[Hub]/) : Traits : Leg fat-free mass (right) :

chr2:168,949,234-170,419,444

Best TWAS P=3.05e-15 · Best GWAS P=1.63e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NOSTRIN 0.14 0.13 lasso 4 0.12 1.9e-14 -7.4 7.9 3.0e-15 -0.97 0.00 1.00 TRUE
2 GTEx Adrenal Gland NOSTRIN 0.21 0.09 lasso 4 0.09 4.1e-04 5.6 5.7 1.3e-08 -0.40 0.16 0.70 FALSE
3 GTEx Lung NOSTRIN 0.09 0.06 lasso 4 0.07 7.1e-06 7.1 6.4 1.4e-10 -0.39 0.02 0.98 FALSE
4 GTEx Pancreas NOSTRIN 0.30 0.12 enet 17 0.08 3.3e-04 -5.5 5.3 1.3e-07 -0.47 0.07 0.91 FALSE
5 GTEx Stomach NOSTRIN 0.15 0.04 enet 9 0.09 6.8e-05 7.1 7.2 4.2e-13 -0.58 0.02 0.97 FALSE
6 GTEx Testis NOSTRIN 0.43 0.17 enet 17 0.32 1.0e-14 -5.0 6.1 1.1e-09 -0.68 0.07 0.93 FALSE
7 METSIM Adipose NOSTRIN 0.07 0.09 lasso 6 0.08 1.6e-12 7.1 7.0 1.9e-12 -0.59 0.02 0.98 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma NOSTRIN 0.03 0.01 blup 55 0.02 9.5e-05 -5.3 5.8 5.4e-09 -0.37 0.01 0.97 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma G6PC2 0.32 0.07 blup 29 0.06 3.8e-04 -4.5 -6.3 3.5e-10 0.79 0.02 0.75 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma G6PC2 0.47 0.23 enet 8 0.28 4.4e-32 -4.5 -5.5 4.2e-08 0.79 0.07 0.90 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NOSTRIN 0.12 0.13 lasso 7 0.14 4.5e-15 -5.3 6.0 1.8e-09 -0.43 0.01 0.99 FALSE
12 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma G6PC2 0.56 0.13 blup 29 0.16 2.1e-09 -4.5 -6.0 2.5e-09 0.75 0.03 0.95 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma NOSTRIN 0.08 0.01 enet 6 0.04 2.1e-05 5.2 5.9 2.9e-09 -0.32 0.01 0.96 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NOSTRIN 0.05 0.00 blup 55 0.01 1.1e-02 -5.3 5.6 1.7e-08 -0.38 0.01 0.69 FALSE
15 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma NOSTRIN 0.17 0.07 lasso 2 0.08 4.3e-04 4.8 5.4 7.5e-08 -0.44 0.02 0.92 FALSE