Best TWAS P=2.12e-08 · Best GWAS P=1.25e-09 conditioned to 0.00109
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | VWA2 | 0.04 | 0.02 | blup | 67 | 0.03 | 1.7e-06 | 5.9 | -5.5 | 4.1e-08 | -0.82 | 0.01 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | C10orf118 | 0.03 | 0.01 | blup | 42 | 0.02 | 1.9e-03 | -3.5 | 5.6 | 2.1e-08 | 0.63 | 0.02 | 0.35 | TRUE |