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Traits
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Traits
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Leg fat-free mass (right)
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chr2:217,456,567-219,320,207
Best TWAS P=1.07e-16 · Best GWAS P=1.32e-30 conditioned to 3.17e-10
217.5M
218M
218.5M
219M
0
5
10
15
20
25
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Thyroid Carcinoma
DIRC3
0.08
0.06
lasso
5
0.07
2.7e-07
-9.12
8.3
1.1e-16
-0.56
0.98
0.01
TRUE
1
ROSMAP
Brain Pre-frontal Cortex
DIRC3
0.12
0.07
bslmm
697
0.08
2.7e-10
-6.45
7.2
6.9e-13
0.00
1.00
0.00
TRUE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
DIRC3
0.12
0.01
blup
275
0.02
3.3e-03
-0.92
7.0
2.7e-12
-0.51
0.05
0.52
TRUE