[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr7:134,548,572-136,094,817

Best TWAS P=7.82e-09 · Best GWAS P=1.08e-08 conditioned to 0.051

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous C7orf73 0.23 0.14 lasso 7 0.18 9.5e-15 4.2 -5.3 9.1e-08 0.70 0.21 0.78 FALSE
2 GTEx Artery Coronary C7orf73 0.40 0.29 enet 18 0.30 1.3e-10 4.2 -5.4 8.5e-08 0.65 0.14 0.85 FALSE
3 GTEx Breast Mammary Tissue C7orf73 0.15 0.11 lasso 6 0.15 4.3e-08 4.1 -5.5 3.0e-08 0.69 0.06 0.94 FALSE
4 GTEx Breast Mammary Tissue (Male) C7orf73 0.24 0.08 lasso 8 0.14 3.5e-04 -5.7 -5.2 1.5e-07 0.81 0.01 0.79 FALSE
5 GTEx Colon Sigmoid C7orf73 0.25 0.22 lasso 2 0.21 6.1e-08 4.3 -5.1 2.9e-07 0.61 0.08 0.86 FALSE
6 GTEx Esophagus Mucosa C7orf73 0.42 0.31 lasso 6 0.38 1.3e-26 4.3 -5.4 5.6e-08 0.65 0.56 0.41 FALSE
7 GTEx Heart Atrial Appendage C7orf73 0.14 0.12 enet 10 0.09 7.4e-05 4.0 -5.1 3.0e-07 0.58 0.10 0.85 FALSE
8 GTEx Nerve Tibial C7orf73 0.19 0.10 lasso 9 0.18 9.5e-13 4.1 -5.8 7.8e-09 0.78 0.02 0.98 TRUE
9 GTEx Skin Not Sun Exposed Suprapubic C7orf73 0.38 0.33 lasso 5 0.37 2.3e-21 4.1 -5.2 2.4e-07 0.61 0.60 0.36 FALSE
10 GTEx Skin Sun Exposed Lower leg NUP205 0.07 0.03 lasso 4 0.04 6.2e-04 -4.8 5.1 2.7e-07 -0.82 0.02 0.88 FALSE
11 GTEx Skin Sun Exposed Lower leg C7orf73 0.29 0.28 enet 21 0.32 3.2e-27 4.1 -5.1 2.9e-07 0.58 0.65 0.31 FALSE
12 NTR Blood SLC13A4 0.02 0.01 bslmm 490 0.01 1.6e-03 4.3 5.5 5.1e-08 -0.42 0.13 0.32 FALSE