[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr12:101,575,652-103,148,974

Best TWAS P=2.83e-08 · Best GWAS P=2.67e-12 conditioned to 5.41e-12

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	YFS	Blood	DRAM1	0.33	0.13	enet	101	0.19	1.6e-58	5.6	5.5	2.8e-08	0.10	0.01	0.99	TRUE
8	The Cancer Genome Atlas	Stomach Adenocarcinoma	CCDC53	0.04	0.07	lasso	4	0.06	2.1e-05	5.5	-5.4	5.3e-08	0.13	0.02	0.98	TRUE
2	GTEx	Cells Transformed fibroblasts	CCDC53	0.10	0.18	lasso	1	0.17	1.5e-12	5.4	-5.4	5.6e-08	0.13	0.04	0.96	FALSE
4	GTEx	Spleen	CCDC53	0.25	0.19	lasso	11	0.16	5.8e-05	5.5	-5.4	7.6e-08	0.12	0.06	0.88	FALSE
5	METSIM	Adipose	DRAM1	0.12	0.03	enet	24	0.08	1.1e-12	3.5	5.3	1.2e-07	0.06	0.03	0.97	FALSE
7	The Cancer Genome Atlas	Colon Adenocarcinoma	CCDC53	0.07	0.07	blup	55	0.06	1.3e-04	4.7	-5.2	1.6e-07	0.09	0.05	0.94	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CCDC53	0.21	0.15	blup	448	0.19	2.4e-22	3.9	-5.2	2.1e-07	0.08	0.27	0.73	FALSE
3	GTEx	Heart Left Ventricle	CCDC53	0.14	0.20	lasso	4	0.18	9.6e-10	5.5	-5.2	2.4e-07	0.14	0.04	0.96	FALSE