Best TWAS P=6.71e-09 · Best GWAS P=1.19e-11 conditioned to 0.000439
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Lung Adenocarcinoma | FAM108C1 | 0.05 | 0.04 | lasso | 3 | 0.04 | 5.6e-06 | 5.8 | -5.8 | 6.7e-09 | -0.86 | 0.07 | 0.93 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM108C1 | 0.07 | 0.02 | lasso | 2 | 0.02 | 1.7e-03 | -3.8 | -5.3 | 1.2e-07 | -0.82 | 0.03 | 0.60 | FALSE |