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Leg fat-free mass (right)
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chr15:65,974,936-68,789,191
Best TWAS P=2.58e-08 · Best GWAS P=5.82e-12 conditioned to 0.000105
66M
66.5M
67M
67.5M
68M
68.5M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Visceral Omentum
RPL9P25
0.26
0.02
enet
27
0.07
1.3e-04
-2.4
-5.6
2.6e-08
0.05
0.72
0.02
TRUE
3
GTEx
Muscle Skeletal
MAP2K5
0.08
0.03
lasso
6
0.05
1.9e-05
4.5
5.5
3.6e-08
-0.69
0.37
0.63
TRUE
2
GTEx
Breast Mammary Tissue
MAP2K5
0.14
0.07
lasso
5
0.09
2.8e-05
-5.5
5.4
7.0e-08
-0.87
0.03
0.97
FALSE
4
METSIM
Adipose
MAP2K5
0.07
0.05
enet
19
0.06
2.8e-09
-5.4
5.2
2.5e-07
-0.85
0.12
0.88
FALSE