[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr3:87,495,550-88,911,119

Best TWAS P=4.12e-12 · Best GWAS P=2.79e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Cells Transformed fibroblasts	ZNF654	0.08	0.09	enet	6	0.10	3.1e-08	-6.9	-6.9	4.1e-12	0.99	0.00	1.00	TRUE
16	The Cancer Genome Atlas	Thyroid Carcinoma	CGGBP1	0.30	0.07	enet	11	0.09	2.3e-09	-6.8	-5.5	3.1e-08	0.23	0.00	1.00	TRUE
1	CommonMind	Brain Pre-frontal Cortex	C3orf38	0.08	0.00	enet	14	0.04	2.3e-05	-5.9	-6.7	1.9e-11	0.63	0.05	0.92	FALSE
5	GTEx	Esophagus Mucosa	C3orf38	0.11	0.06	lasso	7	0.07	1.5e-05	-6.0	6.6	3.9e-11	-0.91	0.08	0.91	FALSE
6	GTEx	Nerve Tibial	C3orf38	0.09	0.05	lasso	4	0.04	6.3e-04	-6.0	6.0	1.5e-09	-0.80	0.43	0.42	FALSE
3	GTEx	Artery Aorta	C3orf38	0.06	0.06	lasso	7	0.05	6.0e-04	-6.0	6.0	1.8e-09	-0.80	0.38	0.45	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF654	0.03	0.04	lasso	3	0.03	4.6e-04	-5.9	-6.0	2.2e-09	0.80	0.11	0.67	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C3orf38	0.02	0.03	lasso	1	0.03	1.9e-04	-5.9	5.9	3.6e-09	-0.79	0.05	0.46	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	C3orf38	0.03	0.05	lasso	1	0.05	8.1e-06	-5.9	5.9	3.6e-09	-0.79	0.27	0.66	FALSE
10	GTEx	Thyroid	C3orf38	0.12	0.08	lasso	18	0.07	1.0e-05	-5.8	5.9	3.8e-09	-0.80	0.70	0.28	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C3orf38	0.02	0.01	blup	24	0.02	2.0e-03	-5.9	5.9	4.7e-09	-0.82	0.06	0.27	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	C3orf38	0.01	0.01	lasso	3	0.01	1.2e-03	-5.9	5.8	7.0e-09	-0.80	0.03	0.38	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	C3orf38	0.09	0.07	lasso	6	0.04	2.8e-03	-5.8	5.7	1.5e-08	-0.78	0.32	0.30	FALSE
2	GTEx	Adipose Visceral Omentum	C3orf38	0.09	0.00	lasso	5	0.00	5.2e-01	-2.3	5.4	5.3e-08	-0.72	0.04	0.36	FALSE
9	GTEx	Testis	C3orf38	0.11	0.01	enet	12	0.00	1.9e-01	-5.3	5.3	1.4e-07	-0.42	0.12	0.19	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	ZNF654	0.09	0.01	lasso	7	0.06	2.7e-04	-6.0	-5.3	1.5e-07	0.74	0.10	0.28	FALSE
11	GTEx	Uterus	ZNF654	0.29	-0.01	lasso	4	0.01	1.7e-01	-5.9	-5.2	1.8e-07	0.71	0.09	0.17	FALSE