Hub : Genes

C10orf118

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Stomach 0.1560 0.0570 0.0058 0.012 NA -0.005 NA 0.001 0.085 NA 0.7400 NA 0.280
2 TCGA Lung Adenocarcinoma 0.0298 0.0179 0.0053 0.011 0.02 0.014 NA 0.008 0.017 0.0019 0.0071 NA 0.038

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.7 1.1 1.9 0.4 -1.4
Bipolar Disorder or Schizophrenia 0.5 1.2 2.4 -0.2 -1.5
Depressed Affect (Nagel 2018) 0.7 1.6 2.7 -1.6 0.7
Depression (Nagel 2018) 1.3 2.0 2.9 -1.1 -1.7
Intelligence (Savage-Jansen 2018) 0.7 2.0 3.9 2.0 0.3
Neuroticism (Nagel 2018) 0.2 0.4 0.5 -0.5 0.7
Schizophrenia (2018) 0.3 0.5 0.7 -0.6 -0.9
Schizophrenia vs Biploar Disorder 0.4 0.6 1.1 -1.1 0.0
Worry (Nagel 2018) 0.0 0.0 0.1 -0.2 0.2
Alzheimer’s Disease (in mother) 0.0 0.1 0.1 -0.3 0.1
Alzheimer’s Disease (in father) 1.1 1.2 2.2 0.4 -1.5
Alzheimer’s Disease (including proxy) 0.0 0.0 0.0 0.1 -0.0
Crohns Disease (2017) 0.9 2.0 3.7 0.5 -1.9
Irritable Bowel Disease (IBD) 0.2 0.5 0.9 -0.4 -0.9
Ulcerative Colitis (UC) 0.5 0.9 1.7 -1.3 0.1
Major Depression (MDD) 0.6 0.8 1.5 -1.2 -0.3
Reaction Time 0.9 1.8 2.3 1.1 -1.5
Verbal and Numeric Reasoning (VNR) 0.3 0.8 1.5 1.2 -0.3
Breast Cancer 1.6 3.9 4.1 -1.9 2.0
Ovarian Cancer 0.8 1.1 2.1 -1.4 -0.3
Prostate Cancer 1.7 2.3 3.0 1.7 -1.3
Age at First Birth 0.1 0.1 0.2 -0.4 0.3
Bipolar Disorder (2011) 1.4 1.4 1.8 1.3 1.0
Body Mass Index (BMI) (2010) 0.9 1.2 2.1 -1.4 0.6
Coronary Artery Disease (CAD) 0.6 0.8 1.4 1.2 0.4
Crohns Disease (2012) 1.9 3.0 4.0 1.4 -2.0
Mean Putamen Volume 1.1 1.3 1.3 1.1 -1.1
Fasting Glucose 0.8 0.9 1.6 0.5 -1.2
HbA1C 0.2 0.2 0.4 0.2 -0.6
HDL Cholesterol 1.5 2.4 3.0 1.7 1.4
LDL Cholesterol 0.1 0.1 0.2 -0.4 0.1
Lupus 0.8 1.2 2.0 0.7 1.4
Neuroticism (2016) 0.3 0.4 0.6 -0.8 -0.4
Primary Biliary Cirrhosis 0.9 1.3 1.7 1.3 1.0
Rheumatoid Arthritis 1.1 1.5 2.2 -1.5 -0.9
Schizophrenia (2014) 0.6 1.3 1.9 -0.9 -1.4
Triglycerides 0.6 0.9 1.4 -0.7 1.2
Type 2 Diabetes (T2D) (2012) 0.4 0.4 0.9 0.2 -0.9
Ulcerative Colitis 0.8 1.1 2.3 -1.5 0.0
Blood Eosinophil Count 1.0 7.6 14.6 -0.8 3.8
Blood Platelet Count 0.0 0.2 0.3 -0.5 0.4
Blood Red Count 0.3 2.5 3.7 1.1 1.9
Blood White Count 2.0 14.9 29.6 -0.4 5.4
Heel T-Score 0.0 0.0 0.0 -0.2 -0.0
BMI 1.1 6.6 12.2 -0.9 3.5
Height 0.3 5.3 9.9 -0.9 3.1
Waist Hip Ratio (WHR) 0.1 0.7 0.8 0.7 0.9
Systolic Blood Pressure 4.8 23.8 47.3 0.6 6.9
Smoking Status 0.6 1.5 2.4 -0.8 1.5
Allergy or Eczema 0.4 1.0 1.9 -0.2 -1.4
Cardiovascular Disease 6.9 22.8 45.6 -0.1 6.8
Hypothyroidism (self reported) 0.2 0.5 0.9 -0.9 0.2
Respiratory disease 0.2 0.3 0.6 -0.2 -0.8
Type 2 Diabetes (T2D) (2018) 0.7 1.4 2.7 -1.6 -0.1
Lung FEV1/FVC ratio 0.1 0.4 0.8 -0.2 0.9
Lung FVC 0.3 1.4 1.8 -1.4 -0.9
Neuroticism 0.1 0.2 0.3 -0.5 0.2
Chronotype (morning person) 1.0 2.2 3.9 0.7 -2.0
Hair Pigment 0.1 2.7 5.4 0.2 -2.3
Tanning 0.0 0.2 0.4 -0.2 0.7
Hand grip strength (left) 0.1 0.3 0.7 0.1 0.8
Number of treatments/medications taken 0.7 1.2 1.7 1.3 0.8
Average weekly spirits intake 1.8 2.2 3.2 1.8 1.1
Sensitivity / hurt feelings 0.7 1.2 1.7 -0.9 1.3
Frequency of depressed mood in last 2 weeks 1.2 1.7 2.4 -1.6 -1.0
Hearing difficulty/problems: Yes 0.0 0.0 0.0 -0.2 0.2
Relative age of first facial hair 0.5 1.0 1.0 -1.0 1.0
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 0.4 -0.4 0.6
Ever used hormone-replacement therapy (HRT) 0.6 0.8 1.5 0.2 -1.2
Ever had hysterectomy (womb removed) 0.1 0.1 0.1 0.3 -0.3
Systolic blood pressure, automated reading 2.9 8.4 15.4 1.2 3.9
Eye problems/disorders: Diabetes related eye disease 0.7 0.8 1.5 -1.2 -0.3
Angina 1.7 2.3 2.4 -1.6 1.5
Medication for hormone replacement therapy 1.9 2.1 3.9 -0.6 -2.0
Vitamin and mineral supplements 0.2 0.3 0.6 0.8 0.0
Supplements: Zinc 0.5 0.5 0.8 0.5 -0.9
Medication: Co-codamol 2.6 3.1 5.8 -0.6 -2.4
Medication: Metformin 0.5 0.7 1.4 -1.2 0.0
Diabetes (father) 0.4 0.5 0.7 -0.8 -0.6
Diabetes (mother) 0.1 0.1 0.2 -0.4 -0.3
Severe depression (siblings) 0.9 1.1 2.1 1.5 -0.0
Pack years adult smoking proportion 2.9 4.4 8.3 -0.6 2.9
Impedance of leg (right) 1.7 8.1 10.2 2.4 -3.2
Leg fat-free mass (left) 3.5 18.8 30.7 -2.6 5.5
Trunk fat percentage 0.7 2.8 5.3 -0.6 2.3
Hand grip strength (right) 0.5 1.4 2.4 -0.7 1.6
Townsend deprivation index at recruitment 0.2 0.3 0.3 0.6 0.5
Current tobacco smoking 0.5 0.8 1.0 -0.8 1.0
Average weekly fortified wine intake 0.9 1.1 2.0 1.4 0.4
Maternal smoking around birth 0.3 0.4 0.4 0.6 0.6
Fed-up feelings 1.7 3.1 6.2 -2.5 0.1
Frequency of unenthusiasm / disinterest in last 2 weeks 1.8 2.4 3.4 -1.2 -1.8
Relative age voice broke 1.8 2.8 3.2 -1.8 1.6
Taking other prescription medications 0.1 0.1 0.2 -0.2 0.4
Age when periods started (menarche) 0.1 0.3 0.4 0.6 0.4
Bilateral oophorectomy (both ovaries removed) 0.8 0.9 1.0 1.0 -0.9
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 0.3 -0.5 0.5
Tinnitus: Yes, but not now, but have in the past 0.7 0.8 1.0 -0.7 1.0
Qualifications: CSEs or equivalent 0.3 0.4 0.9 -0.9 0.0
Serious illness, injury or assault to yourself 0.3 0.4 0.8 0.9 0.2
High blood pressure 5.8 16.0 32.0 0.2 5.7
Hayfever, allergic rhinitis or eczema 0.3 0.7 0.9 -0.7 -0.9
Multivitamins +/- minerals 0.4 0.6 0.7 -0.7 0.8
Stomach or abdominal pain in last month 0.1 0.1 0.2 0.2 0.5
Supplements: Glucosamine 0.8 1.0 2.0 -0.1 -1.4
Diverticular disease/diverticulitis (self-reported) 3.5 4.2 8.4 0.1 2.9
Medication: Atenolol 1.5 1.9 2.8 -1.7 1.0
Medication: Levothyroxine sodium 0.3 0.6 0.9 0.5 -0.9
Sitting height 1.6 11.3 21.3 -1.2 4.6
Chronic bronchitis/emphysema (father) 1.3 1.5 3.0 1.7 0.2
High blood pressure (mother) 4.4 6.2 12.3 0.3 3.5
Body mass index (BMI) 1.2 5.1 8.5 -1.4 2.9
Impedance of leg (left) 1.6 7.9 10.7 2.3 -3.3
Leg predicted mass (left) 3.5 18.5 29.8 -2.7 5.5
Trunk fat mass 1.7 7.2 13.0 -1.2 3.6
Waist circumference 2.0 7.5 12.9 -1.4 3.6
Number of incorrect matches in round 0.4 0.7 1.3 1.1 -0.2
Past tobacco smoking 0.2 0.4 0.7 0.4 -0.8
Alcohol usually taken with meals 2.1 3.4 6.5 0.5 -2.5
Nervous feelings 0.0 0.1 0.2 -0.1 -0.4
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 0.6 -0.6 -0.8
Hearing difficulty/problems with background noise 0.1 0.2 0.4 -0.1 0.6
Hair/balding pattern: Pattern 2 3.9 5.0 9.8 3.1 0.5
Had menopause 1.0 1.2 2.1 0.6 -1.4
Had other major operations 2.0 2.4 4.6 2.2 0.5
Forced vital capacity (FVC) 0.6 2.3 3.4 -1.1 1.9
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 0.5 -0.7 0.5
Ever unenthusiastic/disinterested for a whole week 2.3 2.8 4.5 -2.1 -1.0
Qualifications: None of the above 0.0 0.1 0.1 0.2 0.2
Financial difficulties in last 2 years 0.2 0.3 0.5 -0.7 0.3
Mouth/teeth dental problems 0.2 0.4 0.7 -0.8 0.2
Heart attack 0.1 0.2 0.3 0.5 0.2
Allergy 0.3 0.7 0.8 0.7 0.9
Pain all over the body in last month 0.7 0.8 1.4 0.4 1.2
Diabetes (self-reported) 0.6 0.9 1.3 -1.1 0.7
Hayfever/allergic rhinitis (self-reported) 0.1 0.1 0.2 0.1 0.4
Medication: Ramipril 4.2 5.4 9.7 -1.1 3.1
Medication: Simvastatin 0.9 1.4 2.8 0.1 1.7
Fluid intelligence score 0.0 0.1 0.1 0.1 0.3
Illnesses of siblings 2.6 3.7 4.1 -2.0 -1.8
Neuroticism score 1.2 2.5 4.1 -2.0 1.0
Weight 2.5 12.4 21.6 -1.8 4.6
Impedance of arm (right) 0.3 1.4 1.6 1.1 -1.3
Arm fat percentage (right) 1.2 4.8 8.4 -1.1 2.9
Trunk fat-free mass 2.6 15.1 26.2 -2.0 5.1
Hip circumference 2.5 10.7 16.9 -2.1 4.1
Time employed in main current job 0.3 0.3 0.6 -0.1 -0.8
Alcohol intake versus 10 years previously 0.2 0.3 0.5 -0.4 0.7
Father’s age at death 2.3 3.0 3.2 1.8 -1.7
Worrier / anxious feelings 0.3 0.5 1.1 -0.0 -1.0
Frequency of tiredness / lethargy in last 2 weeks 2.2 3.6 7.2 -2.7 0.2
Falls in the last year 0.4 0.5 0.6 -0.6 -0.8
Hair/balding pattern: Pattern 3 1.1 1.6 3.2 -1.8 0.1
Number of live births 0.2 0.3 0.6 0.8 0.2
Forced expiratory volume in 1-second (FEV1) 0.6 2.1 3.2 -1.1 1.8
Pulse rate 0.2 0.3 0.6 -0.8 0.3
Happiness 2.5 3.0 4.8 -1.2 -2.2
Noisy workplace 1.3 1.7 2.2 -1.1 -1.5
Qualifications: A levels/AS levels or equivalent 0.0 0.0 0.0 0.2 -0.2
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.5 0.9 1.0 0.1
Mouth/teeth dental problems: Dentures 0.3 0.5 0.7 0.5 -0.8
Asthma 0.2 0.4 0.7 0.4 -0.8
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.3 0.6 0.8 -0.2
Medication: Cholesterol lowering 0.1 0.1 0.2 0.2 -0.4
Depression (self-reported) 0.9 1.1 1.9 -0.6 -1.4
Medication: Lansoprazole 0.7 0.8 1.6 1.3 0.1
Prospective memory result 2.5 3.1 4.2 2.1 -1.4
Lung cancer (father) 1.0 1.1 1.8 0.7 1.4
Illnesses of mother 2.2 2.7 5.2 0.4 -2.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.2 1.4 -1.0 1.2
Pulse wave Arterial Stiffness index 0.0 0.0 0.1 -0.1 0.3
Impedance of arm (left) 0.7 3.4 5.0 1.3 -2.2
Arm fat mass (right) 1.9 7.8 13.7 -1.4 3.7
Trunk predicted mass 2.6 14.9 25.9 -2.0 5.1
Standing height 1.1 10.5 19.4 -1.3 4.4
Length of working week for main job 0.2 0.3 0.3 -0.4 0.6
Exposure to tobacco smoke at home 0.0 0.0 0.0 -0.1 -0.2
Breastfed as a baby 0.9 1.1 2.2 -0.2 -1.5
Tense / ‘highly strung’ 0.7 1.2 1.9 -1.4 0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.5 3.0 -1.7 0.3
Hair/balding pattern: Pattern 4 0.8 1.9 3.5 -1.9 0.5
Birth weight of first child 0.6 1.0 1.4 -0.8 1.2
Peak expiratory flow (PEF) 0.5 1.2 2.4 -0.3 1.6
Pulse wave reflection index 0.0 0.0 0.0 -0.2 -0.0
Ever highly irritable/argumentative for 2 days 0.3 0.4 0.6 -0.8 0.5
Loud music exposure frequency 0.3 0.3 0.6 -0.8 0.2
Qualifications: O levels/GCSEs or equivalent 0.4 0.7 1.4 1.2 0.0
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 1.1 1.0 0.4
Blood clot in the leg (DVT) 0.3 0.3 0.7 -0.0 0.8
Medication: Paracetamol 0.4 0.7 1.2 1.1 0.5
Headache pain in last month 0.7 1.2 1.6 1.3 1.0
Medication for cholesterol, blood pressure or diabetes 2.2 3.6 7.2 -0.2 -2.7
Glaucoma (self-reported) 0.1 0.1 0.2 0.1 0.4
Gout (self-reported) 0.7 1.0 2.0 -1.4 -0.1
Hypothyroidism/myxoedema (self-reported) 0.1 0.1 0.1 0.4 0.3
Medication: Amlodipine 5.1 7.1 14.2 0.1 3.8
Medication: Ventolin 100micrograms inhaler 0.2 0.3 0.3 -0.5 -0.6
Birth weight 3.5 7.6 14.3 0.9 3.8
Chronic bronchitis/emphysema (mother) 0.3 0.4 0.7 -0.0 -0.8
High blood pressure (siblings) 3.4 5.0 8.0 1.4 2.8
Forced vital capacity (FVC), Best measure 0.4 1.6 2.2 -1.0 1.5
Body fat percentage 0.7 2.7 5.0 -0.6 2.2
Leg fat percentage (right) 0.2 0.9 1.7 0.3 1.3
Arm fat-free mass (right) 2.5 12.6 20.8 -2.1 4.6
Exposure to tobacco smoke outside home 0.8 1.0 2.0 -0.1 1.4
Comparative body size at age 10 0.4 1.1 2.1 -1.5 -0.1
Number of full brothers 0.4 0.5 0.6 0.6 0.8
Worry too long after embarrassment 0.4 0.6 0.6 0.8 0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.1 0.1 0.2 -0.5 -0.3
Wheeze or whistling in the chest in last year 0.6 1.0 1.7 -1.3 0.6
Number of children fathered 1.7 1.9 3.5 -1.9 -0.6
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 1.8 1.3 0.0
Age at first live birth 0.1 0.2 0.4 0.1 0.6
Pulse wave peak to peak time 0.1 0.1 0.1 -0.1 0.4
Health satisfaction 0.2 0.2 0.2 0.5 -0.5
Shortness of breath walking on level ground 0.6 0.7 1.2 -0.5 -1.1
Qualifications: College or University degree 0.5 1.6 2.0 1.0 -1.4
Eye problems/disorders: None of the above 0.3 0.4 0.4 0.7 0.6
Mouth/teeth dental problems: Loose teeth 0.3 0.4 0.5 0.7 0.5
Emphysema/chronic bronchitis 2.4 2.7 5.4 -2.3 0.1
Medication for pain relief, constipation, heartburn 0.8 1.4 2.4 -0.7 -1.5
Neck or shoulder pain in last month 0.1 0.2 0.4 -0.1 0.6
Medication: Blood pressure 4.1 7.3 14.5 0.3 3.8
Angina (self-reported) 1.5 2.0 2.2 -1.3 1.5
Migraine (self-reported) 0.3 0.4 0.7 0.9 -0.1
Medication: Ibuprofen 0.5 0.5 0.8 0.9 -0.5
Medication: Allopurinol 0.5 0.7 1.4 -1.2 0.1
Medication: Omeprazole 0.6 0.7 1.0 -0.6 1.0
Medication: Seretide 50 evohaler 0.3 0.4 0.6 -0.8 0.4
Mean time to correctly identify matches 1.4 2.7 3.5 1.9 -1.4
Heart disease (mother) 0.4 0.5 0.7 -0.5 0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.0 2.3 3.9 0.9 -2.0
Whole body fat mass 1.9 7.9 13.9 -1.4 3.7
Leg fat mass (right) 1.6 6.0 11.1 -1.0 3.3
Arm predicted mass (right) 2.6 13.2 21.9 -2.1 4.7
Pulse rate, automated reading 0.3 1.0 2.0 -1.4 0.2
Alcohol intake frequency. 0.1 0.1 0.3 -0.1 0.5
Comparative height size at age 10 1.0 5.4 10.7 0.1 3.3
Number of full sisters 0.1 0.2 0.3 0.5 0.3
Suffer from ‘nerves’ 0.2 0.4 0.7 -0.8 0.0
Overall health rating 0.6 1.2 1.8 -1.4 0.8
Chest pain or discomfort 0.1 0.2 0.4 0.1 0.6
Had major operations 0.1 0.1 0.2 0.5 0.2
Age at last live birth 0.3 0.5 0.9 -1.0 0.2
Family relationship satisfaction 0.4 0.5 0.9 -0.9 0.3
Leg pain on walking 0.8 1.0 1.9 1.4 0.3
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 0.4 -0.2 0.7
Commuting to job workplace: Car/motor vehicle 0.1 0.1 0.1 -0.3 -0.2
Illness, injury, bereavement, stress in last 2 years 0.9 1.1 1.6 -1.3 -0.8
Medication: Aspirin 0.1 0.2 0.2 0.3 0.5
Supplements: Vitamin C 0.2 0.2 0.4 -0.6 -0.4
Knee pain experienced in last month 1.3 2.0 3.8 2.0 -0.4
Hypertension (Self-reported) 5.8 16.0 31.5 0.7 5.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 0.6 -0.8 -0.4
Illnesses of father: Heart disease 0.3 0.4 0.8 -0.9 0.2
Illnesses of siblings: Diabetes 1.0 1.2 2.1 -0.5 1.5
Smoking status: Previous 0.1 0.1 0.1 -0.4 0.3
Forced expiratory volume in 1-second (FEV1), predicted 1.1 2.4 3.8 -0.9 2.0
Whole body fat-free mass 3.1 17.6 29.6 -2.4 5.4
Leg fat-free mass (right) 3.5 18.9 30.8 -2.6 5.5
Arm fat percentage (left) 1.0 4.0 7.1 -1.0 2.7
Average weekly red wine intake 0.7 1.0 2.0 1.4 0.2
Handedness (chirality/laterality): Left-handed 0.5 0.7 0.9 -1.0 -0.6
Mood swings 1.8 3.3 5.3 -2.3 1.1
Loneliness, isolation 1.3 1.9 3.5 -1.9 -0.4
Long-standing illness, disability or infirmity 1.0 1.5 3.0 0.2 1.7
Ever had bowel cancer screening 1.1 1.3 2.6 1.6 0.1
Diabetes diagnosed by doctor 0.5 0.9 1.7 -1.3 0.1
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.1 0.3 -0.3
Friendships satisfaction 1.4 1.7 3.3 -0.4 -1.8
Qualifications: nursing, teaching 0.3 0.5 0.8 0.5 -0.9
Commuting to job workplace: Walk 0.1 0.1 0.1 -0.2 -0.3
Eye problems/disorders: Cataract 0.3 0.3 0.7 -0.0 -0.8
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 0.3 0.2 0.5
Medication for cholesterol 0.6 0.9 1.7 0.2 -1.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 1.1 1.1 -0.3
Back pain experienced in last month 0.4 0.5 0.8 0.5 0.9
Mineral and other dietary supplements 1.5 2.0 4.0 0.2 2.0
Breast cancer (self-reported) 0.3 0.4 0.6 0.8 0.5
Asthma (self-reported) 0.1 0.2 0.4 -0.1 -0.6
Osteoporosis (self-reported) 1.1 1.3 2.5 0.4 -1.6
Osteoarthritis (self-reported) 0.8 1.0 1.5 -0.8 -1.2
Medication: Aspirin 0.3 0.4 0.7 0.1 0.8
Medication: Gliclazide 1.2 1.3 1.6 -1.0 -1.3
Illnesses of father: None of the above (group 1) 0.3 0.4 0.6 0.8 -0.4
Smoking status: Current 0.5 0.8 0.9 -0.8 1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.0 2.1 4.0 -0.4 -2.0
Whole body water mass 2.9 16.7 28.2 -2.3 5.3
Leg predicted mass (right) 3.6 19.5 31.4 -2.8 5.6
Arm fat mass (left) 1.8 7.5 13.0 -1.4 3.6
Number of self-reported non-cancer illnesses 0.9 1.5 3.0 0.2 1.7
Average weekly champagne plus white wine intake 1.0 1.3 2.5 0.5 -1.6
Miserableness 1.1 1.9 2.7 -1.1 1.6
Guilty feelings 0.4 0.6 0.6 -0.7 -0.8
Wears glasses or contact lenses 0.9 1.1 2.1 1.5 -0.1
Ever taken oral contraceptive pill 0.6 0.7 1.4 -1.2 -0.1
Hearing aid user 0.3 0.4 0.8 -0.0 0.9
Mother’s age at death 1.3 1.6 2.0 -1.1 -1.4
Financial situation satisfaction 1.0 1.3 2.5 -1.6 -0.2
Tinnitus: Yes, now most or all of the time 3.0 3.5 4.6 1.6 2.1
Commuting to job workplace: Public transport 0.0 0.1 0.1 0.2 -0.2
Eye problems/disorders: Glaucoma 0.2 0.2 0.4 -0.6 -0.2
Medication: Blood pressure 3.9 7.4 14.7 0.3 3.8
Pain type(s) experienced in last month: Hip pain 1.4 1.8 3.5 1.9 0.2
Supplements: Fish oil (including cod liver oil) 0.5 0.6 1.0 -0.6 -1.0
High cholesterol (Self-reported) 0.1 0.1 0.2 0.2 0.4
Medication: Bendroflumethiazide 2.8 4.2 4.4 2.0 2.1
Medication: Paracetamol 0.7 1.2 1.2 1.1 1.1
Medication: Lisinopril 3.2 4.2 4.3 2.0 2.1
Medication: Atorvastatin 0.6 0.7 1.2 0.5 -1.1
Illnesses of father: High blood pressure 1.2 1.5 2.5 -1.6 0.7
Alcohol drinker status: Never 0.0 0.0 0.0 -0.1 0.1
Ever smoked 0.1 0.1 0.2 -0.0 0.5
Basal metabolic rate 3.2 17.5 29.6 -2.3 5.4
Leg fat percentage (left) 0.2 0.8 1.6 0.0 1.3
Arm fat-free mass (left) 2.5 12.7 21.3 -2.0 4.6
Number of operations (self-reported) 1.0 1.4 2.7 1.6 -0.4
Average weekly beer plus cider intake 1.4 2.0 3.8 -1.9 -0.4
Irritability 1.1 1.9 3.4 -1.8 0.6
Risk taking 1.2 1.7 1.8 1.3 1.3
Ever had prostate specific antigen (PSA) test 0.3 0.3 0.6 -0.2 0.8
Fractured/broken bones in last 5 years 2.0 2.6 4.7 0.7 2.2
Age started oral contraceptive pill 2.8 3.5 4.8 1.5 -2.2
Diastolic blood pressure, automated reading 6.4 19.9 39.9 -0.1 6.3
Ever depressed for a whole week 1.0 1.2 1.5 -1.2 -0.9
Unable to work because of sickness or disability 0.3 0.3 0.6 0.3 0.8
Commuting to job workplace: Cycle 1.9 2.3 4.6 2.1 -0.3
Myopia 0.4 0.6 1.1 -0.1 1.1
Vascular/heart problems diagnosed by doctor 6.5 17.7 35.5 0.2 -6.0
Cholesterol lowering medication 0.4 0.6 1.1 -0.3 1.0
Medication: Omeprazole (e.g. Zanprol) 1.2 1.5 2.2 -0.8 1.5
Pain experienced in last month 0.3 0.6 1.1 -1.1 -0.1
Supplements: Calcium 0.5 0.6 1.1 1.0 -0.2
Basal cell carcinoma (self-reported) 1.5 1.8 3.6 -0.2 -1.9
Heart attack/myocardial infarction (self-reported) 0.2 0.3 0.4 0.6 0.4
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 0.9 -0.0 1.0
Heart disease (siblings) 1.3 1.6 3.1 1.8 0.1
Alcohol drinker status: Previous 0.3 0.3 0.5 0.7 -0.4
Pack years of smoking 1.6 2.4 4.6 -0.3 2.1
Impedance of whole body 1.2 6.2 8.3 2.0 -2.9
Leg fat mass (left) 1.6 6.3 11.1 -1.2 3.3
Arm predicted mass (left) 2.4 12.4 21.3 -1.9 4.6