[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr14:90,643,934-94,495,324

Best TWAS P=4.26e-12 · Best GWAS P=5.66e-12 conditioned to 0.0799

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex BTBD7 0.04 0.04 lasso 2 0.03 1.8e-04 -4.8 5.2 2.3e-07 -0.04 0.47 0.50 FALSE
2 GTEx Cells Transformed fibroblasts BTBD7 0.16 0.01 lasso 8 0.04 3.6e-04 -6.2 6.1 8.8e-10 -0.02 0.10 0.88 FALSE
3 GTEx Cells Transformed fibroblasts RPS6KA5 0.08 0.07 lasso 2 0.06 5.3e-05 -6.4 6.6 5.6e-11 -0.89 0.04 0.95 FALSE
4 GTEx Colon Sigmoid RIN3 0.24 0.17 lasso 6 0.11 9.3e-05 6.7 -6.6 5.4e-11 0.03 0.00 0.99 TRUE
5 GTEx Colon Sigmoid RPS6KA5 0.16 0.09 lasso 5 0.08 7.1e-04 -5.2 -5.3 1.0e-07 0.81 0.04 0.89 FALSE
6 GTEx Esophagus Muscularis RIN3 0.17 0.05 lasso 6 0.06 1.6e-04 5.4 -5.5 4.1e-08 0.00 0.05 0.82 FALSE
7 GTEx Spleen C14orf159 0.30 0.21 lasso 5 0.21 3.6e-06 -5.9 6.9 4.3e-12 -0.81 0.08 0.43 TRUE
8 GTEx Testis BTBD7 0.19 0.00 enet 45 0.01 9.5e-02 -4.6 5.7 1.4e-08 -0.01 0.05 0.86 FALSE
9 METSIM Adipose C14orf159 0.04 0.00 blup 464 0.01 4.0e-03 -5.1 5.5 4.2e-08 -0.70 0.07 0.78 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma BTBD7 0.02 0.01 blup 72 0.02 6.8e-03 -5.9 5.4 7.8e-08 -0.01 0.01 0.87 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors BTBD7 0.11 0.03 blup 72 0.02 8.0e-02 -6.2 6.2 5.4e-10 -0.01 0.02 0.82 TRUE