Best TWAS P=2.58e-08 · Best GWAS P=5.82e-12 conditioned to 0.000105
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | RPL9P25 | 0.26 | 0.02 | enet | 27 | 0.07 | 1.3e-04 | -2.4 | -5.6 | 2.6e-08 | 0.05 | 0.72 | 0.02 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | MAP2K5 | 0.14 | 0.07 | lasso | 5 | 0.09 | 2.8e-05 | -5.5 | 5.4 | 7.0e-08 | -0.87 | 0.03 | 0.97 | FALSE |
| 3 | GTEx | Muscle Skeletal | MAP2K5 | 0.08 | 0.03 | lasso | 6 | 0.05 | 1.9e-05 | 4.5 | 5.5 | 3.6e-08 | -0.69 | 0.37 | 0.63 | TRUE |
| 4 | METSIM | Adipose | MAP2K5 | 0.07 | 0.05 | enet | 19 | 0.06 | 2.8e-09 | -5.4 | 5.2 | 2.5e-07 | -0.85 | 0.12 | 0.88 | FALSE |