[Hub]/) : Traits : Leg fat-free mass (right) :

chr5:111,535,501-112,950,045

Best TWAS P=1.41e-09 · Best GWAS P=4.05e-09 conditioned to 0.0125

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum REEP5 0.09 0.05 lasso 5 0.02 4.9e-02 5.1 5.2 2.5e-07 -0.60 0.04 0.90 FALSE
2 GTEx Esophagus Gastroesophageal Junction REEP5 0.18 0.03 lasso 3 0.03 3.7e-02 5.3 5.3 1.3e-07 -0.61 0.03 0.88 FALSE
3 GTEx Esophagus Mucosa REEP5 0.19 0.10 lasso 5 0.09 1.5e-06 5.3 5.2 1.7e-07 -0.60 0.05 0.93 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic REEP5 0.11 0.10 lasso 7 0.10 6.3e-06 4.8 5.2 1.7e-07 -0.63 0.13 0.85 FALSE
5 GTEx Testis REEP5 0.22 0.14 lasso 5 0.14 6.6e-07 5.0 5.4 7.9e-08 -0.59 0.08 0.91 FALSE
6 NTR Blood REEP5 0.03 0.04 lasso 9 0.04 3.3e-12 5.8 6.0 1.4e-09 -0.66 0.01 0.99 TRUE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma APC 0.03 0.02 blup 77 0.02 5.2e-03 4.9 5.1 2.8e-07 -0.45 0.02 0.47 FALSE