1.1	0.1	0.7	-0.6	1.3	1.8	2.5	1.9
Impedance of whole body	1.4	7.3	18.9	-3.7	-4.3	-4.3	-1.5	-1.9	-1.8	-2.4	0.3	0.1
Worry (Nagel 2018)	1.3	2.8	7.7	-1.8	-1.6	-2.8	-2.2	1.6	0.2	-1.8	0.9	-0.5
Smoking Status	1.3	3.1	8.4	-2.9	-1.6	-1.4	-0.2	-1.5	-0.6	-0.9	2.6	2.1
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	4.9	0.1	2.2	1.0	2.0	-0.4	0.8	1.8	-0.0	1.2
Trunk fat percentage	1.3	5.2	11.5	1.1	3.4	3.3	2.5	0.6	2.9	2.5	0.6	1.4
Maternal smoking around birth	1.3	1.8	7.1	0.7	1.5	1.3	0.3	2.7	1.6	-0.0	-1.1	-1.0
Medication: Ramipril	1.3	1.7	4.9	-2.2	-1.4	-1.8	-0.9	-1.6	-0.9	-1.0	-0.1	-0.1
Exposure to tobacco smoke at home	1.3	1.5	2.9	-1.7	-1.6	-1.2	-1.4	-0.8	-0.6	-1.6	0.6	0.5
Medication: Paracetamol	1.3	2.0	4.4	-1.2	1.6	0.4	2.0	-2.1	1.2	1.6	1.0	0.8
Fasting Glucose	1.2	1.4	3.7	-1.1	1.0	-1.1	0.3	-1.8	-0.2	0.5	1.9	1.3
BMI	1.2	6.7	18.7	2.2	4.3	3.9	2.5	0.4	2.3	2.9	1.1	0.8
Hearing difficulty/problems: Yes	1.2	1.9	7.3	-0.3	0.6	-0.2	0.9	-1.2	1.1	0.8	2.7	2.2
Sitting height	1.2	8.4	22.7	2.9	3.9	4.8	1.8	2.9	2.4	1.9	-2.8	-0.1
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	2.9	0.3	1.3	1.5	1.2	1.2	1.6	1.7	0.4	0.7
Asthma	1.2	2.4	5.5	-1.8	-1.4	-2.1	-0.6	-2.4	-1.7	-1.0	0.4	1.2
Number of full brothers	1.2	1.5	3.8	0.3	-1.6	-1.3	-1.9	0.1	-0.4	-1.9	1.1	0.9
Worry too long after embarrassment	1.2	2.0	4.5	-0.6	-1.5	-1.7	-2.1	2.1	0.2	-1.7	-0.5	-0.6
Mouth/teeth dental problems: Loose teeth	1.2	1.5	3.7	0.9	-0.6	0.5	-1.5	0.7	-1.0	-1.7	-1.2	-1.9
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	3.0	-0.3	-0.9	-1.2	-1.7	0.7	-0.8	-1.7	-1.0	-1.7
Supplements: Vitamin C	1.2	1.5	4.2	-1.0	1.4	1.1	1.6	-2.1	0.0	1.2	0.5	0.5
Asthma (self-reported)	1.2	2.5	5.1	-1.9	-1.5	-2.3	-0.7	-2.2	-1.7	-1.1	0.5	1.2
Ever had prostate specific antigen (PSA) test	1.2	1.4	3.1	-1.7	-1.5	-1.2	-1.3	-0.0	-0.7	-1.8	-0.0	-0.7
Neuroticism (Nagel 2018)	1.1	2.6	6.6	-1.5	-1.9	-2.6	-2.2	1.5	-0.1	-1.8	0.0	-0.6
Alzheimer’s Disease (including proxy)	1.1	1.5	4.3	-0.1	0.1	-0.9	0.5	0.8	2.1	0.0	2.0	1.9
Reaction Time	1.1	2.0	4.1	1.1	1.9	1.2	1.4	1.6	2.0	1.5	0.5	-0.9
Bipolar Disorder (2011)	1.1	1.0	3.9	-1.2	-0.8	-1.1	-0.3	-1.1	-2.0	-0.1	-0.7	-0.6
Diabetes (father)	1.1	1.4	3.7	1.9	0.8	1.9	0.1	0.7	0.4	0.3	-1.8	-0.8
Ever unenthusiastic/disinterested for a whole week	1.1	1.3	3.0	-0.3	1.4	0.7	1.5	-0.7	0.0	1.7	0.7	1.7
Hypothyroidism/myxoedema (self-reported)	1.1	2.1	4.4	-0.8	1.2	0.1	1.6	-1.9	0.7	1.3	2.0	2.1
Body fat percentage	1.1	4.4	9.9	0.7	3.0	3.1	2.1	0.5	2.7	2.3	0.8	1.4
Medication: Gliclazide	1.1	1.2	5.9	-1.3	0.1	0.3	0.3	-2.4	-1.1	1.1	-0.6	0.7
Eye problems/disorders: Glaucoma	1.1	1.3	5.2	-1.2	-0.8	-0.3	-0.5	-1.2	-0.8	-0.5	2.3	1.3
Medication: Lisinopril	1.1	1.5	4.4	-1.4	0.2	0.8	1.4	-0.6	0.9	1.5	2.1	0.9
Illnesses of father: High blood pressure	1.1	1.3	3.2	0.0	0.8	1.4	1.4	-0.6	1.3	0.9	1.2	1.8
Heel T-Score	1.0	7.8	36.0	3.4	0.7	1.5	-1.4	6.0	2.1	-0.8	-2.3	-2.8
Allergy or Eczema	1.0	2.7	5.2	0.2	2.1	0.2	2.2	-1.5	1.7	2.3	1.3	1.8
Medication: Co-codamol	1.0	1.2	5.1	-2.3	-0.6	-1.2	-0.2	-1.5	-1.2	-0.4	0.2	0.3
Diabetes (mother)	1.0	1.2	3.4	-1.6	0.4	0.1	1.1	-0.5	0.3	1.1	1.5	1.8
Age when periods started (menarche)	1.0	2.4	7.7	0.1	-1.1	-1.4	-0.9	-0.2	-1.6	-1.6	-2.2	-2.8
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	3.0	-1.3	-1.3	-0.8	-1.7	0.6	0.7	-1.6	0.0	-0.6
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	4.9	-0.1	-0.3	0.5	-0.2	-1.0	-2.2	-0.3	-1.5	-1.2
Hayfever, allergic rhinitis or eczema	1.0	2.1	4.0	-0.1	1.9	-0.2	1.9	-1.5	1.5	2.0	1.0	1.6
Forced vital capacity (FVC)	1.0	3.8	7.2	1.6	2.7	2.6	1.4	2.6	1.9	1.5	-1.6	-0.9
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	8.1	1.5	2.8	2.2	1.2	2.3	2.1	1.8	-0.6	-0.3
Lung cancer (father)	1.0	1.2	2.5	0.9	1.6	0.7	1.4	0.3	1.1	1.6	-0.8	0.5
Loud music exposure frequency	1.0	1.1	2.6	1.3	0.8	1.2	1.0	1.1	1.6	0.9	-0.5	-0.0
Family relationship satisfaction	1.0	1.3	4.3	-0.3	1.1	-0.2	1.3	-0.8	0.9	0.9	1.4	2.1
Supplements: Fish oil (including cod liver oil)	1.0	1.4	4.1	-1.2	-1.1	-1.0	-2.0	-0.2	-1.1	-1.2	-0.7	-1.2
Medication: Bendroflumethiazide	1.0	1.6	5.4	1.1	1.8	2.3	1.7	0.4	0.9	0.9	-0.1	-0.0
Irritable Bowel Disease (IBD)	0.9	2.2	6.6	-2.3	0.4	-1.5	1.4	-1.4	0.7	1.0	2.6	0.6
Neuroticism (2016)	0.9	1.3	5.3	-0.2	-1.0	-2.3	-1.4	0.3	-0.8	-1.6	-0.0	-0.6
Lung FVC	0.9	4.7	11.0	1.4	2.1	2.9	1.9	3.3	2.4	2.0	-1.2	-1.2
Neuroticism	0.9	2.2	4.6	-0.2	-1.2	-2.0	-2.1	1.9	-0.5	-1.9	-0.8	-1.5
Relative age voice broke	0.9	1.4	7.2	1.2	0.0	0.1	-0.0	2.7	1.9	0.2	0.2	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	9.0	1.6	0.8	0.4	-1.4	3.0	1.9	-0.9	0.5	-0.1
Medication: Simvastatin	0.9	1.3	4.9	-1.2	0.7	0.7	0.5	-2.2	-1.6	0.7	0.3	1.0
Pulse wave Arterial Stiffness index	0.9	1.0	2.0	1.1	1.4	1.4	0.7	0.4	0.6	1.1	-1.1	-0.6
Impedance of arm (left)	0.9	4.2	10.2	-3.0	-3.2	-3.1	-0.5	-1.9	-1.5	-1.4	-0.0	0.3
Medication: Ventolin 100micrograms inhaler	0.9	1.1	3.0	-1.0	-1.2	-1.7	-1.0	-0.6	-0.6	-0.9	0.6	1.4
Comparative body size at age 10	0.9	2.6	5.2	1.2	2.2	1.2	1.5	0.1	1.5	2.0	2.3	1.5
Medication: Ibuprofen	0.9	1.1	2.6	-1.6	0.4	-1.3	0.2	0.3	1.3	-0.2	1.6	0.9
Medication: Seretide 50 evohaler	0.9	1.1	3.6	-1.9	-0.5	-1.5	-0.7	0.8	0.4	-0.8	1.1	0.7
Medication: Aspirin	0.9	1.2	3.9	0.6	-0.4	1.2	-0.5	1.8	-0.1	0.3	-2.0	-1.2
Hypertension (Self-reported)	0.9	2.5	7.5	-1.4	-1.6	-1.0	-0.7	-2.7	-2.6	-0.9	-1.0	-0.7
Illnesses of father: Heart disease	0.9	1.3	2.2	0.6	-1.4	-0.6	-1.5	0.2	-1.2	-1.3	-1.5	-1.2
Qualifications: nursing, teaching	0.9	1.5	4.9	-1.5	-2.2	-1.0	-1.3	0.0	-1.0	-1.3	-0.0	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	3.9	1.2	1.1	1.2	1.5	-1.2	0.4	2.0	0.0	1.3
Guilty feelings	0.9	1.4	4.5	-0.5	-1.1	-1.8	-0.4	2.1	0.9	-0.7	0.9	0.8
Ever taken oral contraceptive pill	0.9	1.0	2.7	0.5	-1.3	-0.0	-1.6	1.0	-0.9	-1.3	-1.1	-0.5
Tinnitus: Yes, now most or all of the time	0.9	1.0	2.5	-1.3	-0.1	0.5	0.9	-1.6	-0.7	1.4	-0.2	1.3
Commuting to job workplace: Public transport	0.9	1.1	3.0	1.7	1.1	1.7	-0.2	0.8	0.3	0.0	-0.9	-1.0
Diastolic blood pressure, automated reading	0.9	2.7	5.2	-0.1	-1.3	0.2	-2.1	0.4	-1.8	-2.3	-2.2	-2.1
Ever depressed for a whole week	0.9	1.1	3.1	-0.1	1.8	0.7	1.6	-0.3	0.1	1.5	0.4	1.1
Supplements: Calcium	0.9	0.9	3.2	-0.4	-0.1	-1.1	1.0	-1.8	-0.7	0.2	1.3	0.8
Ovarian Cancer	0.8	1.1	2.8	0.4	-1.6	-0.4	-1.1	1.2	-0.5	-0.8	-1.0	-1.7
Coronary Artery Disease (CAD)	0.8	1.0	2.1	-1.2	-0.5	-1.4	-0.6	-1.2	-1.3	-1.0	-0.6	-0.5
Average weekly spirits intake	0.8	1.0	3.3	-0.4	-0.6	0.7	0.4	-1.4	-0.4	-0.0	1.6	1.8
Sensitivity / hurt feelings	0.8	1.4	3.7	0.8	-0.9	-1.2	-1.9	1.9	0.0	-1.3	-0.7	-0.4
Ever used hormone-replacement therapy (HRT)	0.8	1.1	3.1	-1.8	-0.4	-1.4	-0.6	-1.4	0.6	-0.5	1.2	0.4
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.5	0.8	0.5	0.7	1.4	0.1	0.7	1.6	-1.1	-0.3
Mouth/teeth dental problems	0.8	1.2	3.9	-0.7	-1.2	-0.7	-1.7	2.0	0.0	-1.1	0.1	-0.9
Worrier / anxious feelings	0.8	1.4	4.0	-0.9	-0.9	-1.8	-1.1	2.0	0.2	-1.5	0.6	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	3.6	-1.5	-0.9	-1.9	-0.6	0.3	0.5	-0.8	0.9	0.6
Medication: Lansoprazole	0.8	0.9	2.2	-1.5	-0.7	-0.7	-1.0	-0.4	-1.3	-1.3	0.1	-0.4
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	2.2	0.7	1.3	1.5	1.3	0.3	0.6	1.4	-0.7	0.4
Number of children fathered	0.8	0.9	5.8	-2.4	0.2	0.4	-0.4	-0.6	-0.6	-0.9	0.3	0.4
Pulse wave peak to peak time	0.8	0.9	2.0	-1.1	-1.3	-1.4	-0.6	-0.2	-0.5	-1.1	1.1	0.7
Pulse rate, automated reading	0.8	2.5	5.2	-0.6	-2.1	-1.8	-2.3	-0.9	-1.6	-2.2	-0.5	-1.3
Suffer from ‘nerves’	0.8	1.2	4.7	0.1	-0.9	-2.2	-1.4	0.9	0.5	-1.3	0.5	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	2.2	-0.8	-1.5	-0.7	-1.0	1.3	-0.2	-1.2	-0.1	0.0
Average weekly champagne plus white wine intake	0.8	1.1	2.8	1.0	0.5	0.8	0.9	-1.3	0.2	1.0	1.4	1.7
Mother’s age at death	0.8	1.0	4.1	-0.4	-0.4	-0.3	0.5	-2.0	-1.9	0.7	-0.1	0.6
Financial situation satisfaction	0.8	0.9	4.0	-0.1	0.5	-0.8	0.5	-0.9	0.4	0.1	2.0	1.6
Leg fat percentage (left)	0.8	2.7	5.6	-0.3	2.1	2.4	1.6	-0.3	2.1	1.7	1.2	1.7
Cholesterol lowering medication	0.8	1.2	3.4	-1.4	-0.9	-1.0	-0.9	-1.9	-1.1	-0.3	0.3	1.1
Bipolar Disorder (2018)	0.7	1.1	4.3	-0.8	0.0	-0.5	0.8	-2.1	-1.8	0.9	-0.3	0.7
Breast Cancer	0.7	1.6	3.8	1.6	0.0	-0.3	0.8	0.5	1.8	1.2	2.0	1.5
Prostate Cancer	0.7	0.9	4.2	-0.2	0.1	-0.5	0.2	-2.0	-0.8	0.1	1.4	1.0
Age at First Birth	0.7	1.0	2.8	1.4	-1.0	-1.7	-0.4	-0.7	-1.2	-0.4	1.0	-0.1
Mean Putamen Volume	0.7	0.8	2.8	-0.9	0.4	0.2	-0.0	-1.4	0.3	-0.0	1.3	1.7
HDL Cholesterol	0.7	1.2	3.1	-1.1	-1.1	-0.6	0.3	-1.8	-0.9	-0.1	1.4	1.4
Cardiovascular Disease	0.7	2.3	7.0	-1.2	-1.2	-0.4	-0.8	-1.8	-2.6	-0.8	-2.3	-0.9
Respiratory disease	0.7	1.5	4.6	-1.4	-0.2	-1.6	0.4	-2.1	-0.9	-0.3	1.3	1.3
Chronotype (morning person)	0.7	1.7	3.7	1.9	1.2	1.6	1.0	1.0	0.8	1.9	-0.8	-0.7
Frequency of depressed mood in last 2 weeks	0.7	0.9	2.1	1.4	0.2	-1.4	0.8	-0.3	0.7	0.9	1.1	1.0
Systolic blood pressure, automated reading	0.7	1.9	4.2	-1.1	-1.2	-0.6	-1.6	-1.7	-2.0	-1.9	-0.5	-0.9
Nervous feelings	0.7	1.4	4.9	-0.6	-0.1	-2.2	-0.8	1.4	1.5	-0.7	1.1	0.7
Hair/balding pattern: Pattern 2	0.7	0.9	2.8	0.6	-0.1	-0.2	-1.4	1.7	-0.5	-1.3	-0.9	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	7.2	1.8	0.9	0.4	-1.1	2.7	1.1	-0.7	-0.3	-1.0
Qualifications: None of the above	0.7	1.5	3.8	0.1	1.7	1.2	1.9	-1.3	0.4	1.9	-0.0	-0.4
Mouth/teeth dental problems: Dentures	0.7	1.1	4.9	-0.2	0.3	-0.6	1.5	-2.2	0.0	0.6	0.9	1.1
Medication: Paracetamol	0.7	1.2	3.7	-1.1	0.6	-0.2	1.3	-1.9	1.1	0.9	0.9	1.0
Angina (self-reported)	0.7	0.9	3.4	-0.0	-0.8	-0.3	-0.3	1.2	-0.4	-0.8	-1.8	-1.4
Medication: Omeprazole	0.7	0.8	2.0	-1.1	-1.4	-1.4	-1.2	-0.5	-0.7	-0.3	-0.3	-0.2
Heart disease (mother)	0.7	0.8	2.3	1.5	-0.1	0.9	0.8	-0.4	-1.2	1.2	0.0	0.2
Medication for cholesterol	0.7	1.1	4.2	2.0	0.3	0.5	0.1	1.6	-0.2	-0.6	-0.7	-1.4
Medication: Aspirin	0.7	0.9	2.5	0.0	-0.3	1.5	-0.5	1.5	-0.1	0.2	-1.6	-0.9
Medication: Blood pressure	0.7	1.2	3.8	-1.8	-1.1	-1.0	-0.6	-2.0	-0.7	-0.3	0.1	0.9
Unable to work because of sickness or disability	0.7	1.0	5.0	-0.8	-0.4	0.7	0.1	0.1	-0.8	0.0	-2.2	-1.3
Vascular/heart problems diagnosed by doctor	0.7	1.9	6.4	1.2	1.5	0.6	0.6	2.5	2.2	0.3	1.2	0.4
Depression (Nagel 2018)	0.6	0.9	2.6	-1.2	-1.0	-1.6	-0.4	-0.6	0.4	-0.1	1.3	0.6
Rheumatoid Arthritis	0.6	0.8	1.8	-0.8	-0.9	-0.6	-1.1	-0.2	-1.3	-1.0	-0.5	-1.2
Angina	0.6	0.8	2.9	-0.1	-1.0	-0.3	-0.2	0.9	-0.5	-0.7	-1.7	-1.2
Pack years adult smoking proportion	0.6	0.9	3.5	-1.9	-0.0	0.5	0.3	-1.2	-0.4	0.9	-1.4	-0.6
Townsend deprivation index at recruitment	0.6	0.8	5.2	2.3	0.6	-0.0	0.5	-0.8	0.0	0.8	0.4	0.3
High blood pressure	0.6	1.7	8.0	-1.2	-1.2	-0.7	-0.4	-2.8	-1.9	-0.3	-0.5	0.0
Pain all over the body in last month	0.6	0.6	3.4	0.1	0.9	1.8	0.1	0.5	0.5	-0.2	-0.9	0.1
Impedance of arm (right)	0.6	3.0	8.1	-2.5	-2.8	-2.7	-0.3	-1.5	-1.3	-1.3	-0.4	0.1
Number of live births	0.6	0.9	4.5	-0.8	-0.9	-2.1	-0.4	-0.8	-0.5	-0.2	1.1	0.2
Happiness	0.6	0.7	1.7	-1.0	-0.4	-1.0	0.1	-1.1	-0.8	0.1	1.3	0.8
Ever highly irritable/argumentative for 2 days	0.6	0.7	3.5	-0.3	-0.2	-0.1	-0.5	1.9	-0.3	-0.3	-1.3	-0.7
Glaucoma (self-reported)	0.6	0.7	3.9	-0.9	-0.2	0.3	0.1	-0.6	-0.4	0.1	2.0	0.8
Medication: Amlodipine	0.6	0.9	2.1	-0.1	1.4	0.8	1.1	-0.4	1.0	0.6	1.3	0.9
Leg fat percentage (right)	0.6	2.2	5.2	-0.4	1.9	2.3	1.4	-0.2	1.9	1.5	1.2	1.4
Illnesses of siblings: Diabetes	0.6	0.8	2.7	-0.1	0.8	0.0	0.9	-1.6	-0.8	0.9	0.9	1.0
Smoking status: Previous	0.6	0.9	1.9	0.9	0.5	0.6	1.2	0.2	0.7	1.0	1.3	1.4
Mineral and other dietary supplements	0.6	0.8	1.8	1.3	0.4	0.8	0.7	1.3	0.3	0.2	-1.4	-0.6
Osteoporosis (self-reported)	0.6	0.7	1.3	0.8	0.9	-0.2	1.0	-1.1	-0.2	0.9	1.0	0.9
Ever smoked	0.6	1.1	4.5	-0.1	-0.1	0.4	1.0	-1.0	-0.5	0.4	1.6	2.1
Heart disease (siblings)	0.6	0.7	2.1	1.2	1.5	1.1	0.7	-0.1	0.5	0.4	-0.3	0.7
Pack years of smoking	0.6	0.8	3.0	-1.7	0.0	0.5	0.3	-1.2	-0.5	0.8	-1.1	-0.7
Bipolar Disorder or Schizophrenia	0.5	1.2	4.5	0.3	-0.1	-0.5	0.5	-2.1	-1.7	0.8	-1.5	-0.6
Crohns Disease (2012)	0.5	0.7	4.8	0.5	0.7	-0.4	0.7	0.5	0.0	0.2	-0.3	-2.2
Lupus	0.5	0.7	3.3	-0.2	-0.5	-0.8	0.2	0.7	-0.2	0.3	-1.8	-1.4
Blood Red Count	0.5	4.5	10.9	-1.7	1.1	1.2	2.9	-3.3	1.2	2.3	2.0	2.2
Systolic Blood Pressure	0.5	2.7	4.9	-1.7	-2.2	-1.1	-1.7	-1.6	-2.1	-2.0	-0.9	-1.0
Hand grip strength (left)	0.5	1.2	7.1	1.2	0.1	1.1	-0.0	2.7	0.6	-0.4	-0.5	-0.4
Fed-up feelings	0.5	0.9	3.3	1.8	0.5	-0.5	0.9	1.0	1.3	0.3	0.3	0.2
Multivitamins +/- minerals	0.5	0.6	1.7	-1.3	-0.3	-0.9	-0.4	-0.5	0.4	0.2	1.2	0.7
Supplements: Glucosamine	0.5	0.6	2.3	0.4	-0.4	-0.8	-0.9	-0.8	-0.4	-0.8	1.5	0.3
Allergy	0.5	1.2	5.6	0.7	-0.9	0.4	-1.1	2.4	0.4	-1.0	-0.4	-1.1
Medication: Cholesterol lowering	0.5	0.8	2.8	-0.6	0.7	1.7	1.4	-0.2	-0.3	1.2	-0.5	0.3
Birth weight of first child	0.5	1.0	5.7	0.3	1.0	0.5	-0.3	2.4	0.8	-0.1	-0.1	-1.0
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	2.0	-0.6	-1.0	-1.0	-0.7	-0.8	-0.4	-0.6	0.8	1.4
Blood clot in the leg (DVT)	0.5	0.6	1.6	0.8	1.3	0.9	0.7	0.2	-0.1	0.5	-1.2	-0.7
Headache pain in last month	0.5	0.9	2.5	-0.6	1.0	-0.0	1.6	-0.2	1.5	1.3	-0.0	0.7
Chronic bronchitis/emphysema (mother)	0.5	0.5	1.4	-0.8	0.1	0.8	1.2	-0.2	0.8	0.4	0.3	1.0
Exposure to tobacco smoke outside home	0.5	0.7	2.6	-1.6	-0.6	-0.4	-0.7	-0.6	-0.3	-0.5	1.0	1.1
Age at first live birth	0.5	0.9	3.5	0.3	1.2	1.9	0.5	0.4	-0.6	0.2	-1.0	-1.0
Qualifications: College or University degree	0.5	1.6	7.1	0.9	-0.6	-0.3	-1.7	2.7	-0.2	-1.0	-1.2	-1.1
Migraine (self-reported)	0.5	0.7	2.0	-0.7	-0.5	-0.7	-0.4	1.4	0.3	-0.4	-1.0	-1.1
Mean time to correctly identify matches	0.5	0.9	1.7	0.7	1.3	0.3	1.2	0.4	1.3	1.0	0.8	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.6	-1.2	-0.4	-0.7	-0.0	-0.2	0.3	-0.2	1.2	1.1
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.5	-0.5	0.6	0.2	0.7	-1.1	0.5	0.1	1.2	1.2
Long-standing illness, disability or infirmity	0.5	0.7	3.2	-0.8	0.5	0.0	0.7	-1.8	-0.3	0.7	0.0	1.2
Osteoarthritis (self-reported)	0.5	0.6	1.2	-0.7	-1.1	-0.7	-1.0	-0.8	-0.6	-1.0	0.5	0.0
Illnesses of father: None of the above (group 1)	0.5	0.6	1.8	-1.3	-0.1	-1.2	-1.1	-0.5	-0.7	-0.6	0.3	-0.2
Hearing aid user	0.5	0.5	2.1	-0.8	-0.1	-0.2	-0.4	-1.1	-0.1	-0.5	1.5	0.4
Basal cell carcinoma (self-reported)	0.5	0.6	1.5	-0.7	-1.2	-0.7	-1.0	-0.3	-0.4	-1.2	-0.2	-0.4
Schizophrenia (2018)	0.4	0.8	2.9	1.0	-0.2	-0.3	-0.0	-1.0	-0.8	0.3	-1.7	-1.2
Alzheimer’s Disease (in father)	0.4	0.4	1.8	0.4	0.0	-0.9	0.4	-0.1	0.3	-0.1	1.4	0.8
Schizophrenia (2014)	0.4	0.8	3.8	-0.2	0.2	-0.0	0.9	-2.0	-0.7	0.9	-1.0	-0.1
Blood Platelet Count	0.4	4.2	10.4	-2.6	-0.6	-1.9	0.7	-2.8	0.6	0.5	3.2	2.7
Hypothyroidism (self reported)	0.4	1.0	2.9	-1.2	0.3	-0.4	0.6	-1.5	-0.2	0.5	1.7	1.3
Lung FEV1/FVC ratio	0.4	2.2	9.2	-0.1	0.4	-0.9	-0.7	-2.1	-0.1	0.5	3.0	2.2
Supplements: Zinc	0.4	0.5	0.8	-0.9	-0.7	-0.8	-0.8	-0.1	0.2	-0.8	0.9	-0.5
Hand grip strength (right)	0.4	1.0	3.8	0.5	0.8	1.7	0.6	1.9	0.8	0.0	-0.6	-0.1
Taking other prescription medications	0.4	0.6	3.2	-1.8	0.4	-0.7	-0.2	-0.6	0.2	0.1	0.8	0.8
High blood pressure (mother)	0.4	0.6	2.0	0.2	-1.3	-0.1	-0.9	0.7	-0.5	-0.0	-1.4	-0.7
Number of incorrect matches in round	0.4	0.7	2.5	0.1	1.4	0.9	1.6	-0.5	0.7	0.5	-0.1	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.4	-0.5	0.4	-0.5	0.9	0.4	1.2	0.9	1.1	0.7
Had menopause	0.4	0.5	1.8	0.3	-0.3	-1.0	-1.0	-0.0	-0.4	-0.5	0.2	-1.3
Illnesses of siblings	0.4	0.5	1.7	-0.5	-1.3	-1.3	-0.8	0.0	-0.2	-0.2	0.3	-0.3
Neuroticism score	0.4	0.8	4.6	0.5	0.3	-0.7	-0.3	2.1	1.2	-0.4	-0.4	-0.4
Falls in the last year	0.4	0.5	1.8	0.6	0.9	0.8	0.8	0.5	1.3	0.4	-0.2	0.3
Standing height	0.4	4.1	8.7	2.2	3.0	2.9	1.0	2.5	1.8	0.9	-2.0	-0.1
Hair/balding pattern: Pattern 4	0.4	0.9	3.7	0.2	-0.4	-0.3	0.4	-1.3	0.1	-0.5	1.9	1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.8	0.9	-0.4	-0.1	-0.7	1.3	-0.1	-0.5	-0.6	-1.1
Medication: Allopurinol	0.4	0.5	2.4	-0.2	-0.4	-0.2	-0.3	-0.6	-1.6	-0.8	-0.8	0.5
Number of full sisters	0.4	0.5	1.1	0.5	-0.8	-1.1	-0.4	-0.3	-1.0	-0.1	-0.9	-0.8
Age at last live birth	0.4	0.6	1.3	0.6	0.2	1.0	-0.2	-0.1	-1.0	-0.4	-1.2	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.7	2.9	-0.3	1.7	0.3	0.9	-0.7	0.4	1.1	0.5	0.9
Ever had bowel cancer screening	0.4	0.5	3.0	0.0	0.0	-0.1	0.1	-0.5	0.8	0.0	1.7	0.6
Breast cancer (self-reported)	0.4	0.5	1.0	-0.7	1.0	0.7	1.0	0.2	0.7	0.8	0.2	-0.1
Wears glasses or contact lenses	0.4	0.5	1.8	0.5	-0.4	-0.4	-0.8	-0.7	-1.3	-0.4	-0.4	-0.6
High cholesterol (Self-reported)	0.4	0.6	2.9	-0.8	-0.7	-0.1	-0.3	-1.0	-1.7	-0.1	-0.8	-0.1
Fractured/broken bones in last 5 years	0.4	0.5	2.1	0.9	-0.1	0.5	-0.8	-0.1	-0.3	-0.5	-1.4	-0.9
Commuting to job workplace: Cycle	0.4	0.4	1.6	-0.1	0.3	-0.2	1.3	-0.3	-0.0	1.2	0.3	0.8
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.4	-0.9	-1.0	-1.2	-0.7	-0.9	-0.6	-0.1	0.0	0.3
Depressed Affect (Nagel 2018)	0.3	0.6	1.0	-0.1	-0.7	-1.0	-0.9	0.9	-0.1	-0.8	-0.7	-1.0
Crohns Disease (2017)	0.3	0.6	1.8	-1.1	1.1	-0.6	0.7	-0.3	0.2	0.4	0.5	-1.3
Height	0.3	4.9	12.5	3.1	2.8	3.5	1.0	2.0	1.7	1.1	-2.1	0.5
Tanning	0.3	3.7	8.2	-1.9	-2.9	-2.6	-2.5	-0.9	-0.9	-2.4	0.7	0.9
Number of treatments/medications taken	0.3	0.6	3.1	-1.8	0.1	-0.5	-0.4	-1.4	-0.2	0.3	-0.0	-0.0
Medication for hormone replacement therapy	0.3	0.3	2.5	-0.4	0.2	-0.2	0.1	0.4	1.6	0.4	0.2	0.1
Vitamin and mineral supplements	0.3	0.4	0.8	0.9	-0.4	-0.2	-0.6	0.7	-0.5	-0.6	-0.5	-0.7
Medication: Metformin	0.3	0.4	1.2	-0.7	0.3	0.9	0.6	0.1	0.4	0.2	0.4	1.1
Serious illness, injury or assault to yourself	0.3	0.4	1.1	0.4	0.1	-0.0	0.3	-0.4	0.7	1.1	0.8	0.8
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.7	-0.7	-0.6	-0.6	-0.5	0.3	0.2	-0.7	0.8	0.4
Past tobacco smoking	0.3	0.5	2.3	-0.1	0.3	0.0	-0.5	0.1	0.1	-0.0	-1.5	-1.4
Alcohol usually taken with meals	0.3	0.5	1.8	-0.6	-0.6	-0.7	-0.4	-1.4	-0.9	-0.5	0.7	-0.3
Time employed in main current job	0.3	0.4	1.9	-0.3	0.4	1.4	0.7	-0.3	0.2	0.6	0.2	0.5
Qualifications: A levels/AS levels or equivalent	0.3	0.8	3.3	0.7	-0.7	0.5	-0.8	-0.6	-1.8	-0.3	-1.1	-0.3
Illnesses of mother	0.3	0.4	1.2	-0.7	1.1	-0.2	-0.1	-0.7	0.2	-1.0	0.5	-0.3
Length of working week for main job	0.3	0.3	1.0	-1.0	-0.1	-0.0	0.1	-0.9	-0.3	0.6	0.5	0.3
Peak expiratory flow (PEF)	0.3	0.8	2.5	-1.1	1.6	1.0	-0.5	1.0	0.7	-0.0	0.3	0.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	1.2	0.7	-0.0	-0.9	-0.4	1.1	1.1	-0.3	1.0	0.2
Gout (self-reported)	0.3	0.4	1.1	-0.3	-0.3	-0.7	-0.9	0.5	-0.7	-1.0	-0.5	0.4
Birth weight	0.3	0.7	2.8	-0.1	1.7	0.5	1.0	0.2	1.0	0.6	0.7	0.5
Emphysema/chronic bronchitis	0.3	0.3	1.1	0.4	-0.3	0.2	-0.1	-0.8	-1.1	0.4	0.2	-0.7
Neck or shoulder pain in last month	0.3	0.4	0.8	-0.2	-0.9	-0.9	-0.4	-0.4	-0.8	-0.9	-0.0	0.4
Medication: Blood pressure	0.3	0.6	2.0	0.0	0.7	1.4	0.9	-0.9	-0.5	0.8	-0.4	-0.2
Comparative height size at age 10	0.3	1.9	6.2	0.8	2.5	1.9	1.4	0.5	1.1	1.1	0.4	1.3
Miserableness	0.3	0.4	0.9	0.1	-0.8	-0.9	-1.0	0.9	-0.3	-0.6	-0.3	-0.4
Medication: Atorvastatin	0.3	0.4	1.4	0.7	-0.1	0.5	0.4	1.2	0.4	0.1	-0.9	-0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.8	-0.7	-0.7	-0.2	0.9	-0.8	-0.6	0.6	-0.1	0.3
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.5	0.7	0.9	0.5	0.4	0.1	-0.5	0.2	-1.2	-0.7
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.0	1.4	-0.8	0.0	-0.8	1.3	-0.2	-0.8	-0.6	-0.2
LDL Cholesterol	0.2	0.3	0.9	-0.2	0.1	0.8	0.4	-0.1	0.9	0.3	-0.1	0.8
Triglycerides	0.2	0.3	1.0	0.6	0.3	0.3	0.3	0.5	0.9	0.4	-1.0	0.4
Hair Pigment	0.2	6.1	31.8	1.9	2.2	-0.2	-0.2	5.6	3.4	-0.2	-0.6	-1.7
Stomach or abdominal pain in last month	0.2	0.2	1.3	-1.1	-0.4	-0.0	0.0	0.4	-0.3	-0.2	-0.4	0.1
Medication: Atenolol	0.2	0.3	0.8	-0.9	0.0	0.4	0.7	-0.1	0.2	0.9	0.4	0.6
Chronic bronchitis/emphysema (father)	0.2	0.2	0.8	-0.0	-0.8	-0.5	0.2	-0.2	-0.1	-0.4	0.1	0.9
Heart attack	0.2	0.3	0.6	-0.6	-0.7	-0.2	0.8	-0.7	-0.7	0.5	-0.3	0.2
Diabetes (self-reported)	0.2	0.3	0.6	-0.6	0.2	0.7	-0.2	0.8	0.6	-0.3	-0.6	-0.3
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.0	-0.4	0.3	-0.3	0.6	-1.0	-0.2	0.6	0.5	0.3
Alcohol intake versus 10 years previously	0.2	0.3	0.9	0.8	-0.2	-0.1	-0.4	0.2	-0.2	-0.9	-1.0	-0.7
Father’s age at death	0.2	0.3	1.4	-0.0	-0.4	0.3	0.1	-0.1	0.6	0.2	1.2	0.5
Prospective memory result	0.2	0.3	1.3	0.3	0.1	1.1	0.7	-0.3	-0.2	0.1	-0.5	-0.0
Breastfed as a baby	0.2	0.2	1.1	0.5	-1.1	0.1	-0.6	0.2	-0.3	-0.4	-0.4	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.8	0.1	-0.4	-0.7	0.3	0.5	0.2	-0.2	0.6	0.9
High blood pressure (siblings)	0.2	0.2	1.1	-0.1	0.4	1.1	0.5	-0.4	-0.5	-0.1	0.4	0.2
Wheeze or whistling in the chest in last year	0.2	0.4	1.1	-0.1	-1.0	-0.9	-0.6	-0.3	-0.5	-0.7	-0.0	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.6	-0.1	-0.6	-0.3	-0.2	0.5	-0.2	-0.6	-0.5	-0.8
Eye problems/disorders: None of the above	0.2	0.2	0.8	0.9	0.3	0.2	0.1	0.5	0.6	-0.3	-0.5	-0.3
Medication for pain relief, constipation, heartburn	0.2	0.4	1.3	0.2	-0.1	-0.0	-1.0	-0.3	-1.1	-0.6	0.7	-0.2
Chest pain or discomfort	0.2	0.3	1.3	-1.1	-0.6	0.2	0.2	0.2	-0.7	-0.4	-0.0	0.5
Mood swings	0.2	0.3	1.4	-0.0	0.7	-0.2	-0.1	1.2	0.3	-0.2	-0.8	-0.4
Loneliness, isolation	0.2	0.3	1.4	1.2	0.5	-0.5	0.2	-0.3	0.3	-0.0	-0.8	-0.3
Friendships satisfaction	0.2	0.2	0.5	0.4	0.7	0.2	-0.7	0.2	-0.4	0.1	0.6	0.3
Back pain experienced in last month	0.2	0.2	0.5	0.6	0.7	0.5	0.2	-0.2	-0.4	0.5	-0.7	-0.3
Risk taking	0.2	0.2	1.0	0.3	-0.3	-0.2	1.0	-0.5	0.4	0.0	-0.1	0.7
Age started oral contraceptive pill	0.2	0.2	0.8	0.5	0.9	0.5	0.1	0.0	0.5	0.3	-0.1	-0.5
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.5	1.2	-0.0	0.7	-0.4	0.5	-0.1	-0.3	-0.3	0.2
HbA1C	0.1	0.1	0.4	0.6	-0.3	0.2	-0.2	-0.2	0.5	-0.3	-0.4	-0.1
Primary Biliary Cirrhosis	0.1	0.1	0.4	-0.2	-0.1	0.2	0.2	0.2	0.5	-0.2	-0.6	-0.0
Blood Eosinophil Count	0.1	0.5	1.4	-0.4	1.2	0.8	0.7	0.9	-0.0	0.1	-1.1	-0.4
Blood White Count	0.1	0.8	3.6	-1.9	0.1	0.9	0.6	0.7	1.0	0.4	0.9	0.3
Waist Hip Ratio (WHR)	0.1	0.5	1.1	0.3	0.8	0.8	0.5	-0.4	0.5	1.1	-0.7	-0.8
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.6	0.2	0.3	0.7	0.1	0.8	0.5	-0.1	-0.3	0.2
Relative age of first facial hair	0.1	0.3	1.2	-0.0	0.3	-0.1	0.0	1.1	1.0	0.2	-0.5	0.2
Qualifications: CSEs or equivalent	0.1	0.2	0.6	0.3	0.8	0.2	0.4	-0.5	0.7	0.1	-0.2	0.0
Fluid intelligence score	0.1	0.3	1.3	1.1	0.1	0.6	0.3	-0.3	0.5	0.2	0.4	0.6
Noisy workplace	0.1	0.1	0.5	0.1	-0.0	-0.2	-0.3	-0.1	-0.7	-0.5	0.2	-0.4
Tense / ‘highly strung’	0.1	0.2	0.7	-0.8	-0.5	-0.7	-0.1	0.3	0.3	-0.1	0.6	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.3	-0.6	-0.2	-0.2	0.4	-0.4	0.6	-0.1	0.1	-0.1
Diabetes diagnosed by doctor	0.1	0.1	0.4	-0.4	0.5	0.6	0.2	0.0	0.5	0.2	0.3	0.4
Eye problems/disorders: Cataract	0.1	0.1	0.3	0.1	-0.0	-0.3	-0.4	0.5	-0.5	-0.2	0.4	-0.1
Average weekly beer plus cider intake	0.1	0.2	0.7	-0.1	0.4	0.4	0.5	0.1	0.3	0.0	0.3	0.9
Pain experienced in last month	0.1	0.2	1.0	0.4	-0.1	0.8	0.4	1.0	0.1	0.1	-0.2	-0.3
Overall health rating	0.0	0.1	0.6	-0.7	-0.1	-0.3	-0.1	-0.4	-0.1	-0.1	0.2	-0.0

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