Best TWAS P=2.39e-08 · Best GWAS P=1.05e-07 conditioned to 0.0171
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | C8orf46 | 0.19 | 0.06 | enet | 11 | 0.03 | 1.6e-02 | -4.0 | 5.2 | 2.3e-07 | -0.60 | 0.09 | 0.57 | FALSE |
| 2 | GTEx | Esophagus Muscularis | C8orf46 | 0.39 | 0.22 | enet | 30 | 0.18 | 8.5e-11 | 4.2 | 5.6 | 2.4e-08 | -0.62 | 0.41 | 0.52 | TRUE |