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Leg fat-free mass (right)
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chr5:87,006,055-88,677,293
Best TWAS P=2.51e-10 · Best GWAS P=1.16e-13 conditioned to 9.04e-09
87M
87.2M
87.4M
87.6M
87.8M
88M
88.2M
88.4M
88.6M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
CTC-498M16.2
0.11
0.13
lasso
6
0.12
1.2e-14
-7.2
-6.3
2.5e-10
0.95
0.01
0.99
TRUE
1
ROSMAP
Brain Pre-frontal Cortex
LINC00461
0.10
0.07
lasso
2
0.05
4.5e-07
5.8
5.8
6.3e-09
0.06
0.99
0.01
TRUE