[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr12:27,587,038-29,432,481

Best TWAS P=2.53e-09 · Best GWAS P=2.84e-10 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Cells Transformed fibroblasts	RP11-967K21.1	0.07	0.07	lasso	2	0.07	3.7e-06	-5.9	6.0	2.5e-09	-0.96	0.05	0.95	TRUE
3	GTEx	Heart Atrial Appendage	RP11-967K21.1	0.08	0.09	lasso	1	0.08	2.3e-04	-5.9	5.9	4.3e-09	-0.91	0.04	0.92	FALSE
1	GTEx	Cells Transformed fibroblasts	CCDC91	0.10	0.10	lasso	5	0.09	5.5e-07	-5.6	-5.8	8.2e-09	0.85	0.11	0.89	FALSE
5	GTEx	Skin Not Sun Exposed Suprapubic	CCDC91	0.26	0.05	lasso	15	0.04	4.1e-03	-6.3	-5.6	2.3e-08	0.87	0.03	0.97	FALSE
6	GTEx	Skin Sun Exposed Lower leg	CCDC91	0.09	0.01	enet	8	0.01	2.6e-02	-5.9	-5.6	2.7e-08	0.85	0.07	0.88	FALSE
8	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CCDC91	0.09	0.11	lasso	2	0.12	2.3e-05	-5.4	-5.4	5.8e-08	0.91	0.07	0.91	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	CCDC91	0.04	0.04	lasso	3	0.03	1.8e-06	-5.4	-5.4	8.3e-08	0.94	0.18	0.82	FALSE
4	GTEx	Muscle Skeletal	RP11-967K21.1	0.04	0.01	lasso	9	0.00	2.9e-01	-5.5	5.1	3.1e-07	-0.90	0.06	0.80	FALSE