[Hub]/) : Traits : Leg fat-free mass (right) :

chr3:87,495,550-88,911,119

Best TWAS P=4.12e-12 · Best GWAS P=2.79e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C3orf38 0.08 0.00 enet 14 0.04 2.3e-05 -5.9 -6.7 1.9e-11 0.63 0.05 0.92 FALSE
2 GTEx Adipose Visceral Omentum C3orf38 0.09 0.00 lasso 5 0.00 5.2e-01 -2.3 5.4 5.3e-08 -0.72 0.04 0.36 FALSE
3 GTEx Artery Aorta C3orf38 0.06 0.06 lasso 7 0.05 6.0e-04 -6.0 6.0 1.8e-09 -0.80 0.38 0.45 FALSE
4 GTEx Cells Transformed fibroblasts ZNF654 0.08 0.09 enet 6 0.10 3.1e-08 -6.9 -6.9 4.1e-12 0.99 0.00 1.00 TRUE
5 GTEx Esophagus Mucosa C3orf38 0.11 0.06 lasso 7 0.07 1.5e-05 -6.0 6.6 3.9e-11 -0.91 0.08 0.91 FALSE
6 GTEx Nerve Tibial C3orf38 0.09 0.05 lasso 4 0.04 6.3e-04 -6.0 6.0 1.5e-09 -0.80 0.43 0.42 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic ZNF654 0.09 0.01 lasso 7 0.06 2.7e-04 -6.0 -5.3 1.5e-07 0.74 0.10 0.28 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic C3orf38 0.09 0.07 lasso 6 0.04 2.8e-03 -5.8 5.7 1.5e-08 -0.78 0.32 0.30 FALSE
9 GTEx Testis C3orf38 0.11 0.01 enet 12 0.00 1.9e-01 -5.3 5.3 1.4e-07 -0.42 0.12 0.19 FALSE
10 GTEx Thyroid C3orf38 0.12 0.08 lasso 18 0.07 1.0e-05 -5.8 5.9 3.8e-09 -0.80 0.70 0.28 FALSE
11 GTEx Uterus ZNF654 0.29 -0.01 lasso 4 0.01 1.7e-01 -5.9 -5.2 1.8e-07 0.71 0.09 0.17 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma C3orf38 0.01 0.01 lasso 3 0.01 1.2e-03 -5.9 5.8 7.0e-09 -0.80 0.03 0.38 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C3orf38 0.02 0.01 blup 24 0.02 2.0e-03 -5.9 5.9 4.7e-09 -0.82 0.06 0.27 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf38 0.02 0.03 lasso 1 0.03 1.9e-04 -5.9 5.9 3.6e-09 -0.79 0.05 0.46 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma C3orf38 0.03 0.05 lasso 1 0.05 8.1e-06 -5.9 5.9 3.6e-09 -0.79 0.27 0.66 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma CGGBP1 0.30 0.07 enet 11 0.09 2.3e-09 -6.8 -5.5 3.1e-08 0.23 0.00 1.00 TRUE
17 The Cancer Genome Atlas Thyroid Carcinoma ZNF654 0.03 0.04 lasso 3 0.03 4.6e-04 -5.9 -6.0 2.2e-09 0.80 0.11 0.67 FALSE